anti-Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) Antibodies

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. Additionally we are shipping PTGS1 Kits (71) and PTGS1 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTGS1 19224 P22437
PTGS1 24693 Q63921
PTGS1 5742 P23219
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Top anti-PTGS1 Antibodies at antibodies-online.com

Showing 10 out of 151 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-PTGS1 Antibody Titration: </b>5.0ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN184671 staining (1µg/ml) of HeLa lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Rabbit Un-conjugated WB Western blot analysis of PGHS-1 expression in HeLa (A), Raw264.7 (B), rat kidney (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ICC, IHC, WB Figure. Western Blot; Sample: Human A431 Cells. 100 μg Log in to see 13 to 16 Days
$316.00
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Heart (formalin-fixed, paraffin-embedded) stained with PTGS1 antibody ABIN461923 at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. Human Kidney (formalin-fixed, paraffin-embedded) stained with PTGS1 antibody ABIN461923 at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$484.00
Details
Human Goat Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$455.40
Details
Bat Rabbit Un-conjugated IHC (p), WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB AP23304PU-N COX1 antibody staining of Paraffin Embedded Rat Spleen Tissue Sections in cytoplasm. DAB chromogenic reaction. Western blot analysis of rat testicle tissue lysis using COX1 antibody 0.1 mg Log in to see 6 to 8 Days
$379.50
Details

PTGS1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-PTGS1 Antibodies

  1. Human Polyclonal PTGS1 Primary Antibody for IF (p), IHC (p) - ABIN670446 : Li, Wang, Jiang, Xu, Zhang, Liu, Zhai: Combined effects of cyclooxygenase-1 and cyclooxygenase-2 selective inhibitors on ovarian carcinoma in vivo. in International journal of molecular sciences 2011 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal PTGS1 Primary Antibody for IF, IHC (p) - ABIN1882120 : Helmersson, Arnlöv, Axelsson, Basu: A polymorphism in the cyclooxygenase 1 gene is associated with decreased inflammatory prostaglandin F2alpha formation and lower risk of cardiovascular disease. in Prostaglandins, leukotrienes, and essential fatty acids 2009 (PubMed)

More Antibodies against PTGS1 Interaction Partners

Horse (Equine) Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) interaction partners

  1. This study showed that COX-1 and COX-2 (show PTGS2 Antibodies) in genital carcinomas in the horse is poor; microsomal PGES (show PTGES Antibodies)-1 is more prominently expressed.

  2. COX-1 and COX-2 (show PTGS2 Antibodies) genes were constitutively expressed in baseline samples. Low-flow ischemia resulted in significant upregulation of COX-2 (show PTGS2 Antibodies) gene expression at each subsequent time point, compared with baseline values.

  3. In this study, both COX-1 and COX-2 (show PTGS2 Antibodies) were expressed in the colon before induced ischemia; ischemic injury increased expression of COX-2 (show PTGS2 Antibodies).

  4. Immunoreactivity for COX-1 and COX-2 (show PTGS2 Antibodies) is high in equine corneal SCC (show CYP11A1 Antibodies), possibly indicating that COX (show CPOX Antibodies) plays a role in oncogenesis or progression of this tumor type at this site.

Rabbit Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) interaction partners

  1. These results suggest that licochalcones inhibit collagen-induced platelet aggregation accompanied by inhibition of COX-1 (show COX1 Antibodies) activity.

Mouse (Murine) Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) interaction partners

  1. Data (including data from studies in knockout mice) suggest that delayed parturition in Cox-1 knockout mice is result of impaired luteolysis and cervical dilation, despite the presence of strong uterine contractions.

  2. Data suggest that Il4 (show IL4 Antibodies) (usually released from helper T-cells) induces Cox1 (show COX1 Antibodies) in macrophages at post-transcriptional level; activation of Ampk (show PRKAA1 Antibodies) (catalytic subunit Prkaa1 (show PRKAA1 Antibodies)) by metformin blocks Il4 (show IL4 Antibodies)-dependent induction of Cox1 (show COX1 Antibodies) and blocks macrophage polarization/activation. (Il4 (show IL4 Antibodies) = interleukin-4 (show IL4 Antibodies); Cox1 (show COX1 Antibodies) = cyclooxygenase 1; Ampk (show PRKAA1 Antibodies) = AMP-activated protein kinase (show PRKAA2 Antibodies))

  3. Specific inhibition of PGE2 synthesis by targeting mPGES-1 (show PTGES Antibodies) may weaken host defense against bacterial infections.

  4. Dimethyl ester of bilirubin exhibits anti-inflammatory activity through inhibition of secretory phospholipase A2 (show YWHAZ Antibodies), lipoxygenase and cyclooxygenase.

  5. role of cyclooxygenase-1 and -2 in endothelium-dependent contraction of atherosclerotic mouse abdominal aortas

  6. Suggest the expression of COX-1 and COX-2 (show COX2 Antibodies) in the urothelium protects bladder damage from radiation.

  7. COX-1 inhibitor SC-560 has a protective effect on the thromboxane A2-mediated decrease in renal function in response to endotoxin.

  8. Expression of COX-1 is essential for the protection of liver against chemical-induced hepatotoxicity and required for hepatic homeostatic maintenance.

  9. Data suggest that multitarget FAAH (show FAAH Antibodies)/Cox (show CPOX Antibodies) blockade may provide a transformative approach to inflammatory bowel disease (IBD) and other pathologies in which fatty acid amide hydrolase (show FAAH Antibodies)/cyclooxygenases (FAAH (show FAAH Antibodies), Cox-1, and Cox-2 (show COX2 Antibodies)) are overactive.

  10. In arteries from non-insulin (show INS Antibodies)-dependent diabetic mice, COX-1 remains a major contributor to the endothelial PGI2 (show PTGIR Antibodies) synthesis that evokes vasoconstrictor activity under the pathological condition.

Cow (Bovine) Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) interaction partners

  1. there was no expression of COX-1, either mRNA or protein, on any day of the estrous cycle

Human Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) interaction partners

  1. Results suggested that in Chinese Han patients with stroke taking aspirin for secondary prevention, PTGS1 polymorphisms may increase the risk of poor functional outcomes and this effect may be modulated by the smoking status. PTGS1 gene-smoking interaction might in part reflect the heterogeneity in the prognosis of patients treated with aspirin.

  2. analysis of co-existing variants in both F8 and PTGS-1 genes in a three-generation pedigree of hemophilia A; the PTGS-1 variant was associated with specific functional defects in the arachidonic acid pathway and more severe hemorrhage.

  3. Data suggest expression of PTGS1 in colon is significantly correlated with expression of PTGS2 (show PTGS2 Antibodies), PTGES1, PTGER2 (show PTGER2 Antibodies), and PTGER4 (show PTGER4 Antibodies); this study was conducted in individuals at high risk for colon cancer treated with Mediterranean diet versus a Healthy Eating diet for prevention of colon cancer. (PG = prostaglandin; PTGS2 (show PTGS2 Antibodies) = PG-endoperoxide synthase 2; PTGES1 = PGE (show LIPF Antibodies) synthase protein; PTGER2 (show PTGER2 Antibodies) = PGE (show LIPF Antibodies) receptor 2; PTGER4 (show PTGER4 Antibodies) = PGE (show LIPF Antibodies) receptor 4)

  4. Dimethyl ester of bilirubin exhibits anti-inflammatory activity through inhibition of secretory phospholipase A2 (show YWHAZ Antibodies), lipoxygenase and cyclooxygenase.

  5. Panax quinquefolium saponin attenuated HUVEC apoptosis and improved the dual antiplatelet-mediated reduction of platelet adhesion to injured HUVECs and the underlying mechanisms may be associated with PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) and COX (show COX8A Antibodies) pathways.

  6. The interactions of COX (show COX8A Antibodies)-1of rs3842787 and cox-2 (show COX2 Antibodies) of rs20417 were associated with aspirin resistance of stroke.

  7. We provide the first report that pro-angiogenic genes PECAM1 (show PECAM1 Antibodies), PTGS1, FGD5 (show FGD5 Antibodies), and MCAM (show MCAM Antibodies) may play a vital role in pathological dermal angiogenesis disorders of psoriasis.

  8. a new neutrophil-activating platelet-derived lipid generated by COX-1 (show COX1 Antibodies) is presented that can activate or prime human neutrophils, suggesting a role in innate immunity and acute inflammation.

  9. Seminal COX-1 (show COX1 Antibodies) is over-expressed in infertile oligoasthenoteratozoospermic (OAT (show OAT Antibodies)) men with varicocele (Vx) compared with fertile men with/without and infertile OAT (show OAT Antibodies) men without Vx being associated with oxidative stress, Vx grade and Vx laterality.

  10. In Indian peptic ulcer hemorrhage patients, those with Cox-1 (show COX1 Antibodies) A842G polymorphisms tended to have less gastric ulcers among those with the A842G/C50T polymorphism.

Pig (Porcine) Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1) interaction partners

  1. Brain death increases the expression of COX-1 (show COX1 Antibodies) and COX-2 (show PTGS2 Antibodies) mRNA in the renal medulla

  2. Endometrial prostaglandin-endoperoxide synthase 1 (PTGS1) mRNA expression increased 2- to 3-fold after Day 10 of the estrous cycle and pregnancy, whereas PTGS2 (show PTGS2 Antibodies) mRNA expression increased 76-fold between Days 5 and 15 of the estrous cycle and pregnancy.

PTGS1 Antigen Profile

Protein Summary

This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PTGS1

  • prostaglandin-endoperoxide synthase 1 (PTGS1) antibody
  • cyclooxygenase-1 (cox-1) antibody
  • prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (PTGS1) antibody
  • prostaglandin-endoperoxide synthase 1 (Ptgs1) antibody
  • prostaglandin-endoperoxide synthase 1 (ptgs1) antibody
  • prostaglandin-endoperoxide synthase 1 S homeolog (ptgs1.S) antibody
  • Cox-1 antibody
  • COX-3 antibody
  • cox1 antibody
  • COX3 antibody
  • PCOX1 antibody
  • PES-1 antibody
  • PGG/HS antibody
  • PGHS-1 antibody
  • PGHS1 antibody
  • PHS1 antibody
  • PHS 1 antibody
  • PTGHS antibody
  • Ptgs1 antibody
  • zCOX-1 antibody

Protein level used designations for PTGS1

cyclooxygenase-1 , prostaglandin G/H synthase 1 , prostaglandin G/H synthase and cyclooxygenase , prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) , PGH synthase 1 , PGHS-1 , PHS 1 , prostaglandin H2 synthase 1 , prostaglandin-endoperoxide synthase 1 , cyclooxygenase 1 , COX-1 , cyclooxygenase 3 , Cox-1 , Cox-1b , prostaglandin endoperoxide synthase , cyclooxygenase

GENE ID SPECIES
100034087 Equus caballus
100136038 Oncorhynchus mykiss
427752 Gallus gallus
464713 Pan troglodytes
698213 Macaca mulatta
100585600 Nomascus leucogenys
100009407 Oryctolagus cuniculus
19224 Mus musculus
24693 Rattus norvegicus
246226 Danio rerio
282022 Bos taurus
5742 Homo sapiens
443551 Ovis aries
403544 Canis lupus familiaris
397541 Sus scrofa
100037245 Xenopus laevis
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