anti-Protease, serine, 8 (PRSS8) Antibodies

PRSS8 encodes a trypsinogen, which is a member of the trypsin family of serine proteases. Additionally we are shipping Protease, serine, 8 Kits (38) and Protease, serine, 8 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PRSS8 5652 Q16651
PRSS8 192107 Q9ES87
PRSS8 76560  
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Top anti-Protease, serine, 8 Antibodies at antibodies-online.com

Showing 10 out of 101 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-PRSS8 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-PRSS8 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB   200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB PRSS8 Antibody (Center) (ABIN658128) western blot analysis in MDA-MB453 cell line lysates (35 µg/lane). This demonstrates the PRSS8 antibody detected the PRSS8 protein (arrow). 400 μL Log in to see 10 to 11 Days
$335.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Western Blot: Prostasin/Prss8 Antibody [NBP1-31592] - Sample(30 ug whole cell lysate) A:HeLa S3 B:Raji 10% SDS PAGE, antibody diluted at 1:1000. 100 μL Log in to see 8 to 11 Days
$514.63
Details
Guinea Pig Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), ELISA Immunochemical staining of human PRSS8 in human kidney with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). Immunochemical staining of human PRSS8 in human lung with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). 100 μg Log in to see 20 to 21 Days
$218.90
Details
Human Mouse Un-conjugated IP, ELISA, WB Immunoprecipitation of PRSS8 transfected lysate using anti-PRSS8 monoclonal antibody and Protein A Magnetic Bead , and immunoblotted with PRSS8 MaxPab rabbit polyclonal antibody. PRSS8 monoclonal antibody (M11A), clone 3C4. Western Blot analysis of PRSS8 expression in HepG2. 200 μL Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample(30 ug whole cell lysate) A:HeLa S3, B:Raji , 10% SDS PAGE antibody diluted at 1:1000 IHC-P Image Prostasin antibody [N1C2] detects Prostasin protein at cytosol on Ca922 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded Ca922 xenograft. Prostasin antibody [N1C2] , dilution: 1:250. 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti PRSS8 Polyclonal Antibody (ABIN761891), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human kidney labeled with Anti-PRSS8 Polyclonal Antibody, Unconjugated (ABIN761891) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$306.90
Details
Human Rabbit Un-conjugated WB Western blot analysis in MDA-MB453 cell line lysates (35ug/lane). 400 μL Log in to see 2 to 3 Days
$515.63
Details

Top referenced anti-Protease, serine, 8 Antibodies

  1. Human Polyclonal PRSS8 Primary Antibody for IHC, IHC (p) - ABIN441590 : Sherman-Baust, Becker, Wood Iii, Zhang, Morin: Gene expression and pathway analysis of ovarian cancer cells selected for resistance to cisplatin, paclitaxel, or doxorubicin. in Journal of ovarian research 2012 (PubMed)

More Antibodies against Protease, serine, 8 Interaction Partners

Human Protease, serine, 8 (PRSS8) interaction partners

  1. limited role for HAI-2 (show SPINT2 Antibodies) in the inhibition of matriptase (show ST14 Antibodies) and prostasin is the result of its primarily intracellular localization in basal and spinous layer keratinocytes, which probably prevents the Kunitz inhibitor from interacting with active prostasin or matriptase (show ST14 Antibodies)

  2. PRSS8 was downregulated in glioma tissues.PRSS8 role in the glioma cell proliferation, migration, and invasion.

  3. PRSS8 acts as a tumor suppressor in colorectal cancer

  4. Data show that PRSS8 was reduced in esophageal squamous cell carcinomas (ESCC) tissues and the reduction of PRSS8 was associated with poor differentiation and shorter survival time.

  5. Studies in colonic T84 cell monolayers revealed that barrier disruption by the colitis-associated Th2-type cytokines, IL-4 (show IL4 Antibodies) and IL-13 (show IL13 Antibodies), down-regulates matriptase (show ST14 Antibodies) as well as prostasin through phosphorylation of the transcriptional regulator STAT6 (show STAT6 Antibodies)

  6. PRSS8 may serve as a tumour suppressor in hepatocellular carcinoma progression.

  7. Overexpression of PRSS8 mRNA and high levels of prostasin in multiple subtypes of early stage ovarian tumors may provide clinical biomarkers for early detection of ovarian cancer.

  8. It is concluded that prostasin protein level change is less likely to be causally involved in placental dysfunction in preeclampsia.

  9. In urinary exosomes, NCC (show SLC12A3 Antibodies) and prostasin had a diurnal pattern parallel to ADH (show AVP Antibodies) and aquaporin 2 (show AQP2 Antibodies), confirming that, in healthy subjects, both prostasin and NCC (show SLC12A3 Antibodies) relate to water balance.

  10. Polymorphism of the prostasin gene is closely associated with poor pregnancy outcomes of early-onset severe preeclampsia.

Mouse (Murine) Protease, serine, 8 (PRSS8) interaction partners

  1. Studies in colonic T84 cell monolayers revealed that barrier disruption by the colitis-associated Th2-type cytokines, IL-4 (show IL4 Antibodies) and IL-13 (show IL13 Antibodies), down-regulates matriptase (show ST14 Antibodies) as well as prostasin through phosphorylation of the transcriptional regulator STAT6 (show STAT6 Antibodies)

  2. a proteolysis-dependent function of activated prostasin in hair follicles, dependent on zymogen conversion by matriptase (show ST14 Antibodies).

  3. The claudin-4 (show CLDN4 Antibodies)-mediated chloride conductance can be regulated endogenously by a protease-channel-activating protease 1 (cap1).

  4. HAI-1 (show SPINT1 Antibodies) regulates the activity of activated matriptase (show ST14 Antibodies), whereas HAI-2 (show SPINT2 Antibodies) has an essential role in regulating prostasin-dependent matriptase (show ST14 Antibodies) zymogen activation.

  5. a novel inhibitory interaction between CAP1/Prss8 and nexin-1 (show SERPINE2 Antibodies), opening the search for specific CAP1/Prss8 antagonists that are independent of its catalytic activity

  6. Data indicate that liver-specific serine protease (show F2 Antibodies) prostasin (PRSS8) knockout (LKO) mice develop insulin (show INS Antibodies) resistance associated with the increase in hepatic Toll-like receptor 4 (TLR4 (show TLR4 Antibodies)).

  7. Data indicate that serine protease (show F2 Antibodies) prostasin (CAP1/PRSS8) supports terminal epidermal differentiation through a non-catalytic mechanism.

  8. mutations in Prss8 restored placentation and normal development of HAI-1 (show SPINT1 Antibodies)-deficient embryos and prevented early embryonic lethality, mid-gestation lethality due to placental labyrinth failure, and neural tube defects in HAI-2 (show SPINT2 Antibodies)-deficient embryos.

  9. Mutations of the serine protease (show F2 Antibodies) CAP1/Prss8 lead to reduced embryonic viability, skin defects, and decreased ENaC (show SCNN1A Antibodies) activity.

  10. The T to A mutation at residue 170 (Val to Asp (show C3 Antibodies)) in Prss8 is responsible for the mutant frizzy (fr) phenotype.

Protease, serine, 8 (PRSS8) Antigen Profile

Protein Summary

This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine.

Gene names and symbols associated with PRSS8

  • protease, serine 8 (PRSS8) antibody
  • protease, serine, 8 (Prss8) antibody
  • protease, serine 8 (prostasin) (Prss8) antibody
  • protease, serine, 8 (PRSS8) antibody
  • protease, serine 36 (Prss36) antibody
  • 2410039E18Rik antibody
  • AI313909 antibody
  • C79772 antibody
  • CAP1 antibody
  • fr antibody
  • mCAP1 antibody
  • prostasin antibody
  • Prss8 antibody

Protein level used designations for PRSS8

channel-activating protease 1 , prostasin , serine protease 8 , channel activating protease 1 , polyserase-2 , protease, serine, 8

GENE ID SPECIES
5652 Homo sapiens
192107 Rattus norvegicus
613506 Bos taurus
76560 Mus musculus
102148278 Equus caballus
102157328 Canis lupus familiaris
100733736 Cavia porcellus
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