anti-Mannosidase, Alpha, Class 2B, Member 1 Antibodies

MAN2B1 encodes an enzyme that hydrolyzes terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.

Data Quality
  • 5
Type
  • 11
    Primary
Antigen
  • 11
Reactivity
  • 9
  • 2
Application
  • 11
  • 2
  • 1
  • 1
  • 1
Host
  • 7
  • 4
Clonality
  • 10
  • 1
Binding Specificity
  • 6
  • 1
Isotype
  • 8
Format
  • 9
11 Products
ReactivityHuman
Application ICC, IHC, WB
Order details Cat. No. ABIN1869071
$245.00
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN948102
$425.71
100 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN6143456
$393.25
Plus shipping costs $45.00
Delivery in 13 to 14 Business Days
ReactivityMouse (Murine)
Application WB
Order details Cat. No. ABIN4904287
$368.95
100 μL
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityMouse (Murine)
Application WB
Order details Cat. No. ABIN3068887
$422.09
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN517725
$440.00
50 μg
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application ICC, IHC (fro), IHC (p), ELISA, WB
Order details Cat. No. ABIN1865072
$370.00
200 μL
Plus shipping costs $45.00
Delivery in 13 to 16 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN2306169
$625.43
50 μg
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN2306170
$666.29
100 μg
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN2586838
$837.83
50 μg
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN2586839
$903.83
100 μg
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
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Mannosidase, Alpha, Class 2B, Member 1 (MAN2B1) Antigen Profile

Protein Summary

This gene encodes an enzyme that hydrolyzes terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. Its activity is necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover and it is member of family 38 of glycosyl hydrolases. The full length protein is processed in two steps. First, a 49 aa leader sequence is cleaved off and the remainder of the protein is processed into 3 peptides of 70 kDa, 42 kDa (D) and 13/15 kDa (E). Next, the 70 kDa peptide is further processed into three peptides (A, B and C). The A, B and C peptides are disulfide-linked. Defects in this gene have been associated with lysosomal alpha-mannosidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with MAN2B1

  • mannosidase alpha class 2B member 1 (MAN2B1) antibody
  • mannosidase, alpha, class 2B, member 1 (man2b1) antibody
  • mannosidase 2, alpha B1 (Man2b1) antibody
  • mannosidase alpha class 2B member 1 (Man2b1) antibody
  • mannosidase, alpha, class 2B, member 1 (Man2b1) antibody
  • AW107687 antibody
  • Laman antibody
  • MANB antibody

Protein level used designations for MAN2B1

mannosidase, alpha, class 2B, member 1 , lysosomal alpha-mannosidase (109.3 kD) (XF355) , lysosomal alpha-mannosidase , lysosomal alpha-mannosidase-like , lysosomal acid alpha-mannosidase , mannosidase alpha class 2B member 1 , mannosidase alpha-B , mannosidase 2, alpha B1 , mannosidase, alpha B, lysosomal , laman

GENE ID SPECIES
484932 Canis lupus familiaris
779924 Xenopus (Silurana) tropicalis
100010377 Monodelphis domestica
100174476 Pongo abelii
100395073 Callithrix jacchus
100598622 Nomascus leucogenys
17159 Mus musculus
100718205 Cavia porcellus
361378 Rattus norvegicus
4125 Homo sapiens
282272 Bos taurus
493697 Felis catus