anti-PROP Paired-Like Homeobox 1 (PROP1) Antibodies

PROP1 encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Additionally we are shipping PROP1 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PROP1 19127 P97458
PROP1 5626 O75360
PROP1 266738  
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Top anti-PROP1 Antibodies at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PROP1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  COLO205 cell lysate PROP1 is supported by BioGPS gene expression data to be expressed in COLO205 WB Suggested Anti-PROP1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: COLO205 cell lysate  PROP1 is supported by BioGPS gene expression data to be expressed in COLO205 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 6 to 7 Days
$291.53
Details
Dog Rabbit Un-conjugated WB 100 μL Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of PROP1 expression in A431 whole cell lysate ,The lane on the left is treated with the antigen-specific peptide. 100 μL Log in to see 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated IP, WB Immunoprecipitation of PROP1 transfected lysate using anti-PROP1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with PROP1 purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of PROP1 expression in transfected 293T cell line by PROP1 MaxPab polyclonal antibody.Lane 1: PROP1 transfected lysate(25 KDa).Lane 2: Non-transfected lysate. 100 μL Log in to see 11 to 12 Days
$425.71
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 11 to 14 Days
$507.83
Details
Human Goat Biotin ELISA   100 μL Log in to see 16 Days
$653.71
Details
Human Goat PE ELISA   100 μL Log in to see 16 Days
$653.71
Details
Human Goat FITC ELISA   100 μL Log in to see 16 Days
$653.71
Details
Human Goat Alkaline Phosphatase (AP) ELISA   100 μL Log in to see 16 Days
$653.71
Details

Top referenced anti-PROP1 Antibodies

  1. Human Polyclonal PROP1 Primary Antibody for ELISA - ABIN4240033 : Kelberman, Turton, Woods, Mehta, Al-Khawari, Greening, Swift, Otonkoski, Rhodes, Dattani: Molecular analysis of novel PROP1 mutations associated with combined pituitary hormone deficiency (CPHD). in Clinical endocrinology 2009 (PubMed)

More Antibodies against PROP1 Interaction Partners

Mouse (Murine) PROP Paired-Like Homeobox 1 (PROP1) interaction partners

  1. Genomic profiling reveals that PROP1 binds to genes expressed in epithelial cells like Claudin 23, and to epithelial-mesenchymal transition inducer genes like Zeb2, Notch2 and Gli2. Zeb2 activation appears to be a key step in the epithelial-mesenchymal transition process.

  2. SOX2 is a regulatory factor of Prop1 expression

  3. Data show that human paired like homeodomain factor 1 (PROP1) can substitute functionally for mouse Prop1.

  4. endocochlear potential and KCNJ10 immunostaining in the stria vascularis are indistinguishable from wild type, and no differences in neurofilament or synaptophysin staining are evident in Prop1(df) mutants

  5. Data report the spatial and temporal regulation of Otx2 in normal mice and Prop1 mutant.

  6. Several components of the main GH-signaling pathways exhibit enhanced sensitivity to the hormone in liver and muscle of Ames dwarf mice.

  7. Studies suggest that TLE1 and TLE3 might also play roles independent of HESX1 by interacting with other transcription factors like PROP1.

  8. Lhx4 and Prop1 have critical, but mechanistically different roles in specification and expansion of specialized anterior pituitary cells

  9. Tcf4 and Aes influence pituitary growth and development, and place Tcf4 and Tle3 in the genetic hierarchy with Prop1

  10. PROP1 has a role in pituitary gland growth

  11. variation in PROP1 expression could affect the growth spurt and the onset of puberty in humans.

  12. Prop-1 modulates the synthesis of FSH at the transcriptional level.

  13. Functional transcriptional control sequences in the Prop1 gene for spatial expression during pituitary development.

  14. These data reveal important overlapping functions of Hes1 and Prop1 in cell differentiation and movement that are critical for pituitary organogenesis.

Human PROP Paired-Like Homeobox 1 (PROP1) interaction partners

  1. PROP1 mutations are a prevalent cause of congenital CPHD with OPP, and therefore, PROP1 sequencing must be the first step of molecular investigation in patients with CPHD and OPP, especially in populations with a high frequency of PROP1 mutations.

  2. Deletion in the PROP1 gene is associated with Combined pituitary hormone deficiency.

  3. The anterior pituitary gland comprised specialized cell-types that arise from stem cells expressing SOX2 and PROP1, which is necessary to establish the stem cell pool and promote an epithelial to mesenchymal-like transition, releasing progenitors from the niche. [review]

  4. GH replacement successfully corrects the growth deficit in children with Growth Hormone Deficiency . While the genetic aetiology remains undefined in most cases of Isolated Growth Hormone Deficiency , PROP1 mutations constitute a major cause for Multiple Pituitary Hormone Deficiencies. Persistence of Growth Hormone Deficiency into adulthood is related to abnormal pituitary morphology.

  5. The present study reports on screening of POU1F1, PROP1, and HESX1 in combined pituitary hormone deficiency patients and the novel variations identified.

  6. A compound heterozygosity in the PROP1 gene has been identified for both probands. The first change represents a mutational hot spot (c.150delA, p.R53fsX164), whereas the second is a novel alteration (p.R112X) that leads to protein disruption. The resulting clinical phenotype was surprisingly distinct compared to most patients with genetic alterations in PROP1.

  7. the most frequent variants in the PROP1 gene are not a consequence of variant hot spots as previously assumed, but are founder variants.

  8. Data show that human paired like homeodomain factor 1 (PROP1) can substitute functionally for mouse Prop1.

  9. A novel heterozygous mutation in the HESX1 gene and a novel homozygous mutation in the PROP1 gene were detected in 2 pedigrees with combined pituitary hormone deficiency

  10. The c.301_302delAG homozygous genotype had a high frequency of 38%, reaching 100% in group with familial cases of multiple pituitary hormone deficiency and 16% in group with sporadic forms of MPHD.

  11. investigated the specific mutations in PROP1, POU1F1, LHX3, and HESX1 genes in patients with combined pituitary hormone deficiency (CPHD) in Turkey

  12. The p.R73C PROP1 mutation was the most frequent mutation in Congenital hypopituitarism in a Moroccan cohort.

  13. The various levels of specific miRNAs, particularly miR-593 and miR-511 whose direct target is the PROP1 gene, may serve as a non-invasive diagnostic biomarkers for children with CPHD.

  14. mutations in the PROP-1 gene in cases with CPHD were expected to be more prevalent in our population due to consanguinity, but it was found that these mutations were far less than expected and that it was rare in non-familial cases.

  15. High prevalence of PROP1 defects in Lithuania is due to 296delGA mutation, suggesting a founder effect.

  16. A homozygous frameshift mutation of PROP1 (296delGA) was identified in siblings. Defects in PROP1 cause progressive deficiency of multiple pituitary hormones; PROP1 deficiency may present as isolated central hypothyroidism at a very young age

  17. AES binds to PROP1 and represses its expression; PROP1 mutation is a likely cause of combined pituitary hormone deficiency.

  18. Case Report: unfavourable long-term course of an untreated patient with PROP-1 gene mutation-associated combined pituitary horme deficiency.

  19. Peculiar prolactinomas in patients with pituitary developmental PROP1 gene mutations

  20. Variations with a functional significance conferring susceptibility to combined growth hormone deficiency have been identified in the PROP1 gene

Pig (Porcine) PROP Paired-Like Homeobox 1 (PROP1) interaction partners

  1. Data suggest that formation of a heterodimer between HESX1 and PROP1 allows HESX1 to become active, and that PROP1 then replaces HESX1 to advance to the middle stage of pituitary development.

  2. Prop-1 participates in the regulation of FSHbeta gene

  3. Prop-1 might be involved in development of gonadotropes and hormone production

  4. Dimeric binding of PROP1 is able to recognize diverse palindromic TAAT sequences separated by 3 nucleotides and to exhibit its transcriptional activity.

Cow (Bovine) PROP Paired-Like Homeobox 1 (PROP1) interaction partners

  1. The H173R mutation in PROP1 can be considered as a DNA marker for selecting individuals with superior growth traits, thereby contributing to research on breeding and genetics in the beef industry.

  2. missense mutation affects male fertility and milk production traits in Holsteins

PROP1 Antigen Profile

Protein Summary

This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occurs prior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitary development and hormone expression. Mutations in this gene have been associated with combined pituitary hormone deficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin, and thyroid-stimulating hormone.

Gene names and symbols associated with PROP1

  • paired like homeodomain factor 1 (Prop1) antibody
  • PROP paired-like homeobox 1 (PROP1) antibody
  • PROP paired-like homeobox 1 (Prop1) antibody
  • CPHD2 antibody
  • df antibody
  • PROP-1 antibody

Protein level used designations for PROP1

Ames dwarf , homeobox protein prophet of Pit-1 , pituitary specific homeodomain factor , pituitary-specific homeodomain factor , prophet of Pit-1 , PROP paired-like homeobox 1 , prophet of Pit1, paired-like homeodomain transcription factor , PROP-1 , paired like homeodomain factor 1 , prophet of Pit1 paired-like homeodomain transcription factor

GENE ID SPECIES
19127 Mus musculus
374220 Gallus gallus
5626 Homo sapiens
474647 Canis lupus familiaris
397280 Sus scrofa
282563 Bos taurus
266738 Rattus norvegicus
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