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anti-Paired-Like Homeobox 2a (PHOX2A) Antibodies

The protein encoded by PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. Additionally we are shipping Paired-Like Homeobox 2a Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PHOX2A 401 O14813
PHOX2A 11859 Q62066
PHOX2A 116648 Q62782
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Top anti-Paired-Like Homeobox 2a Antibodies at antibodies-online.com

Showing 10 out of 61 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PHOX2A Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: Human Stomach 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemistry with Testis tissue at an antibody concentration of 5µg/ml using anti-PHOX2A antibody (ARP31726_P050) WB Suggested Anti-PHOX2A Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: 721_B cell lysate PHOX2A is supported by BioGPS gene expression data to be expressed in 721_B 100 μL 2 to 3 Days
$319.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-PHOX2A Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: MCF7 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg 6 to 7 Days
$429.84
Details
Cow Rabbit Un-conjugated IHC, IHC (p), WB Anti-PHOX2A antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody ABIN958315 concentration 5 ug/ml. 100 μL 11 to 14 Days
$727.83
Details
Cow Goat Un-conjugated ELISA, WB 100 μg 11 to 14 Days
$610.50
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Cow Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated IF, RNAi, ELISA, WB Immunofluorescence of monoclonal antibody to PHOX2A on HeLa cell. [antibody concentration 10 ug/ml] PHOX2A monoclonal antibody (M01), clone 4F6 Western Blot analysis of PHOX2A expression in PC-12 . 100 μg 11 to 12 Days
$364.00
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB   0.1 mg 4 to 8 Days
$522.50
Details

Top referenced anti-Paired-Like Homeobox 2a Antibodies

  1. Human Polyclonal PHOX2A Primary Antibody for ELISA, WB - ABIN4345384 : Fan, Huang, Kieran, Zhu: Effects of transcription factors Phox2 on expression of norepinephrine transporter and dopamine beta-hydroxylase in SK-N-BE(2)C cells. in Journal of neurochemistry 2009 (PubMed)

More Antibodies against Paired-Like Homeobox 2a Interaction Partners

Human Paired-Like Homeobox 2a (PHOX2A) interaction partners

  1. PHOX2A expression is finely controlled during retinoic acid differentiation and this, together with PHOX2B down-regulation.

  2. Genetic linkage was found at 11q13 between D11S4151 and D11S1320 and the PHOX2A gene.

  3. Patients with ARIX and/or PHOX2B polymorphisms had less hypoplastic superior oblique muscles.

  4. Mutations in the human ortholog of Aristaless cause X-linked mental retardation and epilepsy

  5. The paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation status

  6. PHOX2A mutation analysis revealed a novel nonsense mutation in CFEOM2 (congenital fibrosis of extraocular muscles type 2)

  7. the polymorphisms of the ARIX gene and PHOX2B gene may be genetic risk factors for the development of congenital superior oblique muscle palsy

  8. PHOX2A, but not PHOX2B, seems to act directly on the c-RET promoter

  9. Together, these results suggest that phosphorylation of Arix by ERK1/2 inhibits its ability to interact with target genes, and that both specificity of expression and modulation by external stimuli are monitored through the same transcription factor.

  10. These results demonstrate the direct interactions of the Phox2a and b and dHAND transcription factors within a noradrenergic cell type

  11. the alpha3 subunit is expressed in every terminally differentiated ganglionic cell, this is the first example of a "pan-autonomic" gene whose expression is regulated by PHOX2 proteins.

  12. PHOX2A, like PHOX2B, is involved in the cascade leading to transcription factor TLX2 transactivation and presumably is involved in intestinal neuronal differentiation.

  13. a variant of Secretogranin II has a role in regulation by PHOX2 transcription factors and in hypertension

  14. The ARIX 153G>A polymorphism might be a genetic risk factor for the development of congenital superior oblique muscle palsy

  15. PHOX2A and PHOX2B genes are highly co-expressed in human neuroblastoma.

  16. PHOX2A gene, localized in a tumor suppressor candidate region at 11q, weas screened for mutations by DNA sequencing in 47 tumors of different stages.

  17. Transfection of Phox2a cDNA significantly increases mRNA and protein levels of norepinephrine transporter and dopamine beta-hydroxylase.

  18. Our 16-patient sample suggests that KIF21A and PHOX2A sequence variation does not have a role in common forms of congenital incomitant vertical strabismus.

Mouse (Murine) Paired-Like Homeobox 2a (PHOX2A) interaction partners

  1. All E1 sequences from lamprey to mouse responded equally well to Phox2a and the Isl1-Lhx3 complex. Conversely, E2, the enhancer for limb-innervating motor neurons, was only found in tetrapod animals

  2. reveal an unanticipated role for Lmx1b in regulating Phox2a expression and the sequential specification of ocular motor neurons (OMNs) and red nucleus neurons (RNNs) from progenitors located lateral to dopamine neurons in the midbrain

  3. Maintenance of noradrenergic differentiation during embryogenesis requires ongoing expression of Phox2b in sympathetic ganglia, and of Phox2a in the main noradrenergic center, the locus coeruleus.

  4. Noradrenaline, A6 neurons, and the Phox2a gene, which is crucial for the generation of A6 neurons, are essential for development of normal respiratory rhythm in neonatal mice

  5. Phox2 genes have roles in neural differentiation

  6. These data indicate that Phox2a plays a critical role in the ontogeny of the reflex control of inspiration.

Paired-Like Homeobox 2a (PHOX2A) Antigen Profile

Protein Summary

The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles.

Gene names and symbols associated with PHOX2A

  • paired like homeobox 2a (PHOX2A) antibody
  • paired-like homeobox 2a (Phox2a) antibody
  • paired-like homeobox 2a (phox2a) antibody
  • paired like homeobox 2a S homeolog (phox2a.S) antibody
  • paired-like homeobox 2a (PHOX2A) antibody
  • arix antibody
  • CFEOM2 antibody
  • FEOM2 antibody
  • NCAM2 antibody
  • phox2 antibody
  • Pmx2 antibody
  • Pmx2a antibody
  • sou antibody
  • xphox2a antibody
  • zgc:77364 antibody

Protein level used designations for PHOX2A

ARIX1 homeodomain protein , aristaless homeobox homolog , aristaless homeobox protein homolog , arix homeodomain protein , paired mesoderm homeobox protein 2A , PHOX2A homeodomain protein , aristaless homeobox gene homolog , paired mesoderm homeobox 2a , aristaless homeobox , soulless , paired-like (aristaless) homeobox 2a

GENE ID SPECIES
401 Homo sapiens
11859 Mus musculus
116648 Rattus norvegicus
404602 Danio rerio
402788 Xenopus laevis
395595 Gallus gallus
485208 Canis lupus familiaris
507670 Bos taurus
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