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Involved in inducing the expression of IFN-gamma- responsive genes (By similarity).. Additionally we are shipping and and many more products for this protein.
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PARP9 and PARP14 (show PARP14 Antibodies) regulate macrophage activation in macrophage cell lines treated with either IFNgamma or IL-4 (show IL4 Antibodies); PARP14 (show PARP14 Antibodies) silencing induces pro-inflammatory genes and STAT1 (show STAT1 Antibodies) phosphorylation in M(IFNgamma) cells, whereas it suppresses anti-inflammatory gene expression and STAT6 (show STAT6 Antibodies) phosphorylation in M(IL-4 (show IL4 Antibodies)) cells
Dtx3L heterodimerization with Parp9 enables NAD(+) and poly(ADP-ribose) regulation of E3 activity.
The present study further suggests that the combined targeted inhibition of STAT1 (show STAT1 Antibodies), ARTD8 (show PARP14 Antibodies), ARTD9 and/or DTX3L (show DTX3L Antibodies) could increase the efficacy of chemotherapy or radiation treatment in prostate and other high-risk tumor types with an increased STAT1 (show STAT1 Antibodies) signaling.
BAL1 represses the anti-proliferative and pro-apoptotic IFNgamma-STAT1 (show STAT1 Antibodies)-IRF1 (show IRF1 Antibodies)-p53 (show TP53 Antibodies) axis and mediates proliferation, survival and chemo-resistance in DLBCL.
Data establish that BAL1 and BBAP are bona fide members of a DNA damage response pathway and are directly associated with PARP1 activation, BRCA1 recruitment, and double-strand break repair.
BAL1 and BBAP (show DTX3L Antibodies) are located on chromosome 3q21 in a head-to-head orientation and are regulated by a IFN-gamma (show IFNG Antibodies)-responsive bidirectional promoter.
Determination of Poly (ADP-ribose) polymerase (PARP (show PARP1 Antibodies)) homologues in human ejaculated sperm and its correlation with sperm maturation.
this study shows that Parp9-deficient mice are viable, fertile, and do not show any overt phenotype; Parp9 is dispensable for B-cell development, and that Parp9 is not essential for double-stranded DNA break repair, or that strong compensatory mechanisms exist
Data indicate that PARP (show PARP1 Antibodies) polymerase PARP9-E3 ligase DTX3L (show DTX3L Antibodies) interacts with STAT1 (show STAT1 Antibodies) transcription factor and enhances translocation of STAT1 (show STAT1 Antibodies) to the nucleus.
Data show that Parp-9 is developmentally regulated, and prominently expressed in the thymus and specific regions of the brain and gut (show GUSB Antibodies).
Involved in inducing the expression of IFN-gamma- responsive genes (By similarity).
poly [ADP-ribose] polymerase 9
, poly (ADP-ribose) polymerase family, member 9
, ADP-ribosyltransferase diphtheria toxin-like 9
, b aggressive lymphoma protein
, poly (ADP-ribose) polymerase 9
, b aggressive lymphoma protein homolog