MAGEA2 antibody (N-Term)

Catalog No. ABIN390106

Product Details anti-MAGEA2 Antibody

Target: MAGEA2 (Melanoma Antigen Family A, 2 (MAGEA2))

Binding Specificity: AA 81-108, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MAGEA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the N-terminal region of human MAGEA2.

Clone: RB2194

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for MAGEA2

Target: MAGEA2 (Melanoma Antigen Family A, 2 (MAGEA2))

Alternative Name: MAGEA2 (MAGEA2 Products)

Synonyms: Mage-a2 antibody, MAGEA2 antibody, CT1.2 antibody, MAGE2 antibody, MAGEA2A antibody, melanoma antigen, family A, 2 antibody, melanoma-associated antigen 2 antibody, MAGE family member A2 antibody, Magea2 antibody, LOC706218 antibody, MAGEA2 antibody

Background: MAGEA2 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80 % sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci.

Gene ID: 4101

NCBI Accession: NP_005352, NP_705692, NP_786884, NP_786885

UniProt: P43356