PTGS1 antibody (AA 1-180)

Catalog No. ABIN6146413

The Rabbit Polyclonal anti-PTGS1 antibody (ABIN6146413) specifically detects PTGS1 in WB, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for PTGS1 antibody (AA 1-180) (ABIN6146413)

Target: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PTGS1 Antibody

Binding Specificity: AA 1-180

Sequence: MLMRLVLTVR SNLIPSPPTY NSAHDYISWE SFSNVSYYTR ILPSVPKDCP TPMGTKGKKQ LPDAQLLARR FLLRRKFIPD PQGTNLMFAF FAQHFTHQFF KTSGKMGPGF TKALGHGVDL GHIYGDNLER QYQLRLFKDG KLKYQVLDGE MYPPSVEEAP VLMHYPRGIP PQSQMAVGQE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human COX1/COX1/PTGS1 (NP_001258094.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PTGS1

Target: PTGS1 (Prostaglandin-Endoperoxide Synthase 1 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS1))

Alternative Name: PTGS1

Background: This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.,PTGS1,COX1,COX3,PCOX1,PES-1,PGG/HS,PGHS-1,PGHS1,PHS1,PTGHS,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,Blood,Heart,Cardiovascular diseases,Heart disease,PTGS1

Molecular Weight: 56 kDa/61 kDa/64 kDa/68 kDa/71 kDa/72 kDa

Gene ID: 5742

UniProt: P23219