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DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
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a mammalian interspersed repeat (MIR (show MLXIP Antibodies)) nested in antisense orientation within the first intron of the Polr3e gene, affects Polr3e expression through transcriptional interference
Results identify Sin as a novel regulator of medullary thymic epithelial cell development and t cell tolerance.
Data describe the purification and identification of RNA polymerase III subunits RPC2 (show POLR3B Antibodies) and RPC5.
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific periphjeric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Essential for efficient transcription from both the type 2 VAI and type 3 U6 RNA polymerase III promoters. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- Kappa-B through the RIG-I pathway (By similarity).
polymerase (RNA) III (DNA directed) polypeptide E (80kD)
, RNA polymerase III polypeptide E
, DNA-directed RNA polymerase III subunit RPC5
, RNA polymerase III subunit 5
, RNA polymerase III subunit C5
, sex-lethal interactor homolog
, DNA-directed RNA polymerase III 80 kDa polypeptide
, RNA polymerase III 80 kDa subunit RPC5