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Metallothioneins have a high content of cysteine residues that bind various heavy metals\; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.. Additionally we are shipping Metallothionein 1E Kits (18) and Metallothionein 1E Proteins (7) and many more products for this protein.
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Forced MT1E expression rescues both hypersensitivity of CDKAL1 mutant cells to glycolipotoxicity and pancreatic beta-cell dysfunction in vitro and in vivo.
MT1E can enhance the migration and invasion of human glioma cells by inducing MMP-9 inactivation via the upregulation of NF-kappaB p50.
Our results reveal that menopause influences the adipose tissue expression of many genes, especially of neurexin 3, metallothionein 1E, and keratyn 7, which are associated with the alteration of several key biological processes.
MT1E is a potential tumour suppressor gene, whose loss may promote resistance to apoptosis-inducing therapies.
Increases in MT gene expression and intracellular zinc levels may contribute directly to maintenance of an immune-activated monocyte by mediating an increased resistance to apoptosis during active HIV-1 viremia.
Eight MT genes were up-regulated after treatment of T-ALL cells with 0.15 and 1.5 microg/mL of metal ores. Heavy metal ion transporter activity.
analysis identified genes known to be associated with cell invasion such as versican, and novel ones, including metallothionein 1E (MT1E) and nicotinamide N-methyltransferase (NNMT)
High frequency of hypermethylation of MT-1E was found in endometrial carcinomas.
Metallothioneins have a high content of cysteine residues that bind various heavy metals\; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
, metallothionein 1E (functional)
, metallothionein D
, metallothionein 1E