OTUD5 Proteins
OTUD5 encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily.
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OTU Domain Containing 5 (OTUD5) (AA 1-571) protein (His tag) Protein
OTU Domain Containing 5 (OTUD5) (AA 1-566) protein (His tag) Protein
OTU Domain Containing 5 (OTUD5) (AA 1-542) protein (GST tag) Protein
OTU Domain Containing 5 (OTUD5) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein
OTU Domain Containing 5 (OTUD5) (AA 1-566) protein (His tag) Protein
OTUD5 Protein Profile
Protein Summary
This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene names and symbols associated with OTUD5
- OTU deubiquitinase 5 (OTUD5) antibody
- OTU domain containing 5 (Otud5) antibody
- OTU deubiquitinase 5 (Otud5) antibody
- OTU deubiquitinase 5a (otud5a) antibody
- OTU deubiquitinase 5 L homeolog (otud5.L) antibody
- OTU deubiquitinase 5b (otud5b) antibody
- AA407879 antibody
- AI553596 antibody
- BB114028 antibody
- DUBA antibody
- DXImx46e antibody
- otud5 antibody
- Sfc7 antibody
- si:bz30i22.1 antibody
- si:rp71-30i22.1 antibody
- wu:fi28a06 antibody
- zgc:100839 antibody
- zgc:154072 antibody
Protein level used designations for OTUD5
OTU domain-containing protein 5 , deubiquinating enzyme A , deubiquitinating enzyme A , DUBA , OTU domain containing 5 , OTU domain-containing protein 5-A , LOW QUALITY PROTEIN: OTU domain-containing protein 5 , OTU deubiquitinase 5b , OTU domain containing 5b
GENE ID | SPECIES |
---|---|
55593 | Homo sapiens |
54644 | Mus musculus |
363452 | Rattus norvegicus |
480911 | Canis lupus familiaris |
539145 | Bos taurus |
555459 | Danio rerio |
737927 | Pan troglodytes |
494714 | Xenopus laevis |
100732793 | Cavia porcellus |
445146 | Danio rerio |
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