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Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Additionally we are shipping and many more products for this protein.
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Human Polyclonal PSD4 Primary Antibody for IHC (p), ELISA - ABIN542761
Tanahashi, Murakami, Minami, Shimbara, Hendil, Tanaka: Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis. in The Journal of biological chemistry 2000
Show all 3 Pubmed References
results identify EFA6B as a novel antagonist in breast cancer and they point to its regulatory and signaling pathways as rational therapeutic targets in aggressive forms of this disease
One of the cytohesin family of guanine nucleotide exchange factors, Tic may act on the ARF family of GTP-binding proteins. A PH domain with similar sequence and relative position to those in other cytohesins may allow association with phosphoinositides.
Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5- bisphosphate and phosphatidylinositol 4,5-bisphosphate (By similarity).
ADP-ribosylation factor guanine nucleotide-exchange factor 6
, PH and SEC7 domain-containing protein 4
, SEC7 homolog
, exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B
, exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B
, exchange factor for ARF6 B
, pleckstrin homology and SEC7 domain-containing protein 4
, telomeric of interleukin-1 cluster protein