PARP9 antibody (N-Term)

Catalog No. ABIN2778121

This Rabbit Polyclonal antibody specifically detects PARP9 in WB. It exhibits reactivity toward Human.

Quick Overview for PARP9 antibody (N-Term) (ABIN2778121)

Target: PARP9 (Poly (ADP-Ribose) Polymerase Family, Member 9 (PARP9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARP9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PARP9 Antibody

Binding Specificity: N-Term

Purpose: PARP9 Antibody - N-terminal region

Sequence: LHGGGLALAL VKAGGFEIQE ESKQFVARYG KVSAGEIAVT GAGRLPCKQI

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against PARP9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PARP9

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33776-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PARP9

Target: PARP9 (Poly (ADP-Ribose) Polymerase Family, Member 9 (PARP9))

Alternative Name: PARP9

Background:

Background Information: PARP9 contains 2 Macro domains and 1 PARP catalytic domain. PARP9 is overexpressed at significantly higher levels in fatal high-risk diffuse large B-cell lymphomas (DLB-CL) compared to cured low-risk tumors. Overexpression of PARP9 in B-cell lymphoma transfectants may promote malignant B-cell migration. The function of PARP9 remains unknown.

Gene Name: Poly (ADP-ribose) polymerase family, member 9

Alternative Symbols: BAL, BAL1, ARTD9, MGC:7868

Protein Name: Poly [ADP-ribose] polymerase 9

Molecular Weight: 96kDa

Gene ID: 83666

NCBI Accession: NP_113646

UniProt: Q8IXQ6