N-terminal Asparagine Amidase Proteins
The protein encoded by NTAN1 functions in a step-wise process of protein degradation through the N-end rule pathway.
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N-terminal Asparagine Amidase (NTAN1) (AA 2-310) protein (His tag) Protein
N-terminal Asparagine Amidase (NTAN1) (AA 2-310) protein (His tag) Protein
N-terminal Asparagine Amidase (NTAN1) (AA 1-310) protein (GST tag) Protein
N-terminal Asparagine Amidase (NTAN1) protein (Myc-DYKDDDDK Tag) Protein
N-terminal Asparagine Amidase (NTAN1) (AA 2-310) protein (His tag) Protein
N-terminal Asparagine Amidase (NTAN1) Protein Profile
Protein Summary
The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Gene names and symbols associated with NTAN1
- N-terminal Asn amidase (Ntan1) antibody
- N-terminal asparagine amidase (NTAN1) antibody
- PNAA antibody
- PNAD antibody
Protein level used designations for NTAN1
N-terminal asparagine amidohydrolase , PNAA , PNAD , asparagine-specific N-terminal amidase , protein N-terminal Asn amidase , protein N-terminal asparagine amidohydrolase , protein NH2-terminal asparagine amidohydrolase , protein NH2-terminal asparagine deamidase , protein NTN-amidase
| GENE ID | SPECIES |
|---|---|
| 18203 | Mus musculus |
| 123803 | Homo sapiens |
| 397107 | Sus scrofa |
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