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anti-Phosphomevalonate Kinase (PMVK) Antibodies

PMVK encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Additionally we are shipping Phosphomevalonate Kinase Proteins (14) and Phosphomevalonate Kinase Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PMVK 10654 Q15126
PMVK 68603 Q9D1G2
PMVK 310645  
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Top anti-Phosphomevalonate Kinase Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated IHC (p), ELISA Human PMVK / phosphomevalonate kinase Immunohistochemistry(IHC) 7832 Human PMVK / phosphomevalonate kinase Immunohistochemistry(IHC) 7833 100 μL 14 to 16 Days
$247.82
Details
Human Mouse Un-conjugated IF, WB 100 μL 11 to 14 Days
$522.50
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC202867 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PMVK antibody (ABIN2454969), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PMVK (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PMVK. 0.1 mL 2 to 3 Days
$462.00
Details
Human Mouse Un-conjugated WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PMVK (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PMVK. 0.1 mL 2 to 3 Days
$482.90
Details
Rat Rabbit Un-conjugated IHC (p), WB Anti-PMVK antibody, Western blotting WB: Rat Cardiac Muscle Tissue Lysate Anti-PMVK antibody, IHC(P) IHC(P): Rat Skeletal Muscle Tissue 100 μg 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Immunohistochemical analysis of paraffin embedded rat skeletal muscle sections, staining PMVK in cytoplasm, DAB chromeric reaction Western blot analysis of cardiac muscle tissue lysis using PMKV antibody 0.1 mg 6 to 8 Days
$456.50
Details
Human Mouse Un-conjugated IP, ELISA, WB Western Blot analysis of PMVK expression in transfected 293T cell line by PMVK monoclonal antibody (M07), clone 2B8.Lane 1: PMVK transfected lysate(22 KDa).Lane 2: Non-transfected lysate. Immunoprecipitation of PMVK transfected lysate using anti-PMVK monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with PMVK MaxPab rabbit polyclonal antibody. 100 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human kidney labeled with Rabbit Anti-PMVK Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3 to 7 Days
$317.90
Details
Human Rabbit Un-conjugated IP, WB Immunoprecipitation of PMVK transfected lysate using anti-PMVK MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with PMVK purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of PMVK expression in transfected 293T cell line by PMVK MaxPab polyclonal antibody.Lane 1: PMVK transfected lysate(22.00 KDa).Lane 2: Non-transfected lysate. 100 μL 11 to 12 Days
$425.71
Details
Human Mouse Un-conjugated WB Western Blot analysis of PMVK expression in transfected 293T cell line by PMVK MaxPab polyclonal antibody.Lane 1: PMVK transfected lysate(21.12 KDa).Lane 2: Non-transfected lysate. PMVK MaxPab polyclonal antibody. Western Blot analysis of PMVK expression in human kidney. 50 μL 11 to 12 Days
$440.00
Details

More Antibodies against Phosphomevalonate Kinase Interaction Partners

Human Phosphomevalonate Kinase (PMVK) interaction partners

  1. Data indicate that exome sequencing revealed disseminated superficial porokeratosis (DSP)-associated mutations in phosphomevalonate kinase gene (PMVK).

  2. found an exclusive cytosolic localization of both endogenously expressed PMVK(in human fibroblasts, human liver, and HEK293 cells) and overexpressed PMVK. No indication of a peroxisomal localization was obtained.

  3. Functional evaluation of conserved basic residues in PMVK is reported.

  4. This is the first report of hPMK crystal structure that suggests a potential substrate binding site and a possible enzyme catalytic mechanism.

  5. Binding of mevalonate 5-phosphate causes the phosphomevalonate kinase structure to compress (tau(c) = 13.5 nsec), whereas subsequent binding of Mg-ADP opens the structure up (tau(c) = 15.6 nsec).

Phosphomevalonate Kinase (PMVK) Antigen Profile

Protein Summary

This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis.

Gene names and symbols associated with PMVK

  • phosphomevalonate kinase (PMVK) antibody
  • phosphomevalonate kinase (Mpk) antibody
  • GHMP kinase family protein (AT1G31910) antibody
  • phosphomevalonate kinase (CpipJ_CPIJ015413) antibody
  • phosphomevalonate kinase (Bm1_05275) antibody
  • phosphomevalonate kinase (pmvk) antibody
  • phosphomevalonate kinase (LOAG_11811) antibody
  • phosphomevalonate kinase (Tsp_06629) antibody
  • phosphomevalonate kinase (LOC100282968) antibody
  • phosphomevalonate kinase (Pmvk) antibody
  • 1110011E12Rik antibody
  • 2900002L22Rik antibody
  • AV001327 antibody
  • F5M6.9 antibody
  • F5M6_9 antibody
  • HUMPMKI antibody
  • MPK_Bm antibody
  • PMK antibody
  • PMKA antibody
  • PMKASE antibody
  • zgc:162701 antibody

Protein level used designations for PMVK

phosphomevalonate kinase , hPMK , PMKase

GENE ID SPECIES
457350 Pan troglodytes
612251 Canis lupus familiaris
692835 Bombyx mori
717014 Macaca mulatta
840081 Arabidopsis thaliana
6049213 Culex quinquefasciatus
6095986 Brugia malayi
8570979 Lactobacillus johnsonii FI9785
9949270 Loa loa
10909538 Trichinella spiralis
100003383 Danio rerio
100282968 Zea mays
10654 Homo sapiens
68603 Mus musculus
310645 Rattus norvegicus
100152301 Sus scrofa
513533 Bos taurus
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