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OLR1 encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. Additionally we are shipping OLR1 Kits (86) and OLR1 Proteins (29) and many more products for this protein.
Showing 10 out of 242 products:
Human Polyclonal OLR1 Primary Antibody for IF (p), IHC (p) - ABIN676988
Wu, Tang, Jiang, Li, Jiang, Liu: PCSK9 siRNA inhibits HUVEC apoptosis induced by ox-LDL via Bcl/Bax-caspase9-caspase3 pathway. in Molecular and cellular biochemistry 2011
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Human Monoclonal OLR1 Primary Antibody for BR, CyTOF - ABIN5012947
Vilser, Hueller, Nowicki, Hmeidan, Blumenauer, Spanel-Borowski et al.: The variable expression of lectin-like oxidized low-density lipoprotein receptor (LOX-1) and signs of autophagy and apoptosis in freshly harvested human granulosa cells depend on gonadotropin dose, ... in Fertility and sterility 2010
Show all 4 Pubmed References
Human Polyclonal OLR1 Primary Antibody for IHC (fro), FACS - ABIN2475355
Sawamura, Kume, Aoyama, Moriwaki, Hoshikawa, Aiba, Tanaka, Miwa, Katsura, Kita, Masaki: An endothelial receptor for oxidized low-density lipoprotein. in Nature 1997
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Human Polyclonal OLR1 Primary Antibody for IF, ELISA - ABIN2475353
Chen, Masaki, Sawamura: LOX-1, the receptor for oxidized low-density lipoprotein identified from endothelial cells: implications in endothelial dysfunction and atherosclerosis. in Pharmacology & therapeutics 2002
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Human Polyclonal OLR1 Primary Antibody for IF, ELISA - ABIN2475354
Li, Liu, Chen, Sawamura, Mehta: LOX-1, an oxidized LDL endothelial receptor, induces CD40/CD40L signaling in human coronary artery endothelial cells. in Arteriosclerosis, thrombosis, and vascular biology 2003
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Mouse (Murine) Monoclonal OLR1 Primary Antibody for FACS - ABIN4897693
Biedroń, Konopiński, Marcinkiewicz, Józefowski: Oxidation by neutrophils-derived HOCl increases immunogenicity of proteins by converting them into ligands of several endocytic receptors involved in antigen uptake by dendritic cells and macrophages. in PLoS ONE 2015
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Human Polyclonal OLR1 Primary Antibody for ELISA - ABIN1997147
Hinagata, Kakutani, Fujii, Naruko, Inoue, Fujita, Mehta, Ueda, Sawamura: Oxidized LDL receptor LOX-1 is involved in neointimal hyperplasia after balloon arterial injury in a rat model. in Cardiovascular research 2005
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Human Monoclonal OLR1 Primary Antibody for FACS - ABIN4897702
Lara-Guzmán, Gil-Izquierdo, Medina, Osorio, Álvarez-Quintero, Zuluaga, Oger, Galano, Durand, Muñoz-Durango: Oxidized LDL triggers changes in oxidative stress and inflammatory biomarkers in human macrophages. in Redox biology 2017
Human Polyclonal OLR1 Primary Antibody for ICC, IF - ABIN4331395
Chen, Qiu, Lin, Nam, Ogbu-Nwobodo, Archibald, Joslin, Wun, Sawamura, Green: Lectin-like oxidized low-density lipoprotein receptor (LOX-1) in sickle cell disease vasculopathy. in Blood cells, molecules & diseases 2016
Human Polyclonal OLR1 Primary Antibody for ELISA, WB - ABIN4331396
Shi, Cosentino, Camici, Akhmedov, Vanhoutte, Tanner, Lüscher: Oxidized low-density lipoprotein activates p66Shc via lectin-like oxidized low-density lipoprotein receptor-1, protein kinase C-beta, and c-Jun N-terminal kinase kinase in human endothelial cells. in Arteriosclerosis, thrombosis, and vascular biology 2011
ox-LDL and LOX-1 increase due to subarachnoid hemorrhage and they may play a role in the pathogenesis of vasospasm.
LOX (show LOX Antibodies) and LOXL2 (show LOXL2 Antibodies) play an important role in wound healing after glaucoma filtration surgery. Targeting LOXL2 (show LOXL2 Antibodies) with an inhibitory monoclonal antibody (GS-607601) had a broader efficacy than targeting LOX (show LOX Antibodies), reducing angiogenesis and inflammation, and fibrosis.
Angiotensin (1-7) inhibited LOX-1 expression and diminished Ang II (show AGT Antibodies)-mediated inflammation in endothelial cells
Elevated LOX-1 expression and inflammatory responses are induced in hypercholesterolemic rabbits by Chlamydia pneumoniae GroEL1 heat shock protein.
Early treatment with fluvastatin had a crucial endothelial protective effect by down-regulating LOX-1 expression level in atherosclerotic arteries in early atherosclerosis.
LOX-1 expression appears to be closely associated with tissue factor (show F3 Antibodies) expression, apoptotic events and morphological vulnerability in atherosclerotic lesions
high LOX-1 expression in pancreatic cancer tissues is indicative for the occurrence of lymph node metastases, high TNM (show ODZ1 Antibodies) stages and a poor prognosis.
lincRNAp21 is a major mediator of oxLDLinduced apoptosis and expression of LOX1 in human vascular endothelial cells, and acts via activation of PKCdelta (show PKCd Antibodies).
this study shows that LOX-1 is involved in IL-1beta (show IL1B Antibodies) production and extracellular matrix breakdown in dental peri (show PLIN1 Antibodies)-implantitis
Results showed that the scFv with N-terminal fusing peptides proteins demonstrated increased LOX-1-binding activity without decrease in stability. These findings will help increase the application efficacy of LOX-1 targeting scFv in LOX-1-based therapy
The serum sLOX-1 level was higher in patients with large artery atherosclerotic stroke, and it was an independent predictor of functional outcome in patients with large artery atherosclerotic ischemic stroke.
LOX-1 has a role in atherogenesis and tumorigenesis as a potential link in these diseases [review]
the rs1050283 T allele of LOX-1 is strongly associated with an increased risk for atherosclerotic cerebral infarction in a Chinese population, which also affects levels of LOX-1 and sLOX-1
data revealed that miR (show MLXIP Antibodies)-let-7g exhibits anti-atherosclerotic activity, at least partially by targeting the LOX-1 signaling pathway.
High LOX1 expression is associated with colorectal cancer.
Increased LOX-1 expression in endothelial cells is potentially involved in the pathogenesis of sickle cell disease vasculopathy
hyperoside inhibits oxLDL-induced LOX-1 expression, ERK (show EPHB2 Antibodies) activation, and cell proliferation through the oxLDL-LOX-1-ERK (show EPHB2 Antibodies) pathway in VSMCs.
At low oxLDL levels LOX-1 activates the protective Oct-1/SIRT1 pathway, while at higher levels of the lipoprotein switches to the thrombogenic ERK1/2 pathway.
Adiponectin, TNF-alpha (show TNF Antibodies), and LOX-1 exert complex regulatory effects on the coronary microvascular endothelial function in atherosclerotic ApoE (show APOE Antibodies) knockout mice.
LOX-1 in cardiomyocytes plays an important role in the pathology of doxorubicin-induced cardiomyopathy. LOX-1 deletion altered the LOX-1-related signaling pathway, which led to improvements in cardiac function, myocardial inflammation, fibrosis and degenerative changes after DOX treatment.
Therefore we concluded that HNG (show NRGN Antibodies) could inhibit ox-LDL-induced macrophage-derived foam cell formation, which occurs because of a decrease in lipid uptake and an increase in cholesterol efflux from macrophage cells.
The study indicated that the LOX-1/ox-LDL system in chondrocytes plays a role in the pathogenesis of age-related knee knee osteoarthritis, which is potentially a target for preventing knee osteoarthritis progression.
We demonstrated that varenicline upregulates expression of LOX-1 and CD36 (show CD36 Antibodies) significantly through alpha7 nAChR (show CHRNA7 Antibodies), thereby promoting oxLDL uptake in macrophages.
this study shows that LOX-1 can regulate inflammation through regulation of generation of reactive oxygen species in in Aspergillus fumigatus keratitis
The in vitro and in vivo models revealed that lipid metabolism disorder and FK506 caused oxidative stress and a fibrogenic response. In addition, decreased levels of LOX1 markedly reduced the levels of TGFb1 (show TGFB1 Antibodies) in the in vitro model.
Endothelial LOX-1 overexpression in an atherosclerosis-prone LDL receptor (show LDLR Antibodies) knockout mice impairs endothelial function, proving its importance in the development of atherosclerosis.
bta-miR (show MYLIP Antibodies)-370 has a negative regulatory effect on the OLR1 gene at both the gene and protein expression levels and has a role in lipid metabolism in bovine adipocytes
Overexpression of LOX-1 leads to the attenuation of protective autophagy response in aortic endothelial cells.
These results imply that the 3' UTR (show UTS2R Antibodies) SNP of the OLR1 gene is a strong candidate marker for selection in cattle breeding programs.
Our data indicate that blocking the LOX-1 receptor signal pathway might be a promising way to improve steroid hormone concentrations in metabolically highly active female mammals
In the present study, we show that inhibition of LOX-1 leads to a rearrangement of ceramide from the basal membrane toward the Golgi apparatus
The downregulation of eNOS (show NOS3 Antibodies) by ox-low-density lipoprotein, as driven by LOX-1-mediated endoplasmic stress, is associated with the PI3K-Akt (show AKT1 Antibodies)-eNOS (show NOS3 Antibodies) signaling pathway.
3'-UTR (show UTS2R Antibodies) SNP assoicated with milk composition traits and somatic cell score
Oxidized low-density lipoprotein receptor (show LDLR Antibodies) (OLR1) single nucleotide polymorphism haplotype is associated with milk fat yield and fat percentage
synergistic effects of cyclic tensile stretch load and ox-LDL on cell viability and proteoglycan (show Vcan Antibodies) synthesis in chondrocytes, which may be mediated through enhanced expression of LOX-1
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
oxidised low density lipoprotein (lectin-like) receptor 1
, oxidized low density lipoprotein (lectin-like) receptor 1
, lectin-like oxLDL receptor 1
, lectin-like oxidized LDL receptor 1
, lectin-type oxidized LDL receptor 1
, ox-LDL receptor 1
, oxidized low-density lipoprotein receptor 1
, C-type lectin domain family 8 member A
, ox LDL receptor 1
, oxidized low-density lipoprotein receptor 1, soluble form
, scavenger receptor class E, member 1
, Lectin-like oxidized low-density lipoprotein receptor-1
, lectin-like oxidized low-density lipoprotein receptor
, lectin-like oxidized LDL receptor-1
, oxidized low density lipoprotein receptor 1