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Nischarin Proteins

(Nischarin (NISCH))

This gene encodes a nonadrenergic imidazoline-1 receptor protein that localizes to the cytosol and anchors to the inner layer of the plasma membrane. The orthologous mouse protein has been shown to influence cytoskeletal organization and cell migration by binding to alpha-5-beta-1 integrin. In humans, this protein has been shown to bind to the adapter insulin receptor substrate 4 (IRS4) to mediate translocation of alpha-5 integrin from the cell membrane to endosomes. Expression of this protein was reduced in human breast cancers while its overexpression reduced tumor growth and metastasis\; possibly by limiting the expression of alpha-5 integrin. In human cardiac tissue, this gene was found to affect cell growth and death while in neural tissue it affected neuronal growth and differentiation. Alternative splicing results in multiple transcript variants encoding differerent isoforms. Some isoforms lack the expected C-terminal domains of a functional imidazoline receptor. [provided by RefSeq, Jan 2013].

recommended

Nischarin Protein (NISCH) (AA 1-1593) (His tag) (ABIN7564238)

custom-made NISCH Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

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recommended

Nischarin Protein (NISCH) (GST tag) (ABIN7578460)

NISCH Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, WB, ELISA

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NISCH Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, Imm, PC

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Nischarin Proteins by Grade

Find Nischarin Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Nischarin Proteins by Origin

Find Nischarin Proteins for a variety of species such as anti-Human Nischarin, anti-Mouse Nischarin. The species listed below are among those available. Click on a link to go to the corresponding products.

Nischarin Proteins by Source

Here you will find Nischarin Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Nischarin Proteins by Protein Type

Here you can find Nischarin Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

Nischarin Proteins by Application

Find Nischarin Proteins validated for a specific application such as SDS, WB, Imm, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Nischarin Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

Nischarin Protein (NISCH) (AA 1-1593) (His tag)

Reactivity Mouse

Source HEK-293 Cells

Validations

Cat. No. ABIN7564238

Quantity 1 mg

Datasheet Datasheet

Nischarin Protein (NISCH) (GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7578460

Quantity 100 μg

Datasheet Datasheet

Nischarin Protein (NISCH) (AA 1246-1346) (His tag,GST tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7389638

Quantity 100 μg

Datasheet Datasheet

Nischarin Protein (NISCH) (AA 1335-1435) (His tag,GST tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7415323

Quantity 100 μg

Datasheet Datasheet

Nischarin Protein (NISCH) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2727329

Quantity 20 μg

Datasheet Datasheet

Aliases for Nischarin Proteins

nischarin (NISCH) Proteins
nischarin (Cyan7822_6841) Proteins
nischarin S homeolog (nisch.S) Proteins
nischarin (nisch) Proteins
nischarin (Nisch) Proteins
1200007D05Rik Proteins
3202002H23Rik Proteins
AW494485 Proteins
hIRAS Proteins
I-1 Proteins
IR1 Proteins
IRAS Proteins
NISCH Proteins

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Nischarin Proteins by Grade

Nischarin Proteins by Origin

Nischarin Proteins by Source

Nischarin Proteins by Protein Type

Nischarin Proteins by Application

Popular Nischarin Proteins

Aliases for Nischarin Proteins

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