anti-Myelin Basic Protein (MBP) Antibodies

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. Additionally we are shipping Myelin Basic Protein Kits (74) and Myelin Basic Protein Proteins (35) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
MBP 4155 P02686
MBP 17196 P04370
MBP 24547 P02688
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Top anti-Myelin Basic Protein Antibodies at antibodies-online.com

Showing 10 out of 198 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Mouse Brain Tissue. 100 μg Log in to see 13 to 16 Days
$314.00
Details
Human Mouse Un-conjugated IHC (fro), IHC (p), WB Staining of white matter in human brain with Mouse anti MBP 2 mL Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated EIA 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Mouse Un-conjugated ELISA, IHC, IHC (p), RIA Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with MBP antibody ABIN462005 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with MBP antibody ABIN462005 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Lane1: Human Brain Tissue; Lane2: Human Spleen Tissue. 100 μg Log in to see 15 to 18 Days
$316.00
Details
Chicken Rat Un-conjugated ELISA, IHC, IHC (p), RIA, WB Anti-Myelin Basic Protein antibody IHC of human myelin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody ABIN1804051 dilution 1:50. 125 μL Log in to see 11 to 14 Days
$484.00
Details
Goat Mouse Un-conjugated ELISA, IHC, IHC (fro), IHC (p), WB Human Brain, Oligodendrocytes (formalin-fixed, paraffin-embedded) stained with MBP antibody ABIN307190 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Anti-Myelin Basic Protein antibody IHC of human brain, oligodendrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. 50 μg Log in to see 11 to 14 Days
$484.00
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with MBP antibody ABIN364503 at 1:100 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with MBP antibody ABIN364503 at 1:100 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μL Log in to see 11 to 14 Days
$639.83
Details

Top referenced anti-Myelin Basic Protein Antibodies

  1. Human Polyclonal MBP Primary Antibody for IHC (p), WB - ABIN548535 : Iester, Vignola, Callegarini, Gimelli, Alpigiani: [18q syndrome with deficiency of myelin basic protein (MBP)]. in La Pediatria medica e chirurgica : Medical and surgical pediatrics 1996 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal MBP Primary Antibody for ICC, IHC - ABIN1078364 : Bleyer, Curths, Dahlmann, Wichmann, Bauer, Moritz, Braun, Knauf, Kaup, Gruber-Dujardin: Morphology and staining behavior of neutrophilic and eosinophilic granulocytes of the common marmoset (Callithrix jacchus). in Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2016 (PubMed)

  3. Rat (Rattus) Polyclonal MBP Primary Antibody for ELISA, WB - ABIN1574105 : Kraitsy, Uecal, Grossauer, Bruckmann, Pfleger, Ropele, Fazekas, Gruenbacher, Patz, Absenger, Porubsky, Smolle-Juettner, Tezer, Molcanyi, Fasching, Schaefer: Repetitive long-term hyperbaric oxygen treatment (HBOT) administered after experimental traumatic brain injury in rats induces significant remyelination and a recovery of sensorimotor function. in PLoS ONE 2014 (PubMed)

More Antibodies against Myelin Basic Protein Interaction Partners

Human Myelin Basic Protein (MBP) interaction partners

  1. the interaction between the HLA-DRB1 (show HLA-DRB1 Antibodies)*1501 allele and MBP (show MBL2 Antibodies) gene may be considered as a predisposing factor in the development and pathogenesis of multiple sclerosis in the case of gene-gene interaction

  2. PAPP-A (show PAPPA Antibodies) and ProMBP are associated with increased risk of death in heart failure patients.

  3. Studied potential use of myelin basic protein (MBP) as a biomarker in CSF (show CSF2 Antibodies) of brain cancer patients. Results suggest that the presence of MBP (show MBL2 Antibodies) in CSF (show CSF2 Antibodies) may be considered as an indicator of the brain tumor development.

  4. t-PA (show PLAT Antibodies) binds to Lys91 in the MBP (show MBL2 Antibodies) NH2-terminal region and PLG (show PLG Antibodies) binds to Lys122 in the MBP (show MBL2 Antibodies) COOH-terminal region. This proximity promotes the activation of PLG (show PLG Antibodies) by t-PA (show PLAT Antibodies).

  5. Specific sites of post-translational modifications in multiple sclerosis patients are localized in two zones of MBP (show MBL2 Antibodies) suggests that these regions may be involved in antigen recognition by the body's immune surveillance machinery

  6. Results provide novel insights into the role of genetic variation within the MBP (show MBL2 Antibodies) gene predicting multiple sclerosis clinical course, both directly and by interaction with known environmental MS risk factors

  7. Deimination of myelin basic protein (MBP) by peptidylarginine deiminase (PAD) prevents its binding to the proteasome and decelerates its degradation by the proteasome in mammalian cells. Potential anticancer drug tetrazole analogue of chloramidine 2, at concentrations greater than 1 microM inhibits the enzymatic activity of PAD in vitro.

  8. This study observed a significantly increased myelin basic protein (MBP) and nuclear distribution protein nudE-like 1 (NDEL1 (show NDEL1 Antibodies)) mRNA levels in FEP patients compared with controls.

  9. myelin basic protein has a role in activating CD4 (show CD4 Antibodies)+ and CD8 (show CD8A Antibodies)+ T lymphocytes in multiple sclerosis

  10. B cells from relapsing-remitting multiple sclerosis patients produce TNFa (show TNF Antibodies) and IL6 (show IL6 Antibodies), and present MBP85-99 peptide

Mouse (Murine) Myelin Basic Protein (MBP) interaction partners

  1. findings suggest that the acetylation and methylation of lysine on MBP are post-translational modifications associated with the neurological disability produced by EAE.

  2. The Mbp(+/-) mice exhibited defects of sensorimotor gating, as evidenced by reduced prepulse-inhibition, and a late-onset catatonia phenotype.

  3. The present study provides evidence for a novel L1-mediated function of MBP in the developing spinal cord and in the injured adult mammalian nervous system that leads to enhanced recovery after acute trauma.

  4. myelin basic protein (MBP) is inhibitory to both primitive neural stem cells and definitive neural stem cells derived colony formation.

  5. CNP (show CNP Antibodies) directly associates with and organizes the actin cytoskeleton, thereby providing an intracellular strut that counteracts membrane compaction by myelin basic protein (MBP).

  6. to further characterize the mechanism regulating mbp transcription, study defined M3 structure/function relationships; multiple M3 regulatory element combinations were found to drive expression in oligodendrocytes and Schwann cells with a minimal 129 bp sequence conferring expression in oligodendrocytes throughout myelin elaboration, maintenance and repair

  7. Results show the expression of sncRNA715 in Schwann cells and its inverse correlation with Mbp mRNA in cultured cells and the sciatic nerve. Its inhibitory effect on MBP was confirmed in differentiating primary Schwann cells.

  8. Results suggest that GAL (show GAL Antibodies) is a regulator of myelination, as demonstrated by MBP synthesis, and may be one of the myelination promoters

  9. Data indicate that 18.5 kDa myelin basic protein (MBP) segment upstream of the primary SH3-ligand is involved in interaction.

  10. Data suggest that prenatal alterations in expression of various fetal brain proteins (including up-regulation of Mbp) are associated with aberrant behavioral characteristics of transgenic mice that model autism-like behavior.

Zebrafish Myelin Basic Protein (MBP) interaction partners

  1. Dynein/dynactin (show DCTN1 Antibodies) is necessary for anterograde transport of Mbp mRNA in oligodendrocytes.

Pig (Porcine) Myelin Basic Protein (MBP) interaction partners

  1. Concentrations of MBP did not increase after injury in all age groups

  2. results provide a detailed picture of the MBP-CaM interaction, including a 3D model of the complex between full-length proteins

  3. MBP-hydrolyzing antibodies may play an important role in multiple sclerosis pathogenesis

Cow (Bovine) Myelin Basic Protein (MBP) interaction partners

  1. Deimination of myelin basic protein (MBP) by peptidylarginine deiminase (PAD) prevents its binding to the proteasome and decelerates its degradation by the proteasome in mammalian cells. Potential anticancer drug tetrazole analogue of chloramidine 2, at concentrations greater than 1 microM inhibits the enzymatic activity of PAD in vitro.

  2. Data suggest that hybrid protein composed of two different Myelin basic protein (MBP) isoforms (TandeMBP) might become a tool for in vitro assays to analyse various protein kinase (show CDK7 Antibodies) activities.

  3. trehalose completely avoid autocatalytic cleavage properties of MBP up to 4 days of incubation at 37 degrees C and pH 7.4.

  4. formation of an imine between inflammatory-derived aldehydes can lead to structural changes in MBP and a decrease in myelin stability

  5. results provide a detailed picture of the MBP-CaM interaction, including a 3D model of the complex between full-length proteins

  6. MBP can induce a dihydrocholesterol-dependent segregation of phases that can be further regulated by the electrolyte concentration in the subphase and the composition (type and proportion) of non-sterol lipids.

  7. Bovine MBP priming reduces expression of Foxp3 (show FOXP3 Antibodies) via nitric oxide in inducible nitric oxide synthase (show NOS2 Antibodies)-deficient mouse T cells.

  8. investigation of bovine myelin basic protein binding to triphosphoinositide

  9. There is a developmental regulation of posttranslationally modified forms of myelin basic protein into specific membrane microdomains.

  10. These results suggest that phospholipids and sulfatide and heparin may function as effective stimulators for autophosphorylation of GSK-3beta and for the GSK-3beta-mediated high phosphorylation of SH-binding proteins, including MBP and tau protein.

Myelin Basic Protein (MBP) Antigen Profile

Protein Summary

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.

Gene names and symbols associated with MBP

  • myelin basic protein (MBP) antibody
  • myelin basic protein (Mbp) antibody
  • myelin basic protein a (mbpa) antibody
  • myelin basic protein (mbp) antibody
  • myelin basic protein L homeolog (mbp.L) antibody
  • C76307 antibody
  • cb274 antibody
  • fj33b11 antibody
  • golli-mbp antibody
  • Hmbpr antibody
  • mbp antibody
  • Mbps antibody
  • MGC115135 antibody
  • mld antibody
  • R75289 antibody
  • shi antibody
  • wu:fj33b11 antibody
  • wu:fq15b02 antibody
  • zgc:136630 antibody

Protein level used designations for MBP

myelin A1 protein , myelin membrane encephalitogenic protein , myelin deficient , shiverer , Golli-Mbp; myelin basic protein , Golli-Mbp; myelin basic protein; myelin basic protein S , MBP S , myelin basic protein Golli-mbp , myelin basic protein S , myelin basic protein , Golli-mbp , 20 kDa microtubule-stabilizing protein , microtubule-stabilizing protein , Myelin A1 protein , Myelin P1 protein

GENE ID SPECIES
4155 Homo sapiens
17196 Mus musculus
24547 Rattus norvegicus
326281 Danio rerio
396217 Gallus gallus
399102 Xenopus laevis
414286 Sus scrofa
455522 Pan troglodytes
476160 Canis lupus familiaris
549346 Xenopus (Silurana) tropicalis
618684 Bos taurus
734401 Xenopus laevis
100174122 Pongo abelii
101109407 Ovis aries
100731253 Cavia porcellus
100344447 Oryctolagus cuniculus
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