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The protein encoded by PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. Additionally we are shipping Paired-Like Homeobox 2a Proteins (4) and many more products for this protein.
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Human Polyclonal PHOX2A Primary Antibody for ELISA, WB - ABIN4345384
Fan, Huang, Kieran, Zhu: Effects of transcription factors Phox2 on expression of norepinephrine transporter and dopamine beta-hydroxylase in SK-N-BE(2)C cells. in Journal of neurochemistry 2009
The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles.
ARIX1 homeodomain protein
, aristaless homeobox homolog
, aristaless homeobox protein homolog
, arix homeodomain protein
, paired mesoderm homeobox protein 2A
, PHOX2A homeodomain protein
, aristaless homeobox gene homolog
, paired mesoderm homeobox 2a
, aristaless homeobox
, paired-like (aristaless) homeobox 2a