anti-Melanoma Antigen Family A, 2 (MAGEA2) Antibodies

MAGEA2 is a member of the MAGEA gene family. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MAGEA2 17138  
MAGEA2 4101 P43356
MAGEA2    
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Top anti-MAGEA2 Antibodies at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-MAGEA2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate WB Suggested Anti-MAGEA2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-MAGEA2 N-term Antibody (ABIN390106) is used in Western blot to detect MAGEA2 in HL60 lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of MAGE2 using COLO205 whole cell lysates 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Mouse Un-conjugated ELISA, WB MAGEA2 monoclonal antibody (M01), clone 1H4 Western Blot analysis of MAGEA2 expression in Jurkat . Western Blot analysis of MAGEA2 expression in transfected 293T cell line by MAGEA2 monoclonal antibody (M01), clone 1H4.Lane 1: MAGEA2 transfected lysate(35 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 11 to 12 Days
$440.00
Details
Cow Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 16 Days
$293.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA 50 μg Log in to see 12 to 14 Days
$673.48
Details
Human Rabbit Un-conjugated IHC, ELISA 0.05 mg Log in to see 2 to 3 Days
$618.75
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 11 to 14 Days
$537.17
Details

More Antibodies against MAGEA2 Interaction Partners

Human Melanoma Antigen Family A, 2 (MAGEA2) interaction partners

  1. Data indicate that melanoma-associated antigen A2 (MAGEA2)is significantly overexpressed in triple-negative breast cancer (TNBC) tissues and is important for progression of TNBC and may serve as a novel molecular therapeutic target.

  2. suppression of MAGEA2 in lung cancer cells significantly reduced the growth/survival of cancer cells. High-MAGEA2 was identified as an independent prognostic factor in lung adenocarcinoma. Specific inhibition of MAGEA2 may be a promising therapeutic strategy for patients with lung cancer.

  3. Immunohistochemistry using D2-40 monoclonal antibody (MAGE2) and anti-MITF1 increased detection of lymphovascular invasion in primary cutaneous melanoma.

  4. We find that MAGE-A2 interacts with MDM2 via the N-terminal p53-binding pocket and the RING finger domain of MDM2 that is required for homo/hetero-dimerization and for E2 ligase interaction.

  5. Consistent with increased cell death, the induced loss of MAGEA2 expression correlated with increased caspase 3/7 activity, BCL2/BAX ratio and TUNEL signal.

  6. MAGEA2 has a critical role in the development of tamoxifen-resistant breast cancer

  7. MageA2 interferes with p53 acetylation at PML-nuclear bodies (NBs) and with PMLIV-dependent activation of p53.

  8. Report MAGEA1-A6 expression in sputum suggests presence of lung cancer cells or precancerous cells.

  9. These data suggest that MAGEA2 is differentially expressed in HNSCC and functions, in part, through the p53 pathway by increasing cellular proliferation and abrogating cell cycle arrest.

  10. MAGE-A2 targets p53 transactivation function through histone deacetylase recruitment

  11. These data show, for the first time, the involvement of methyl-CpG binding domain proteins in the regulation of the MAGE-A genes.

  12. Multiple simultaneous detection of MAGE-A [subtypes] more specific and sensitive than detection of single MAGE-A antigen for the diagnostic and prognostic evaluation of oral squamous cell carcinoma

MAGEA2 Antigen Profile

Protein Summary

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.

Gene names and symbols associated with MAGEA2

  • melanoma antigen, family A, 2 (Magea2) antibody
  • melanoma-associated antigen 2 (LOC706218) antibody
  • MAGE family member A2 (MAGEA2) antibody
  • CT1.2 antibody
  • Mage-a2 antibody
  • MAGE2 antibody
  • MAGEA2 antibody
  • MAGEA2A antibody

Protein level used designations for MAGEA2

melanoma antigen family A, 2 , MAGE-2 antigen , cancer/testis antigen 1.2 , cancer/testis antigen family 1, member 2 , melanoma antigen 2 , melanoma-associated antigen 2

GENE ID SPECIES
17138 Mus musculus
706218 Macaca mulatta
4101 Homo sapiens
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