anti-Melanoma Antigen Family A, 2 (MAGEA2) Antibodies

MAGEA2 is a member of the MAGEA gene family.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse MAGEA2 MAGEA2 17138  
Anti-Human MAGEA2 MAGEA2 4101 P43356
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Top anti-MAGEA2 Antibodies at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB <b>WB Suggested Anti-MAGEA2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-MAGEA2 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-MAGEA2 N-term Antibody (ABIN390106) is used in Western blot to detect MAGEA2 in HL60 lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p) Human Testis (formalin-fixed, paraffin-embedded) stained with MAGEA2 antibody ABIN214688 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$484.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, WB MAGEA2 monoclonal antibody (M01), clone 1H4 Western Blot analysis of MAGEA2 expression in Jurkat . Western Blot analysis of MAGEA2 expression in transfected 293T cell line by MAGEA2 monoclonal antibody (M01), clone 1H4.<br><br>Lane 1: MAGEA2 transfected lysate(35 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μg Log in to see 11 to 12 Days
$440.00
Details
Cow Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), ELISA 50 μg Log in to see 12 to 14 Days
$685.40
Details
Human Rabbit Un-conjugated IHC, ELISA 0.05 mg Log in to see 2 to 3 Days
$550.00
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 7 to 9 Days
$537.17
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 7 to 9 Days
$1,013.83
Details

More Antibodies against MAGEA2 Interaction Partners

Human Melanoma Antigen Family A, 2 (MAGEA2) interaction partners

  1. Data indicate that melanoma-associated antigen (show ZNF654 Antibodies) A2 (MAGEA2)is significantly overexpressed in triple-negative breast cancer (TNBC) tissues and is important for progression of TNBC and may serve as a novel molecular therapeutic target.

  2. suppression of MAGEA2 in lung cancer cells significantly reduced the growth/survival of cancer cells. High-MAGEA2 was identified as an independent prognostic factor in lung adenocarcinoma. Specific inhibition of MAGEA2 may be a promising therapeutic strategy for patients with lung cancer.

  3. Immunohistochemistry using D2-40 monoclonal antibody (MAGE2) and anti-MITF1 increased detection of lymphovascular invasion in primary cutaneous melanoma.

  4. We find that MAGE-A2 interacts with MDM2 (show MDM2 Antibodies) via the N-terminal p53 (show TP53 Antibodies)-binding pocket and the RING finger (show PCGF1 Antibodies) domain of MDM2 (show MDM2 Antibodies) that is required for homo/hetero-dimerization and for E2 ligase interaction.

  5. Consistent with increased cell death, the induced loss of MAGEA2 expression correlated with increased caspase 3 (show CASP3 Antibodies)/7 activity, BCL2 (show BCL2 Antibodies)/BAX (show BAX Antibodies) ratio and TUNEL signal.

  6. MAGEA2 has a critical role in the development of tamoxifen-resistant breast cancer

  7. MageA2 interferes with p53 (show TP53 Antibodies) acetylation at PML (show PML Antibodies)-nuclear bodies (NBs (show NBN Antibodies)) and with PMLIV-dependent activation of p53 (show TP53 Antibodies).

  8. Report MAGEA1 (show MAGEA1 Antibodies)-A6 expression in sputum suggests presence of lung cancer cells or precancerous cells.

  9. These data suggest that MAGEA2 is differentially expressed in HNSCC and functions, in part, through the p53 (show TP53 Antibodies) pathway by increasing cellular proliferation and abrogating cell cycle arrest.

  10. MAGE-A2 targets p53 (show TP53 Antibodies) transactivation function through histone deacetylase (show HDAC1 Antibodies) recruitment

MAGEA2 Antigen Profile

Protein Summary

This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.

Gene names and symbols associated with MAGEA2

  • melanoma antigen, family A, 2 (Magea2) antibody
  • melanoma-associated antigen 2 (LOC706218) antibody
  • MAGE family member A2 (MAGEA2) antibody
  • CT1.2 antibody
  • Mage-a2 antibody
  • MAGE2 antibody
  • MAGEA2 antibody
  • MAGEA2A antibody

Protein level used designations for MAGEA2

melanoma antigen family A, 2 , MAGE-2 antigen , cancer/testis antigen 1.2 , cancer/testis antigen family 1, member 2 , melanoma antigen 2 , melanoma-associated antigen 2

GENE ID SPECIES
17138 Mus musculus
706218 Macaca mulatta
4101 Homo sapiens
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