NDUFA1 Proteins

Protein Summary

The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the 'hydrophobic protein' (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function.

Gene names and symbols associated with NDUFA1

• NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 (Ndufa1) antibody
• NADH:ubiquinone oxidoreductase subunit A1 (Ndufa1) antibody
• NADH:ubiquinone oxidoreductase subunit A1 (NDUFA1) antibody
• NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa (NDUFA1) antibody

• 1810049F12Rik antibody
• CI-MWFE antibody
• MWFE antibody
• RGD1560955 antibody
• ZNF183 antibody

Protein level used designations for NDUFA1

CI-MWFE , NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1 (7.5kD, MWFE) , NADH dehydrogenase 1 alpha subcomplex, 1 , NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 , NADH ubiquinone oxidoreductase subunit MWFE , NADH-ubiquinone oxidoreductase MWFE subunit , complex I-MWFE , Complex I-MWFE , NADH ubiquinone oxidoreductase NDUFA1 , NADH oxidoreductase subunit MWFE , NADH:ubiquinone oxidoreductase (complex 1) , complex I MWFE subunit , type I dehydrogenase