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PRSS8 Products

(Protease, serine, 8 (PRSS8))

Categories

This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine. [provided by RefSeq, Jul 2008].

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Featured PRSS8 Categories

PRSS8 Antibodies

High quality antibodies with extensive validation data.

PRSS8 ELISA Kits

Reliable ELISA kits for a wide range of species.

PRSS8 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PRSS8 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7436249
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IP
Validations
  • (7)
Cat. No. ABIN519337
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (3)
Cat. No. ABIN761891
Quantity 100 μL
Datasheet Datasheet

Recommended PRSS8 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6958891
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6974928
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969690
Quantity 96 tests
Datasheet Datasheet

Recommended PRSS8 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1316486
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316488
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7197548
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our PRSS8 products

Oxlund, Kurt, Schwarzensteiner, Hansen, Stæhr, Svenningsen, Jacobsen, Hansen, Thuesen, Toft, Hinrichs, Bistrup, Jensen: "Albuminuria is associated with an increased prostasin in urine while aldosterone has no direct effect on urine and kidney tissue abundance of prostasin." in: Pflügers Archiv : European journal of physiology, Vol. 469, Issue 5-6, pp. 655-667, (2018) (PubMed).

Zhang, Jia, Shi, Ge, Duan, Yang: "PRSS8 is Downregulated and Suppresses Tumour Growth and Metastases in Hepatocellular Carcinoma." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 40, Issue 3-4, pp. 757-769, (2016) (PubMed).

Andersen, Friis, Hansen, Svenningsen, Henriksen, Jensen: "Diabetic nephropathy is associated with increased urine excretion of proteases plasmin, prostasin and urokinase and activation of amiloride-sensitive current in collecting duct cells." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, (2015) (PubMed).

Yang, Zhang, Gong, Liu, Bai, Xu, Zhou: "Increased expression of prostasin contributes to early-onset severe preeclampsia through inhibiting trophoblast invasion." in: Journal of perinatology : official journal of the California Perinatal Association, Vol. 35, Issue 1, pp. 16-22, (2014) (PubMed).

Sherman-Baust, Becker, Wood Iii, Zhang, Morin: "Gene expression and pathway analysis of ovarian cancer cells selected for resistance to cisplatin, paclitaxel, or doxorubicin." in: Journal of ovarian research, Vol. 4, Issue 1, pp. 21, (2012) (PubMed).

Svenningsen, Uhrenholt, Palarasah, Skjødt, Jensen, Skøtt: "Prostasin-dependent activation of epithelial Na+ channels by low plasmin concentrations." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 297, Issue 6, pp. R1733-41, (2009) (PubMed).

Chen, Hodge, Guarda, Welch, Greenberg, Chai: "Down-regulation of prostasin serine protease: a potential invasion suppressor in prostate cancer." in: The Prostate, Vol. 48, Issue 2, pp. 93-103, (2001) (PubMed).

Chen, Skinner, Kauffman, Chao, Chao, Thaler, Chai: "Prostasin is a glycosylphosphatidylinositol-anchored active serine protease." in: The Journal of biological chemistry, Vol. 276, Issue 24, pp. 21434-42, (2001) (PubMed).

Yu, Chao, Chao: "Molecular cloning, tissue-specific expression, and cellular localization of human prostasin mRNA." in: The Journal of biological chemistry, Vol. 270, Issue 22, pp. 13483-9, (1995) (PubMed).

Yu, Chao, Chao: "Prostasin is a novel human serine proteinase from seminal fluid. Purification, tissue distribution, and localization in prostate gland." in: The Journal of biological chemistry, Vol. 269, Issue 29, pp. 18843-8, (1994) (PubMed).

Synonyms and alternative names related to PRSS8

protease, serine 8 (PRSS8), protease, serine, 8 (Prss8), protease, serine 8 (prostasin) (Prss8), protease, serine, 8 (PRSS8), 2410039E18Rik, AI313909, C79772, CAP1, fr, mCAP1, PROSTASIN, prostasin

Protein level used designations for PRSS8

  • channel-activating protease 1
  • prostasin
  • serine protease 8
  • channel activating protease 1
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