OLR1 antibody (APC)

Catalog No. ABIN7505993

Product Details anti-OLR1 Antibody (APC)

Target: OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This OLR1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Purpose: Anti-Hu LOX1 APC

Specificity: The mouse monoclonal antibody 15C4 recognizes an extracellular epitope of LOX1, a C-type lectin transmembrane protein.

Purification: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: fusion protein of human LOX1 ectodomain and of human IgG Fc

Clone: 15C4

Isotype: IgG2a kappa

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for OLR1

Target: OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))

Alternative Name: LOX1 (OLR1 Products)

Synonyms: OLR1 antibody, LOX1 antibody, Olr1 antibody, CLEC8A antibody, LOXIN antibody, SCARE1 antibody, SLOX1 antibody, LOX-1 antibody, SR-EI antibody, Scare1 antibody, Oldlr1 antibody, Oldr1 antibody, PLOX-1 antibody, oxidized low density lipoprotein receptor 1 antibody, oxidized low density lipoprotein (lectin-like) receptor 1 antibody, OLR1 antibody, Olr1 antibody

Background: Oxidized low density lipoprotein receptor 1,LOX1, a 31 kDa type II transmembrane protein, is a C-type lectin, functioning as a scavenger receptor for e.g. oxidized low density lipoprotein, apoptotic heat shock proteins, or CRP. It is expressed by macrophages, fibroblasts, platelets, endothelial cells, and smooth muscle cells, and its defects can lead to atherosclerosis. Its expression is enhanced under inflammatory conditions. Multiple splicing variants have been identified.,OLR1, SLOX1, SCARE1, CLEC8A

Gene ID: 4973

UniProt: P78380