anti-Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) Antibodies

NFE2L1 encodes a protein that is involved in globin gene expression in erythrocytes. Additionally we are shipping NFE2L1 Kits (8) and NFE2L1 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NFE2L1 4779 Q14494
NFE2L1 18023 Q61985
NFE2L1 360610  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-NFE2L1 Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-NFE2L1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Spleen 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: NFE2L1 Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: NFE2L1 Sample Tissue: Human HepG2 Whole Cell Antibody Dilution: 1ug/ml WB Suggested Anti-NFE2L1 Antibody Titration: 1.0 ug/ml Positive Control: THP-1 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB NFE2L1 Antibody (C-term) (ABIN654881) western blot analysis in mouse lung tissue lysates (35 µg/lane). This demonstrates the NFE2L1 antibody detected the NFE2L1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis in mouse lung tissue lysates (35ug/lane) using NFE2L1  Antibody (C-term). This demonstrates this antibody detected the NFE2L1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Cow Rabbit Un-conjugated WB NFE2L1 (nuclear factor (erythroid-derived 2)-like 1) Antibody (against the middle region of NFE2L1) (50ug) validated by WB using Jurkat cell lysate at 0.2-1 ug/ml. 100 μL Log in to see 2 to 3 Days
$319.00
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, WB   100 μL Log in to see Available
$181.73
Details
Human Mouse Un-conjugated WB Western blot analysis of extracts of various cells, using NRF1 antibody. Western blot analysis of extracts of various cell lines, using NRF1 antibody (ABIN4905385) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Mouse IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s. 100 μL Log in to see 11 to 13 Days
$433.51
Details

More Antibodies against NFE2L1 Interaction Partners

Human Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) interaction partners

  1. Data show that Nrf1 can adopt several topologies within membranes that are determined by its NTD.

  2. Fbw7 as a regulator of Nrf1 expression and reveal a novel function of Fbw7 in cellular stress response.

  3. results indicate a novel role of Nrf1 in UVB-induced DNA damage repair and suggest Nrf1 as a tumor suppressor in the skin

  4. Data indicate both Nrf1a and Nrf1b isoforms transcripts were detected in different mouse and human cell lines, and in various mouse tissues.

  5. Nrf1 knockout resulted in the increased expression of GCLC and GCLM in human bronchial epithelial (HBE1) cells.

  6. while Nrf2 is crucial for MRE/ARE-mediated transcription in response to copper, Nrf1 may activate MT-1 expression by a mechanism different from that Nrf2 employs.

  7. Nrf1 physically interacts with androgen receptor and enhances it's DNA-binding activity, suggesting that the p65-Nrf1 isoform is a potential androgen receptor coactivator.

  8. The treatment with E2, Res, or VC significantly increased mRNA and protein expression levels of Nrf1.

  9. The results indicate that Nrf1 is a transcriptional activator of Herpud1 expression during ER stress, and they suggest Nrf1 is a key player in the regulation of the ER stress response in cells.

  10. This review outlines Nrf1 structure, function, regulation and its links to insulin resistance, diabetes and inflammation.

  11. Importantly, Nrf1 activity is positively and/or negatively regulated by distinct doses of proteasome and calpain inhibitors

  12. Together with molecular expression results, the authors thus suppose requirement of Nrf1alpha (and major derivates) for gene regulatory mechanisms repressing cancer cell process and malignant behaviour.

  13. These results uncover a new regulatory mechanism that USP15 activates Nrf1 against the beta-TrCP inhibition to maintain proteostasis.

  14. Here the authors show that the aspartyl protease DNA-damage inducible 1 homolog 2 (DDI2) is required to cleave and activate Nrf1.

  15. Nrf1 is regulated by O-GlcNAc transferase.

  16. our investigation shows that the ER membrane protein TCF11/Nrf1 is an essential component of the cellular stress response mechanism. In response to cytotoxic stress, TCF11/Nrf1 is retrotranslocated and transferred to the nucleus where it induces proteasome subunit expression via binding to the ARE region of the relevant promoter.

  17. Data uncover an unexpected role for p97 in activation of transcription factor Nrf1 by relocalizing it from the endoplasmic reticulum lumen to the cytosol.

  18. Nrf1 is negatively regulated by its O-GlcNAcylation status that depends on the glucose concentrations

  19. A proteasome inhibitor-stimulated Nrf1 protein-dependent compensatory increase in proteasome subunit gene expression reduces polycomb group protein level

  20. The study identifies casein kinase 2 as an NRF1-binding protein and finds that the knockdown of casein kinase 2 enhances the NRF1-dependent expression of the proteasome subunit genes.

Mouse (Murine) Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1) interaction partners

  1. Mechanistic studies revealed that Nfe2l1 deficiency may disturb the expression of lipolytic genes in adipocytes, leading to adipocyte hypertrophy followed by inflammation, pyroptosis, and insulin resistance.

  2. our investigation shows that the ER membrane protein TCF11/Nrf1 is an essential component of the cellular stress response mechanism. In response to cytotoxic stress, TCF11/Nrf1 is retrotranslocated and transferred to the nucleus where it induces proteasome subunit expression via binding to the ARE region of the relevant promoter.

  3. Deficiency of long isoforms of Nfe2l1 in pancreatic beta-cells increased susceptibility to acute arsenite-induced cytotoxicity by promoting arsenic biotransformation and intracellular MMA levels.

  4. Nrf1 is negatively regulated by its O-GlcNAcylation status that depends on the glucose concentrations

  5. Denervation induced proteasomal activation via NFE2L1 nuclear translocation in control mice

  6. This stduy identify the bZIP transcription factor Nfe2l1 and demonstrate that it promotes glial fate under direct Sox9 regulatory control.

  7. The study identifies casein kinase 2 as an NRF1-binding protein and finds that the knockdown of casein kinase 2 enhances the Nrf1-dependent expression of the proteasome subunit genes.

  8. Nrf1 plays an integral role in the maintenance of proteasome function in hepatocytes and in the prevention of liver steatosis development.

  9. findings suggest that nuclear-related factor erythroid 2 transcription factor (Nrf1) may play a role in maintaining genomic integrity, and that Nrf1 dysregulation may induce tumorigenesis

  10. The transcription factor, TCF11, is at the crossroads of oxidative stress and the ubiquitin proteasome system.

  11. Data show that nuclear factor erythroid-derived 2-related factor 1 (Nrf1), but not the related Nrf2, is necessary for induced proteasome gene transcription in mouse embryonic fibroblasts.

  12. the first in vivo experimental evidence that NFE2L1 produced by osteoblasts is involved in regulating osterix expression, osteoblast differentiation, and bone formation

  13. may promote cell survival by maintaining redox balance and protecting embryonic hepatocytes from TNF-mediated apoptosis during development

  14. the physical interaction between Nrf1 and C/EBPbeta provide a novel mechanism for the transcriptional regulation of DSPP in odontoblasts.

  15. Nrf1 is normally targeted to the endoplasmic reticulum membrane, and endoplasmic reticulum stress may play a role in modulating Nrf1 function as a transcriptional activator

  16. Activation of ARE-driven genes by Nrf1 was negatively controlled by the 155-AA N-terminal domain through its ability to direct Nrf1 to the endoplasmic reticulum.

  17. Arachidonic acid modulated osterix expression by a mechanism involving Nrf1 nuclear translocation and Nrf1 binding to oxidant response elements to activate genes in cell differentiation.

  18. The amino- and carboxyl-terminal regions are required for correct membrane orientation of Nrf1, as deletion of residues 2-10 or 23-30 greatly increase its association with the endoplasmic reticulum and the extent to which it is glycosylated.

NFE2L1 Antigen Profile

Protein Summary

This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene, NFE2L1, and for 'nuclear respiratory factor 1' which has an official symbol of NRF1.

Gene names and symbols associated with NFE2L1

  • nuclear factor, erythroid 2 like 1 (NFE2L1) antibody
  • nuclear factor, erythroid derived 2,-like 1 (Nfe2l1) antibody
  • nuclear factor, erythroid 2-like 1 (Nfe2l1) antibody
  • nuclear factor, erythroid 2 like 1 (Nfe2l1) antibody
  • nuclear factor, erythroid 2 like 1 S homeolog (nfe2l1.S) antibody
  • nuclear factor, erythroid 2-like 1a (nfe2l1a) antibody
  • AA408798 antibody
  • AW212678 antibody
  • LCR-F1 antibody
  • Lcrf1 antibody
  • nfe2l1 antibody
  • NRF1 antibody
  • TCF-11 antibody
  • TCF11 antibody

Protein level used designations for NFE2L1

NF-E2-related factor 1 , NFE2-related factor 1 , TCF-11 , locus control region-factor 1 , nuclear factor (erythroid-derived 2)-like 1 , nuclear factor erythroid 2-related factor 1 , nuclear factor, erythroid derived 2, like 1 , transcription factor 11 (basic leucine zipper type) , transcription factor HBZ17 , transcription factor LCR-F1 , nuclear factor erythroid 2-like 1 , nuclear factor, erythroid 2 like 1 S homeolog , nuclear factor, erythroid 2-like 1 , nrf1a , nuclear factor, erythroid derived 2,-like 1 , nuclear factor, erythroid derived 2,-like 1a , nuclear factor-like 1 , nuclear factor-like 1a protein

GENE ID SPECIES
4779 Homo sapiens
18023 Mus musculus
360610 Rattus norvegicus
417987 Gallus gallus
534582 Bos taurus
100172747 Pongo abelii
100716712 Cavia porcellus
379703 Xenopus laevis
405781 Danio rerio
Selected quality suppliers for anti-NFE2L1 (NFE2L1) Antibodies
Did you look for something else?