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The protein encoded by NTAN1 functions in a step-wise process of protein degradation through the N-end rule pathway. Additionally we are shipping N-terminal Asparagine Amidase Antibodies (32) and N-terminal Asparagine Amidase Kits (3) and many more products for this protein.
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when embryonic 12-day-old or newborn mice were successively exposed to magnetic fields Ntan1 mRNA was significantly increased
The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
N-terminal asparagine amidohydrolase
, asparagine-specific N-terminal amidase
, protein N-terminal Asn amidase
, protein N-terminal asparagine amidohydrolase
, protein NH2-terminal asparagine amidohydrolase
, protein NH2-terminal asparagine deamidase
, protein NTN-amidase