anti-Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) Antibodies

OLR1 encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. Additionally we are shipping OLR1 Kits (90) and OLR1 Proteins (29) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
OLR1 4973 P78380
OLR1 108078 Q9EQ09
OLR1 140914 O70156
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Top anti-OLR1 Antibodies at antibodies-online.com

Showing 10 out of 228 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat aorta labeled with Anti-LOX-1 Polyclonal Antibody, Unconjugated (ABIN676988) followed by conjugation to the secondary antibody and DAB staining Human A549 cells probed with Rabbit Anti-LOX1 Polyclonal Antibody, Unconjugated . 100 μL Log in to see 3 to 7 Days
$318.45
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of LOX-1 expression in Jurkat cell lysate . 100 μg Log in to see 2 to 3 Days
$310.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of LOX-1/OLR1 using anti-LOX-1/OLR1 antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: human placenta tissue lysate.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-LOX-1/OLR1 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for LOX-1/OLR1 at approximately 38KD. The expected band size for LOX-1/OLR1 is at 31KD. 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-OLR1 Antibody Titration:  2.5ug/ml  Positive Control:  Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated IHC (p), ELISA, WB Immunohistochemical staining of rat brain tissue using LOX-1 antibody (dilution of primary antibody - 1:100) Western blot analysis of rat lung tissue using LOX-1 antibody (dilution at: 2 ug/ml) 100 μg Log in to see 10 to 15 Days
$531.13
Details
Human Mouse Un-conjugated BR, CyTOF, FACS, WB Detection of LOX-1/OLR1 in THP-1 Human Cell Line by Flow Cytometry. THP-1 human acute monocytic leukemia cell line were treated for 72 hours with 50 ng/mL PMA then stained with Mouse Anti-Human LOX-1/OLR1 Monoclonal Antibody. 100 μg Log in to see 8 to 9 Days
$299.00
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged OLR1 is approximately 3ng/ml as a capture antibody. 100 μg Log in to see 8 to 11 Days
$461.00
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using OLR1 antibody (ABIN5970808) at 1/1000 dilution. Immunohistochemistry of paraffin-embedded human gastric cancer using OLR1 Antibody (ABIN5970808) at dilution of 1/200 (40x lens). 100 μL Log in to see 11 to 16 Days
$426.40
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
$429.62
Details
Mouse Rabbit Un-conjugated ICC, IHC, WB Western Blot; Sample: Mouse Liver lysate; Primary Ab: 3µg/ml Rabbit Anti-Mouse LOX1 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Log in to see 13 to 16 Days
$212.00
Details

Top referenced anti-OLR1 Antibodies

  1. Human Polyclonal OLR1 Primary Antibody for IF (p), IHC (p) - ABIN676988 : Wu, Tang, Jiang, Li, Jiang, Liu: PCSK9 siRNA inhibits HUVEC apoptosis induced by ox-LDL via Bcl/Bax-caspase9-caspase3 pathway. in Molecular and cellular biochemistry 2011 (PubMed)
    Show all 6 Pubmed References

  2. Human Monoclonal OLR1 Primary Antibody for BR, CyTOF - ABIN5012947 : Vilser, Hueller, Nowicki, Hmeidan, Blumenauer, Spanel-Borowski et al.: The variable expression of lectin-like oxidized low-density lipoprotein receptor (LOX-1) and signs of autophagy and apoptosis in freshly harvested human granulosa cells depend on gonadotropin dose, ... in Fertility and sterility 2010 (PubMed)
    Show all 6 Pubmed References

  3. Human Polyclonal OLR1 Primary Antibody for IHC (fro), FACS - ABIN2475355 : Sawamura, Kume, Aoyama, Moriwaki, Hoshikawa, Aiba, Tanaka, Miwa, Katsura, Kita, Masaki: An endothelial receptor for oxidized low-density lipoprotein. in Nature 1997 (PubMed)
    Show all 4 Pubmed References

  4. Mouse (Murine) Monoclonal OLR1 Primary Antibody for FACS - ABIN4897693 : Biedroń, Konopiński, Marcinkiewicz, Józefowski: Oxidation by neutrophils-derived HOCl increases immunogenicity of proteins by converting them into ligands of several endocytic receptors involved in antigen uptake by dendritic cells and macrophages. in PLoS ONE 2015 (PubMed)
    Show all 3 Pubmed References

  5. Human Polyclonal OLR1 Primary Antibody for IF, ELISA - ABIN2475353 : Chen, Masaki, Sawamura: LOX-1, the receptor for oxidized low-density lipoprotein identified from endothelial cells: implications in endothelial dysfunction and atherosclerosis. in Pharmacology & therapeutics 2002 (PubMed)
    Show all 3 Pubmed References

  6. Human Polyclonal OLR1 Primary Antibody for IF, ELISA - ABIN2475354 : Li, Liu, Chen, Sawamura, Mehta: LOX-1, an oxidized LDL endothelial receptor, induces CD40/CD40L signaling in human coronary artery endothelial cells. in Arteriosclerosis, thrombosis, and vascular biology 2003 (PubMed)
    Show all 3 Pubmed References

  7. Human Polyclonal OLR1 Primary Antibody for ELISA - ABIN1997147 : Hinagata, Kakutani, Fujii, Naruko, Inoue, Fujita, Mehta, Ueda, Sawamura: Oxidized LDL receptor LOX-1 is involved in neointimal hyperplasia after balloon arterial injury in a rat model. in Cardiovascular research 2005 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal OLR1 Primary Antibody for FACS - ABIN4897702 : Lara-Guzmán, Gil-Izquierdo, Medina, Osorio, Álvarez-Quintero, Zuluaga, Oger, Galano, Durand, Muñoz-Durango: Oxidized LDL triggers changes in oxidative stress and inflammatory biomarkers in human macrophages. in Redox biology 2017 (PubMed)

  9. Human Polyclonal OLR1 Primary Antibody for ICC, IF - ABIN4331395 : Chen, Qiu, Lin, Nam, Ogbu-Nwobodo, Archibald, Joslin, Wun, Sawamura, Green: Lectin-like oxidized low-density lipoprotein receptor (LOX-1) in sickle cell disease vasculopathy. in Blood cells, molecules & diseases 2016 (PubMed)

  10. Human Polyclonal OLR1 Primary Antibody for ELISA, WB - ABIN4331396 : Shi, Cosentino, Camici, Akhmedov, Vanhoutte, Tanner, Lüscher: Oxidized low-density lipoprotein activates p66Shc via lectin-like oxidized low-density lipoprotein receptor-1, protein kinase C-beta, and c-Jun N-terminal kinase kinase in human endothelial cells. in Arteriosclerosis, thrombosis, and vascular biology 2011 (PubMed)

More Antibodies against OLR1 Interaction Partners

Rabbit Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) interaction partners

  1. ox-LDL and LOX-1 increase due to subarachnoid hemorrhage and they may play a role in the pathogenesis of vasospasm.

  2. LOX (show LOX Antibodies) and LOXL2 (show LOXL2 Antibodies) play an important role in wound healing after glaucoma filtration surgery. Targeting LOXL2 (show LOXL2 Antibodies) with an inhibitory monoclonal antibody (GS-607601) had a broader efficacy than targeting LOX (show LOX Antibodies), reducing angiogenesis and inflammation, and fibrosis.

  3. Angiotensin (1-7) inhibited LOX-1 expression and diminished Ang II (show AGT Antibodies)-mediated inflammation in endothelial cells

  4. Elevated LOX-1 expression and inflammatory responses are induced in hypercholesterolemic rabbits by Chlamydia pneumoniae GroEL1 heat shock protein.

  5. Early treatment with fluvastatin had a crucial endothelial protective effect by down-regulating LOX-1 expression level in atherosclerotic arteries in early atherosclerosis.

  6. LOX-1 expression appears to be closely associated with tissue factor (show F3 Antibodies) expression, apoptotic events and morphological vulnerability in atherosclerotic lesions

Human Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) interaction partners

  1. High LOX-1 ligand activity as a risk factor for ischemic stroke.

  2. The analysis also revealed that OLR1 is not required for the transcriptional regulation induced by oxidized PAPC (show PCDH8 Antibodies) but interestingly, OLR1 knockdown affected expression of CNN2 (show CNN2 Antibodies), HMRR, ITGB6 and KIF20A (show KIF20A Antibodies), all genes governing cell proliferation and motility.

  3. Data show that oxidized low density lipoprotein receptor 1 (LOX-1) is overexpressed in prostate cancer cells.

  4. L5-LDL, a naturally occurring mild oxidized LDL, induced G-CSF (show CSF3 Antibodies) and GM-CSF (show CSF2 Antibodies) production in human macrophages through LOX-1, ERK2 (show MAPK1 Antibodies), and NF-kappaB (show NFKB1 Antibodies) dependent pathways

  5. high LOX-1 expression in pancreatic cancer tissues is indicative for the occurrence of lymph node metastases, high TNM (show ODZ1 Antibodies) stages and a poor prognosis.

  6. lincRNAp21 is a major mediator of oxLDLinduced apoptosis and expression of LOX1 in human vascular endothelial cells, and acts via activation of PKCdelta (show PKCd Antibodies).

  7. this study shows that LOX-1 is involved in IL-1beta (show IL1B Antibodies) production and extracellular matrix breakdown in dental peri (show PLIN1 Antibodies)-implantitis

  8. Results showed that the scFv with N-terminal fusing peptides proteins demonstrated increased LOX-1-binding activity without decrease in stability. These findings will help increase the application efficacy of LOX-1 targeting scFv in LOX-1-based therapy

  9. The serum sLOX-1 level was higher in patients with large artery atherosclerotic stroke, and it was an independent predictor of functional outcome in patients with large artery atherosclerotic ischemic stroke.

  10. LOX-1 has a role in atherogenesis and tumorigenesis as a potential link in these diseases [review]

Mouse (Murine) Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) interaction partners

  1. The analysis also revealed that OLR1 is not required for the transcriptional regulation induced by oxidized PAPC (show PCDH8 Antibodies) but interestingly, OLR1 knockdown affected expression of CNN2 (show CNN2 Antibodies), HMRR, ITGB6 and KIF20A (show KIF20A Antibodies), all genes governing cell proliferation and motility.

  2. Reduced expression of miR (show MLXIP Antibodies)-98 may relate to LOX-1 expression and foam cell formation and lipid accumulation in aortas of ApoE (show APOE Antibodies)(-/-) mice.

  3. hyperoside inhibits oxLDL-induced LOX-1 expression, ERK (show EPHB2 Antibodies) activation, and cell proliferation through the oxLDL-LOX-1-ERK (show EPHB2 Antibodies) pathway in VSMCs.

  4. data revealed that miR (show MLXIP Antibodies)-let-7g exhibits anti-atherosclerotic activity, at least partially by targeting the LOX-1 signaling pathway.

  5. At low oxLDL levels LOX-1 activates the protective Oct-1/SIRT1 pathway, while at higher levels of the lipoprotein switches to the thrombogenic ERK1/2 pathway.

  6. Adiponectin, TNF-alpha (show TNF Antibodies), and LOX-1 exert complex regulatory effects on the coronary microvascular endothelial function in atherosclerotic ApoE (show APOE Antibodies) knockout mice.

  7. LOX-1 in cardiomyocytes plays an important role in the pathology of doxorubicin-induced cardiomyopathy. LOX-1 deletion altered the LOX-1-related signaling pathway, which led to improvements in cardiac function, myocardial inflammation, fibrosis and degenerative changes after DOX treatment.

  8. Therefore we concluded that HNG (show NRGN Antibodies) could inhibit ox-LDL-induced macrophage-derived foam cell formation, which occurs because of a decrease in lipid uptake and an increase in cholesterol efflux from macrophage cells.

  9. The study indicated that the LOX-1/ox-LDL system in chondrocytes plays a role in the pathogenesis of age-related knee knee osteoarthritis, which is potentially a target for preventing knee osteoarthritis progression.

  10. We demonstrated that varenicline upregulates expression of LOX-1 and CD36 (show CD36 Antibodies) significantly through alpha7 nAChR (show CHRNA7 Antibodies), thereby promoting oxLDL uptake in macrophages.

Cow (Bovine) Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1) interaction partners

  1. Endothelial LOX-1 overexpression in an atherosclerosis-prone LDL receptor (show LDLR Antibodies) knockout mice impairs endothelial function, proving its importance in the development of atherosclerosis.

  2. bta-miR (show MYLIP Antibodies)-370 has a negative regulatory effect on the OLR1 gene at both the gene and protein expression levels and has a role in lipid metabolism in bovine adipocytes

  3. Overexpression of LOX-1 leads to the attenuation of protective autophagy response in aortic endothelial cells.

  4. These results imply that the 3' UTR (show UTS2R Antibodies) SNP of the OLR1 gene is a strong candidate marker for selection in cattle breeding programs.

  5. Our data indicate that blocking the LOX-1 receptor signal pathway might be a promising way to improve steroid hormone concentrations in metabolically highly active female mammals

  6. In the present study, we show that inhibition of LOX-1 leads to a rearrangement of ceramide from the basal membrane toward the Golgi apparatus

  7. The downregulation of eNOS (show NOS3 Antibodies) by ox-low-density lipoprotein, as driven by LOX-1-mediated endoplasmic stress, is associated with the PI3K-Akt (show AKT1 Antibodies)-eNOS (show NOS3 Antibodies) signaling pathway.

  8. 3'-UTR (show UTS2R Antibodies) SNP assoicated with milk composition traits and somatic cell score

  9. Oxidized low-density lipoprotein receptor (show LDLR Antibodies) (OLR1) single nucleotide polymorphism haplotype is associated with milk fat yield and fat percentage

  10. synergistic effects of cyclic tensile stretch load and ox-LDL on cell viability and proteoglycan (show Vcan Antibodies) synthesis in chondrocytes, which may be mediated through enhanced expression of LOX-1

OLR1 Antigen Profile

Protein Summary

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with OLR1

  • oxidized low density lipoprotein receptor 1 (OLR1) antibody
  • oxidized low density lipoprotein (lectin-like) receptor 1 (Olr1) antibody
  • oxidized low density lipoprotein receptor 1 (Olr1) antibody
  • CLEC8A antibody
  • LOX-1 antibody
  • LOX1 antibody
  • LOXIN antibody
  • Oldlr1 antibody
  • Oldr1 antibody
  • Olr1 antibody
  • PLOX-1 antibody
  • Scare1 antibody
  • SLOX1 antibody
  • SR-EI antibody

Protein level used designations for OLR1

oxidised low density lipoprotein (lectin-like) receptor 1 , oxidized low density lipoprotein (lectin-like) receptor 1 , lectin-like oxLDL receptor 1 , lectin-like oxidized LDL receptor 1 , lectin-type oxidized LDL receptor 1 , ox-LDL receptor 1 , oxidized low-density lipoprotein receptor 1 , C-type lectin domain family 8 member A , hLOX-1 , ox LDL receptor 1 , oxidized low-density lipoprotein receptor 1, soluble form , scavenger receptor class E, member 1 , Lectin-like oxidized low-density lipoprotein receptor-1 , lectin-like oxidized low-density lipoprotein receptor , BLOX1 , LOX-1 , bLOX-1 , lectin-like oxidized LDL receptor-1 , oxidized low density lipoprotein receptor 1

GENE ID SPECIES
473362 Pan troglodytes
486694 Canis lupus familiaris
100009322 Oryctolagus cuniculus
4973 Homo sapiens
108078 Mus musculus
140914 Rattus norvegicus
281368 Bos taurus
396724 Sus scrofa
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