anti-Mitochondrial Transcription Termination Factor (MTERF) Antibodies

MTERF encodes a mitochondrial transcription termination factor. Additionally we are shipping Mitochondrial Transcription Termination Factor Proteins (6) and Mitochondrial Transcription Termination Factor Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MTERF 85261 Q9EPI8
MTERF 7978 Q99551
MTERF    
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Top anti-Mitochondrial Transcription Termination Factor Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: MTERF1 Sample Tissue: Human Fetal Kidney Antibody Dilution: 1ug/ml 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of mTERF expression in HeLa (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MTERF Antibody. The picture on the right is treated with the synthesized peptide. Western blot analysis of extracts from Jurkat cells, using MTERF Antibody. The lane on the right is treated with the synthesized peptide. 100 μg 2 to 3 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB 100 μL 11 to 14 Days
$493.17
Details
Human Rabbit Un-conjugated ELISA, ICC, IF, IHC, WB ABIN6275640 staining Hela cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod ABIN6275640 at 1/100 staining Human lung cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ELISA, IHC, WB   100 μL 11 to 13 Days
$359.79
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg 2 to 3 Days
$324.50
Details
Mouse Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using MTERF1 antibody (ABIN6291170) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s. 50 μL 11 to 13 Days
$305.01
Details
Human Mouse Un-conjugated ELISA   100 μg 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$375.83
Details

More Antibodies against Mitochondrial Transcription Termination Factor Interaction Partners

Human Mitochondrial Transcription Termination Factor (MTERF) interaction partners

  1. MTERF1 has the ability to accommodate alternate active conformations.

  2. It has been demonstrated that MTERF1 arrests mitochondrial DNA (mtDNA) replication with distinct polarity whereby MTERF1 acts as a directional contra-helicase, blocking mtDNA unwinding by the mitochondrial helicase TWINKLE.

  3. Studies indicate that the structure of the mitochondrial transcription termination factor (MTERF1) provides insight into the mechanism of binding, recognition of the termination sequence and the conformational changes involved in mediating termination.

  4. Single nucleotide polymorphism in MTERF gene is associated with epithelial ovarian cancer.

  5. data suggested that hMTERF4 is an essential factor for cell proliferation, which is probably modulated by mitochondrial transcription to promote cell proliferation

  6. Data show that mTERF protein levels materially affect the amount of readthrough transcription on the antisense strand of mtDNA, whilst the effects on sense-strand transcripts are complex, and suggest the influence of compensatory mechanisms.

  7. Presented are the crystal structures of human mitochondrial regulator MTERF, a transcription termination factor also implicated in replication pausing, in complex with double-stranded DNA oligonucleotides containing the tRNA(Leu)(UUR) gene sequence.

  8. The structure indicates that upon sequence recognition MTERF1 unwinds the DNA molecule, promoting eversion of three nucleotides.

  9. mTERF mRNA levels were higher in elite athletes compared with moderately active subjects

  10. mTERF exists in mitochondria in two forms, an active monomer and an inactive large size complex

  11. monomeric human mTERF is fully active in its non-phosphorylated form and that the protein does not require additional cellular factors to terminate mitochondrial transcription in vitro

  12. analysis of DNA light-strand preferential recognition of human mitochondria transcription termination factor mTERF

  13. Results indicate a role for mTERF in mtDNA replication, in addition to its role in transcription.

Fruit Fly (Drosophila melanogaster) Mitochondrial Transcription Termination Factor (MTERF) interaction partners

  1. mTerf5 knockdown led to enhanced replication pausing at mTTF binding sites, a decrease in fragile replication intermediates containing single-stranded segments, and the disappearance of species containing segments of RNA/DNA hybrid

  2. The first ever-obtained evidence for an in vivo role of an animal mitochondrial transcription termination factor.

  3. DmTTF might play multiple roles in the mtDNA transcription process, for which different levels of the protein with respect to mtRNApol are required.

Mitochondrial Transcription Termination Factor (MTERF) Antigen Profile

Protein Summary

This gene encodes a mitochondrial transcription termination factor. This protein participates in attenuating transcription from the mitochondrial genome\; this attenuation allows higher levels of expression of 16S ribosomal RNA relative to the tRNA gene downstream. The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding. There is evidence that, for this protein, the zippers participate in intramolecular interactions that establish the three-dimensional structure required for DNA binding.

Gene names and symbols associated with MTERF

  • mitochondrial transcription termination factor 1 (MTERF1) antibody
  • mitochondrial transcription termination factor (MTERF) antibody
  • mitochondrial transcription termination factor 1 (Mterf1) antibody
  • mitochondrial transcription termination factor 1 (mterf1) antibody
  • mitochondrial transcription termination factor (mTTF) antibody
  • BG:DS01068.4 antibody
  • CG18124 antibody
  • Dmel\\CG18124 antibody
  • DmTTF antibody
  • DS01068.4 antibody
  • Mterf antibody

Protein level used designations for MTERF

mitochondrial transcription termination factor , Transcription termination factor, mitochondrial , mitochondrial transcription termination factor 1 , transcription termination factor, mitochondrial , CG18124-PA , mTTF-PA , transcription termination factor 1, mitochondrial

GENE ID SPECIES
703725 Macaca mulatta
472439 Pan troglodytes
100172789 Pongo abelii
85261 Rattus norvegicus
522191 Bos taurus
549783 Xenopus (Silurana) tropicalis
7978 Homo sapiens
34837 Drosophila melanogaster
100355865 Oryctolagus cuniculus
100716389 Cavia porcellus
100516386 Sus scrofa
100684053 Canis lupus familiaris
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