anti-Monoamine Oxidase B (MAOB) Antibodies

Zebrafish Monoamine Oxidase B (MAOB) interaction partners

1. Zebrafish MAO (zMAO) exhibits functional properties similar to human hMAO A as well as exhibits its own unique behavior.

2. expression, purification & characterization of zebrafish monoamine oxidase (zMAO) using Pichia pastoris expression system is described; zMAO possesses little differential sensitivity to acetylenic inhibitors than exhibited by either human MAO A & MAO (show MAOA Antibodies) B

3. this study confirm the presence of functionally active MAO in zebrafish brain and other tissues and characterize the neural systems that express MAO and areas of intense activity in the brain.

Human Monoamine Oxidase B (MAOB) interaction partners

1. Our observations provide new information on the genotype-phenotype relations of MAOA (show MAOA Antibodies)/B and EFHC2 (show EFHC2 Antibodies) genes involved in the contiguous deletions of Norrie disease.Based on the case of our observation, contiguous deletion with only one of the MAO (show MAO Antibodies) genes (MAOB) may not cause psychomotor disability, and deletion of EFHC2may not contribute to epilepsy.

2. the mean methylation values of the CpG sites studied in the MAOA (show MAOA Antibodies) gene were related to smoking behavior in women. Similarly, several methylation patterns in the MAOB gene were associated with a smoking history, with each CpG site showing a remarkable sex dependence. Smoking behavior seems to be related to the genetic and epigenetic profile of MAO (show MAO Antibodies) genes, with considerable individual and sex-related differences

3. This study shows that MAO-B levels are increased not only in astrocytes but also in pyramidal neurons in Alzheimer disease brain and also suggests that MAO-B regulates Abeta (show APP Antibodies) production in neurons via gamma-secretase

4. The findings may suggest that MAO-B is an important sensor in iron-stressed neuronal cells.

5. Childhood trauma interacts with haplotypes in COMT (show COMT Antibodies), MAOA (show MAOA Antibodies) and MAOB, increasing risk for OCD.

6. brain protein levels of MAOB are normal or elevated in the three parkinsonian conditions-with MAOB increase generally associated with elevations in levels of astrocyte markers. Brain MAOA (show MAOA Antibodies) concentrations were, somewhat surprisingly, not decreased in Parkinson's disease, Progressive Supranuclear palsy or multiple system atrophy with the exception of the atrophic putamen in MSA (show TPO Antibodies), despite loss of dopamine neurons.

7. MAOA (show MAOA Antibodies) and MAOB variants may contribute to the etiology of Attention deficit hyperactivity disorder (ADHD) in the Indo (show IDO1 Antibodies)-Caucasoid population and could be responsible for higher occurrence of ADHD in the boys.

8. MAOB gene variants are contributing to the etiology of ADHD in the Indo (show IDO1 Antibodies)-Caucasoid population

9. This study suggests that MAOB increases ASD (show ARSD Antibodies) risk in males, possibly through its sex-specific regulatory effect on 5-HT (show DDC Antibodies) metabolism and behavior.

10. These findings suggest an association of platelet MAO-B activity, but a lack of association of MAOB rs1799836 and MAOA (show MAOA Antibodies)-uVNTR, with selected psychotic symptoms in ethnically homogenous veterans with PTSD.

Pig (Porcine) Monoamine Oxidase B (MAOB) interaction partners

1. cloning and characterization of monoamine oxidase A (show MAOA Antibodies) and B genes in pig

Mouse (Murine) Monoamine Oxidase B (MAOB) interaction partners

1. Hydralazine (Hdz) abrogated the degradation of tele (show TCAP Antibodies)-methylhistamine (tMH) catalyzed by monoamine oxidase B (MAO-B) in vitro.

2. Huntington disease (show HTT Antibodies) neural cells exhibit increased Monoamine oxidase-A (show MAOA Antibodies) and Monoamine oxidases-B expression and activity

3. Activity of monoamine oxidase B in the striatum is reduced during the presymptomatic stage, but returns to the control level during the symptomatic stage of Parkinsonism in mice.

4. These findings demonstrate that regulation of monoamine levels by Mao (show MAO Antibodies) activity in beta cells is pivotal for physiological insulin (show INS Antibodies) secretion and that loss of MaoB expression may contribute to the beta cell dysfunction in type 2 diabetes.

5. Monoamine oxidase B deficiency (along with monoamine oxidase A (show MAOA Antibodies)) resulted in an array of abnormalities similar to autism-spectrum disorder.

6. chronic elevations of monoamines, because of the absence of MAO A (show MAOA Antibodies) and MAO B, cause functional alterations that are accompanied with changes in the cellular mechanisms underlying learning and memory.

7. MAO-B is involved in the acute neurotoxicity of MPTP (show PTPN2 Antibodies) in embryonic and newborn mice

8. Data suggest that both IR1 (imidazoline receptor 1 (show NISCH Antibodies)) and IR2/Maob play roles in acquisition of behavioral responses in alcoholism; activation of IR1 (show NISCH Antibodies) and IR2/Maob may serve as molecular targets in prevention (and possibly treatment) of alcoholism.

9. The results of our study further confirms that the dox-inducible astrocytic MAO-B transgenic mouse displays similar age-related behavioral and neuropathological features to other models of Parkinson's disease

10. MAO-B seems to exert a critical role in the development of postoperative and neuropathic pain