NDUFA5 Proteins

Protein Summary

The human NDUFA5 gene codes for the B13 subunit of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. The high degree of conservation of NDUFA5 extending to plants and fungi indicates its functional significance in the enzyme complex. The protein localizes to the inner mitochondrial membrane as part of the 7 component-containing, water soluble 'iron-sulfur protein' (IP) fraction of complex I, although its specific role is unknown. It is assumed to undergo post-translational removal of the initiator methionine and N-acetylation of the next amino acid. The predicted secondary structure is primarily alpha helix, but the carboxy-terminal half of the protein has high potential to adopt a coiled-coil form. The amino-terminal part contains a putative beta sheet rich in hydrophobic amino acids that may serve as mitochondrial import signal. Related pseudogenes have also been identified on four other chromosomes.

Gene names and symbols associated with NDUFA5

• NADH:ubiquinone oxidoreductase subunit A5 (Ndufa5) antibody
• NADH:ubiquinone oxidoreductase subunit A5 (NDUFA5) antibody
• NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 (Ndufa5) antibody

• 2900002J19Rik antibody
• B13 antibody
• CI-13kB antibody
• CI-13KD-B antibody
• NADHUO antibody
• Show all synonym aliases
• NUFM antibody
• UQOR13 antibody

Protein level used designations for NDUFA5

CI-13kD-B , NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 , NADH ubiquinone oxidoreductase subunit B13 , NADH-ubiquinone oxidoreductase 13 kDa-B subunit , complex I subunit B13 , complex I-13kD-B , Complex I-13KD-B , NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa , complex I 13kDa subunit B , type I dehydrogenase , ubiquinone reductase