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Nischarin Proteins

NISCH encodes a nonadrenergic imidazoline-1 receptor protein that localizes to the cytosol and anchors to the inner layer of the plasma membrane.

6 results:

Nischarin (NISCH) (AA 2-1504) protein (His tag) Protein

NISCH Origin: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3094087
$14,592.92
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 70 Business Days

Nischarin (NISCH) (AA 1-1593) protein (His tag) Protein

NISCH Origin: Mouse Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3135991
$14,592.92
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 70 Business Days

Nischarin (NISCH) (AA 1246-1346) protein (His tag,GST tag) Protein

NISCH Origin: Human Source: Escherichia coli (E. coli) Recombinant > 95 % IP, SDS, ELISA, WB
Catalog No. ABIN1980700
$320.00
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 15 to 18 Business Days

Nischarin (NISCH) (AA 1246-1345) protein (GST tag) Protein

NISCH Origin: Human Source: Wheat germ Recombinant AP, AA, ELISA, WB
Catalog No. ABIN1312597
$414.29
Plus shipping costs $45.00 and $24.00 dry ice
10 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days

Nischarin (NISCH) (AA 1335-1435) protein (His tag,GST tag) Protein

NISCH Origin: Mouse Source: Escherichia coli (E. coli) Recombinant > 95 % IP, SDS, ELISA, WB
Catalog No. ABIN1980701
$486.00
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 15 to 18 Business Days

Nischarin (NISCH) protein (Myc-DYKDDDDK Tag) Protein

NISCH Origin: Human Source: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2727329
$888.80
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping Shipping to: United States
Will be delivered in 11 Business Days
  • Type Protein
    • Protein
  • Target Nischarin (NISCH)
    • Nischarin (NISCH)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Growth Hormone 1 (GH1)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Lipoyl synthase lipA
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Leptin (LEP)
    • Interleukin 8 (IL8)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • Hemoglobin, alpha 1 (HBA1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • Prolactin (PRL)
    • Interleukin 13 (IL13)
    • CD40 Ligand (CD40LG)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Interleukin 15 (IL15)
    • Porphobilinogen Deaminase (HEMC)
    • beta-2-Microglobulin (B2M)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Adiponectin (ADIPOQ)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Interleukin 33 (IL33)
    • Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1)
  • Application
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Immunoprecipitation (IP)
    • Crystallization (Crys)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Protein Interaction (PI)
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
  • Images available
  • Host
    • Escherichia coli (E. coli)
    • Insect Cells
    • HEK-293 Cells
    • Wheat germ
  • Binding Specificity
    • AA 1-1593
    • AA 1246-1345
    • AA 1246-1346
    • AA 1335-1435
    • AA 2-1504
  • Conjugate
    • Un-conjugated
    • His tag
    • His tag,GST tag
    • GST tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid

Nischarin (NISCH) Protein Profile

Protein Summary

This gene encodes a nonadrenergic imidazoline-1 receptor protein that localizes to the cytosol and anchors to the inner layer of the plasma membrane. The orthologous mouse protein has been shown to influence cytoskeletal organization and cell migration by binding to alpha-5-beta-1 integrin. In humans, this protein has been shown to bind to the adapter insulin receptor substrate 4 (IRS4) to mediate translocation of alpha-5 integrin from the cell membrane to endosomes. Expression of this protein was reduced in human breast cancers while its overexpression reduced tumor growth and metastasis\; possibly by limiting the expression of alpha-5 integrin. In human cardiac tissue, this gene was found to affect cell growth and death while in neural tissue it affected neuronal growth and differentiation. Alternative splicing results in multiple transcript variants encoding differerent isoforms. Some isoforms lack the expected C-terminal domains of a functional imidazoline receptor.

Gene names and symbols associated with Nischarin Proteins (NISCH)

  • nischarin (NISCH) antibody
  • nischarin (Cyan7822_6841) antibody
  • nischarin S homeolog (nisch.S) antibody
  • nischarin (nisch) antibody
  • nischarin (Nisch) antibody
  • 1200007D05Rik antibody
  • 3202002H23Rik antibody
  • AW494485 antibody
  • hIRAS antibody
  • I-1 antibody
  • IR1 antibody
  • IRAS antibody
  • NISCH antibody

Protein level used designations for Nischarin Proteins (NISCH)

nischarin , nischarin-like , I1R , IR1 , imidazoline receptor 1 , imidazoline receptor I-1-like protein , imidazoline-1 receptor , I-1 receptor candidate protein , imidazoline receptor I-1 , I1R candidate protein , imidazoline receptor antisera selected

GENE ID SPECIES
415893 Gallus gallus
476594 Canis lupus familiaris
515009 Bos taurus
745886 Pan troglodytes
9736308 Cyanothece sp. PCC 7822
100036978 Xenopus laevis
100060179 Equus caballus
100156417 Sus scrofa
100170568 Xenopus (Silurana) tropicalis
100346537 Oryctolagus cuniculus
100391522 Callithrix jacchus
100457907 Pongo abelii
100540291 Meleagris gallopavo
100559383 Anolis carolinensis
100582208 Nomascus leucogenys
64652 Mus musculus
306255 Rattus norvegicus
11188 Homo sapiens
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