anti-Neuronal PAS Domain Protein 4 (NPAS4) Antibodies

NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2\; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM, Mar 2008].. Additionally we are shipping NPAS4 Proteins (6) and NPAS4 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NPAS4 225872 Q8BGD7
NPAS4 266734 Q8CJH6
NPAS4 266743 Q8IUM7
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Top anti-NPAS4 Antibodies at antibodies-online.com

Showing 10 out of 106 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  NPAS4  Sample Type:  Fetal Lung  Lane A:  Primary Antibody  Lane B:  Primary Antibody + Blocking Peptide  Primary Antibody Concentration:  1ug/ml  Peptide Concentration:  5ug/ml  Lysate Quantity:  25ug/lane/Lane  Gel Concentration:  0.12 WB Suggested Anti-NPAS4 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Lung 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of NPAS4 staining in HEK293T cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of NPAS4 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Mouse Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using NPAS4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA, WB Western Blot: Npas4 Antibody [NBP1-68863] - NBP1-68863 (0.3ug/ml) staining of Human Frontal Cortex lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$485.88
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Bat Goat Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$610.50
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Mouse HRP ICC, IF, IHC, WB Western Blot analysis of Rat Brain showing detection of ~90 kDa NPAS4 protein using Mouse Anti-NPAS4 Monoclonal Antibody, Clone S408-79 . Lane 1: MW Ladder. Lane 2: Rat Brain. Load: 20 µg. Block: 2% GE Healthcare Blocker for 1 hour at RT. Primary Antibody: Mouse Anti-NPAS4 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Color Development: ECL solution for 6 min at RT. Predicted/Observed Size: ~90 kDa. Other Band(s): ~60, 45, 40, 38, 25, 20 kDa. 100 μg Log in to see 2 to 3 Days
$422.40
Details
Human Mouse FITC ICC, IF, IHC, WB Western Blot analysis of Rat Brain showing detection of ~90 kDa NPAS4 protein using Mouse Anti-NPAS4 Monoclonal Antibody, Clone S408-79 . Lane 1: MW Ladder. Lane 2: Rat Brain. Load: 20 µg. Block: 2% GE Healthcare Blocker for 1 hour at RT. Primary Antibody: Mouse Anti-NPAS4 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Color Development: ECL solution for 6 min at RT. Predicted/Observed Size: ~90 kDa. Other Band(s): ~60, 45, 40, 38, 25, 20 kDa. 100 μg Log in to see 2 to 3 Days
$426.80
Details
Human Mouse Alkaline Phosphatase (AP) ICC, IF, IHC, WB Western Blot analysis of Rat Brain showing detection of ~90 kDa NPAS4 protein using Mouse Anti-NPAS4 Monoclonal Antibody, Clone S408-79 . Lane 1: MW Ladder. Lane 2: Rat Brain. Load: 20 µg. Block: 2% GE Healthcare Blocker for 1 hour at RT. Primary Antibody: Mouse Anti-NPAS4 Monoclonal Antibody  at 1:1000 for 16 hours at 4°C. Secondary Antibody: Goat Anti-Mouse IgG: HRP at 1:200 for 1 hour at RT. Color Development: ECL solution for 6 min at RT. Predicted/Observed Size: ~90 kDa. Other Band(s): ~60, 45, 40, 38, 25, 20 kDa. 100 μg Log in to see 2 to 3 Days
$429.00
Details

Top referenced anti-NPAS4 Antibodies

  1. Cow (Bovine) Polyclonal NPAS4 Primary Antibody for WB - ABIN2779719 : Ooe, Saito, Mikami, Nakatuka, Kaneko: Identification of a novel basic helix-loop-helix-PAS factor, NXF, reveals a Sim2 competitive, positive regulatory role in dendritic-cytoskeleton modulator drebrin gene expression. in Molecular and cellular biology 2003 (PubMed)
    Show all 2 Pubmed References

  2. Mouse (Murine) Polyclonal NPAS4 Primary Antibody for ICC, IF - ABIN4235495 : Wakasaya, Kawarabayashi, Watanabe, Yamamoto-Watanabe, Takamura, Kurata, Murakami, Abe, Yamada, Wakabayashi, Sasaki, Westaway, Hyslop, Matsubara, Shoji: Factors responsible for neurofibrillary tangles and neuronal cell losses in tauopathy. in Journal of neuroscience research 2011 (PubMed)

More Antibodies against NPAS4 Interaction Partners

Mouse (Murine) Neuronal PAS Domain Protein 4 (NPAS4) interaction partners

  1. ectopic expression of miR (show MLXIP Antibodies)-744 and miR (show MLXIP Antibodies)-224 during neural differentiation resulted in downregulation of endogenous Npas4 expression.

  2. Using a series of behavioral, molecular, pharmacological and genetic approaches in mice, study shows that deficiency in Npas4 affects adolescent expression of multiple markers of GABAergic transmission in the PFC (show CFP Antibodies), including parvalbumin (show PVALB Antibodies) and GAD67 (show GAD1 Antibodies), in a sex-specific manner. Abnormal pattern of expression of GABAergic markers is associated with sex-specific and age-dependent cognitive and emotional impairments.

  3. The findings of this study suggest that Npas4 may be involved in post-stroke psychiatric changes related to anxiety ad sociability.

  4. NPAS4 is expressed in endothelial cells, regulates VE-cadherin (show CDH5 Antibodies) expression and regulates sprouting angiogenesis.

  5. These findings suggest that 11beta-HSD1 (show HSD11B1 Antibodies) may contribute to the decline in Npas4 and Arc (show NOL3 Antibodies) mRNA levels associated with memory impairment during ageing

  6. beta cell cytotoxicity of the calcineurin inhibitor (show RCAN1 Antibodies) and immunosuppressant tacrolimus (FK-506) was prevented by Npas4 overexpression.

  7. Results suggest that transcription of the Npas4 gene is downregulated by stress through DNA methylation (show HELLS Antibodies) of its promoter

  8. induction of Npas4 identifies the area influenced by cortical spreading depression propagation.

  9. Cortex activation by sensory conditioning was found to upregulate the expression of both Npas4 and c-Fos.

  10. Data showed that differential levels of Npas4 expression in the brain may regulate anxiety, depression and cognition related disorders.

Human Neuronal PAS Domain Protein 4 (NPAS4) interaction partners

  1. NPAS4 is expressed in endothelial cells, regulates VE-cadherin (show CDH5 Antibodies) expression and regulates sprouting angiogenesis.

  2. This review summarizes the current knowledge of the roles that Npas4 may play in neuroinflammation and ischemia. [review]

  3. we provide the first evidence that Npas4 is expressed during embryonic development and that it may have a developmental role that is unrelated to its function in the adult brain

  4. These results provide insight into the mechanisms of NPAS4/ARNT (show ARNT Antibodies) dimerisation and transcriptional activation.

  5. a novel NXF signaling system on neural gene promoter may be a molecular target of the adverse effects of Sim2 (show SIM2 Antibodies) in the mental retardation of Down's syndrome

Zebrafish Neuronal PAS Domain Protein 4 (NPAS4) interaction partners

  1. NPAS4 is expressed in endothelial cells, regulates VE-cadherin (show CDH5 Antibodies) expression and regulates sprouting angiogenesis.

NPAS4 Antigen Profile

Protein Summary

NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2\; MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004

Gene names and symbols associated with NPAS4

  • neuronal PAS domain protein 4 (Npas4) antibody
  • neuronal PAS domain protein 4 (NPAS4) antibody
  • neuronal PAS domain protein 4a (npas4a) antibody
  • neuronal PAS domain protein 4 (npas4) antibody
  • neuronal PAS domain-containing protein 4 (Tsp_02837) antibody
  • bHLHe79 antibody
  • Le-PAS antibody
  • MGC146621 antibody
  • npas4 antibody
  • NXF antibody
  • PASD10 antibody
  • wu:fj52d04 antibody
  • zgc:136764 antibody

Protein level used designations for NPAS4

HLH-PAS transcription factor NXF , bHLH-PAS type transcription factor NXF , limbic-enhanced PAS protein , neuronal PAS domain-containing protein 4 , neuronal PAS4 , bHLH PAS type transcription factor NXF , PAS domain-containing protein 10 , class E basic helix-loop-helix protein 79 , neuronal PAS domain protein 4 , neuronal PAS domain-containing protein 4-like

GENE ID SPECIES
225872 Mus musculus
266734 Rattus norvegicus
266743 Homo sapiens
466676 Pan troglodytes
483711 Canis lupus familiaris
714161 Macaca mulatta
724016 Danio rerio
780368 Xenopus (Silurana) tropicalis
781497 Bos taurus
10899621 Trichinella spiralis
100029618 Monodelphis domestica
100052469 Equus caballus
100359105 Oryctolagus cuniculus
100397060 Callithrix jacchus
100442686 Pongo abelii
100481488 Ailuropoda melanoleuca
100520174 Sus scrofa
100593820 Nomascus leucogenys
100715310 Cavia porcellus
101113970 Ovis aries
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