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may be involved in cartilage development [RGD, Feb 2006].. Additionally we are shipping MIA Antibodies (45) and MIA Kits (13) and many more products for this protein.
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The frequency of MIA gene family expression was higher among squamous cell carcinomas than among other tumor types subjected to screening. MIA gene family staining was observed frequently in esophageal and lung cancers associated with nodal and/or distant metastasis. In cervical cancers, MIA and TANGO (show ARNT Proteins) immunostaining also correlated with tumor progression and metastasis.
Our results suggest that MIA-STOX2 signaling may be a useful diagnostic and therapeutic target in oral squamous cell carcinoma
MIA had a slightly superior sensitivity to detect progressive disease compared to S100 and seems to be more useful in monitoring of patients with metastatic melanoma receiving immunotherapy
real-time RT-PCR assays showed that expressions of MIA and MIA-RAB4B (show RAB4B Proteins) located 35 kb upstream of the deletion, were up-regulated in the polyps compared to the matched mucosa of the proband. MIA-RAB4B (show RAB4B Proteins), the read-through long non-coding RNA (lncRNA), RAB4B (show RAB4B Proteins), PIM2 (show PIM2 Proteins) and TAOK1 (show TAOK1 Proteins) share common binding site of a microRNA, miR (show MLXIP Proteins)-24, in their 3'UTRs
The effects of MIA/CD-RAP on transcriptional regulation in chondrocytes, through the regulation of p54(nrb (show NONO Proteins)) via YBX1 (show YBX1 Proteins) contributes to the understanding of chondrogenesis.
data provide evidence for a critical role of SOX10 (show SOX10 Proteins) in melanoma cell invasion through the regulation of MIA and highlight its role as a therapeutic target in melanoma
Focus on the quantitative analysis of the MIA protein as a prognostic tool because it has proven to be a useful serum marker for documenting disease progression of malignant melanoma. Review.
Functional promoter analysis identified the transcription factor YBX1 (show YBX1 Proteins) as the mediator of MIA activation of p54(nrb (show NONO Proteins)) transcription.
MIA protein is present in non-segmental vitiligo (show MITF Proteins) skin and may cause the detachment of melanocytes; its target is integrin alpha5beta1, which determines the breaking and/or weakening of connections among melanocytes and basal membrane
Results show that S-100B, MIA and LDH levels were significantly higher in patients with advanced melanoma than in disease-free patients or healthy controls.
Attenuated LM expressing MIA.
as observed in other knockout models of molecules important for cartilage development and differentiation, viability and functional integrity is reached by remarkable molecular redundancy in MIA/CD-RAP knockout mice.
The cartilage protein melanoma inhibitory activity contributes to inflammatory arthritis.
Expression analysis of cartilage tissue derived from MIA-/- mice revealed strong downregulation of nuclear RNA-binding protein 54-kDa.
MIA/CD-RAP stabilizes cartilage differentiation and inhibits differentiation into bone potentially by regulating signaling processes during differentiation.
transcriptional mechanism by which CD-RAP expression is suppressed by IL-1 beta (show IL1B Proteins)
Cdrap/Mia is located between two housekeeping genes
DNA promoter segment from -2,251 bp to -2,068 bp of the CD-RAP gene contains elements critical for gene expression. It demonstrates activation or repression of gene expression in vitro and in vivo based on cell type and content of transcription factors.
A potential tumor suppressor role of Mia/Cd-rap in pituitary cells.
may be involved in cartilage development
melanoma-derived growth regulatory protein
, melanoma inhibitory activity-like
, Melanoma-derived growth regulatory protein
, melanoma inhibitory activity 1
, melanoma inhibitory activity protein
, cartilage derived retinoic acid sensitive protein
, cartilage-derived retinoic acid-sensitive protein
, melanoma inhibitory activity/condrocyte-derived retinoic acid sensitive protein homolog (MIA/CD-RAP)
, melanoma inhibitory activity-like protein