Protein Arginine Methyltransferase 1 Proteins (PRMT1)

PRMT1 encodes a member of the protein arginine N-methyltransferase (PRMT) family. Additionally we are shipping PRMT1 Antibodies (146) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PRMT1 3276 Q99873
Rat PRMT1 PRMT1 60421 Q63009
PRMT1 15469 Q9JIF0
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Top PRMT1 Proteins at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$547.80
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Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 13 to 16 Days
$242.00
Details
Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$315.00
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Escherichia coli (E. coli) Mouse Un-conjugated   50 μg Log in to see 2 to 3 Days
$315.00
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Escherichia coli (E. coli) Human His tag   50 μg Log in to see 4 Days
$385.00
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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Escherichia coli (E. coli) Human His-MBP 100 μg Log in to see 11 to 12 Days
$282.13
Details
Escherichia coli (E. coli) Human GST tag 100 μg Log in to see 11 Days
$411.40
Details

PRMT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , ,
, , , , ,
Mouse (Murine) ,
, ,

Top referenced PRMT1 Proteins

  1. Human PRMT1 Protein expressed in HEK-293 Cells - ABIN2729657 : Tikhanovich, Kuravi, Artigues, Villar, Dorko, Nawabi, Roberts, Weinman: Dynamic Arginine Methylation of Tumor Necrosis Factor (TNF) Receptor-associated Factor 6 Regulates Toll-like Receptor Signaling. in The Journal of biological chemistry 2015 (PubMed)

More Proteins for Protein Arginine Methyltransferase 1 (PRMT1) Interaction Partners

Human Protein Arginine Methyltransferase 1 (PRMT1) interaction partners

  1. Important roles of PRMT1 in progression of gastric cancer. Given the dual functions of PRMT1, it is as a potential drug target of gastric cancer with extreme caution.

  2. Mitochondrial Ca(2 (show CA2 Proteins)+) uptake is controlled by protein arginine methyl transferase 1 that asymmetrically methylates MICU1 (show MICU1 Proteins), resulting in decreased Ca(2 (show CA2 Proteins)+) sensitivity. UCP2 (show UCP2 Proteins)/3 normalize Ca(2 (show CA2 Proteins)+) sensitivity of methylated MICU1 (show MICU1 Proteins) and, thus, re-establish mitochondrial Ca(2 (show CA2 Proteins)+) uptake activity.

  3. High-PRMT1 expression is associated with resistance to cetuximab in triple-negative breast cancer.

  4. a significant role for PRMT1 in HCC (show FAM126A Proteins) progression and metastasis in vitro and in vivo via STAT3 (show STAT3 Proteins) signalling pathway activation. PRMT1 may be a potential novel prognostic biomarker and new therapeutic target for hepatocellular carcinoma.

  5. High PRMT1 expression is associated with head and neck and oral cancer.

  6. TRIM48 Promotes ASK1 (show MAP3K5 Proteins) Activation and Cell Death through Ubiquitination-Dependent Degradation of the ASK1 (show MAP3K5 Proteins)-Negative Regulator PRMT1

  7. data collectively suggest that silencing of PRMT1 exerts anti-catabolic and anti-inflammatory effects on IL-1beta (show IL1B Proteins)-induced chondrocytes via suppressing the Gli-1 (show GLI1 Proteins) mediated Hedgehog (show SHH Proteins) signaling pathway, indicating that PRMT1 plays a critical role in OA development and serves as a promising therapeutic target for OA.

  8. Deacetylation on both K200 and K205 by Sirtuin 1 (Sirt1 (show SIRT1 Proteins)) and acetylation of p300 (EP300 (show EP300 Proteins)) on K205 collaboratively prepare the motif for SCF (show KITLG Proteins)(Fbxl17 (show FBXL17 Proteins)) binding thereby triggering PRMT1 protein degradation.

  9. PRMT1 has a role in regulating MYCN (show MYCN Proteins) in neuroblastoma (show ARHGEF16 Proteins)

  10. Analysis of deletion constructs of SERBP1 (show SERBP1 Proteins) showed that the C-terminal third of the SERBP1 (show SERBP1 Proteins) protein, which contains one of its two substrate sites for protein arginine N-methyltransferase 1 (PRMT1), is necessary and sufficient for it to interact with RACK1 (show GNB2L1 Proteins)

Zebrafish Protein Arginine Methyltransferase 1 (PRMT1) interaction partners

  1. prmt8 (show PRMT8 Proteins) may play important roles non-overlapping with prmt1 in embryonic and neural development depending on its specific N-terminus.

  2. prmt1 gene is actively and ubiquitously expressed at both RNA and protein levels at the early developmental stages of zebrafish.

Xenopus laevis Protein Arginine Methyltransferase 1 (PRMT1) interaction partners

  1. PRMT1 functions transiently as a coactivator in thyroid hormone (show PTH Proteins) (T3) receptor (TR)-mediated transcription by enhancing TR-T3 response element binding and further suggest that PRMT1 has tissue-specific roles in regulating the rate of metamorphosis.

Pig (Porcine) Protein Arginine Methyltransferase 1 (PRMT1) interaction partners

  1. Results suggest that part of the type I arginine methyltransferases in brains, mainly PRMT1, are sequestered in an inactive form as they associated with membranes or large subcellular complexes.

Mouse (Murine) Protein Arginine Methyltransferase 1 (PRMT1) interaction partners

  1. the present study increases our understanding of PRMT1, -4, and -5 biology during the plasticity of skeletal muscle development. Our results provide evidence for a role of PRMT1, via a mitochondrially mediated mechanism, in driving the muscle differentiation program.

  2. lipotoxicity-induced PRMT1 expression promotes endoplasmic reticulum stress-mediated mesangial cell apoptosis.

  3. PRMT1 is an arginine methyltransferase involved in a variety of cell functions. Here the authors delete PRMT1 specifically in mature B cells to show the importance of arginine methylation for B cell proliferation, differentiation and survival, and thereby for humoral immunity.

  4. Collectively, this study firstly demonstrated that PRMT1 exert podocyte-injury effects in mouse glomerulus through Ang (show ANG Proteins) /ERK (show EPHB2 Proteins) pathway, which reveals a potential therapeutic target for DN.

  5. PRMT1 inhibition prevents gastric cancer progression by downregulating eIF4E (show EIF4E Proteins) and targeting type II PRMT5 (show PRMT5 Proteins).

  6. Low Prmt1 expression is associated with osteosarcoma.

  7. Collectively, the authors propose that Prmt1-dependent facilitation of KCNQ (show KCNQ1 Proteins)-phosphatidylinositol-4,5-bisphosphate interaction underlies the positive regulation of KCNQ (show KCNQ1 Proteins) activity by arginine methylation, which may serve as a key target for prevention of neuronal hyperexcitability and seizures.

  8. Results identify a key molecular mechanism by which the BTG2 (show BTG2 Proteins)-PRMT1 module regulates pre-B cell differentiation and inhibits pre-B cell leukemogenesis.

  9. Data, including data from studies in cells from knockout mice, suggest that Prmt1 activity was necessary for c-Myc (show MYC Proteins) binding to acetyltransferase p300 (show NOTCH1 Proteins) in myeloid cells; Prmt1 inhibition decreases p300 (show NOTCH1 Proteins) recruitment to c-Myc (show MYC Proteins) target promoters and increased Hdac1 (show HDAC1 Proteins) recruitment. [Prmt1, protein arginine N-methyltransferase 1; c-Myc (show MYC Proteins) = Proto-Oncogene (show RAB1A Proteins) Proteins c-myc (show MYC Proteins); Hdac1 (show HDAC1 Proteins) = histone deacetylase 1 (show HDAC1 Proteins)]

  10. PRMT1-dependent regulation of macrophage PPARgamma (show PPARG Proteins) expression contributes to the infection susceptibility in PRMT1 knock-out mice

PRMT1 Protein Profile

Protein Summary

This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.

Gene names and symbols associated with PRMT1

  • protein arginine methyltransferase 1A (PRMT1A)
  • protein arginine N-methyltransferase-1 (prm-1)
  • protein arginine N-methyltransferase 1 (EDI_007800)
  • protein arginine N-methyltransferase 1 (Smp_029240.3)
  • protein arginine methyltransferase 1 (prmt1)
  • protein arginine N-methyltransferase (PRMT1)
  • protein arginine methyltransferase (prmt1)
  • protein arginine methyltransferase 1 (PRMT1)
  • protein arginine methyltransferase 1 S homeolog (prmt1.S)
  • protein arginine methyltransferase 1 (Prmt1)
  • protein arginine N-methyltransferase 1 (Prmt1)
  • 3E10 protein
  • 6720434D09Rik protein
  • anm1 protein
  • ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 1A protein
  • ATPRMT1A protein
  • AW214366 protein
  • DDBDRAFT_0183976 protein
  • DDBDRAFT_0235399 protein
  • DDB_0183976 protein
  • DDB_0235399 protein
  • DKFZp459J1326 protein
  • F6F22.30 protein
  • F6F22_30 protein
  • fb39h07 protein
  • hcp1 protein
  • Hrmt1l2 protein
  • ir1b4 protein
  • Mrmt1 protein
  • PRMT1 protein
  • protein arginine methyltransferase 1A protein
  • wu:fb39h07 protein
  • xPRMT1 protein
  • xPRMT1b protein
  • zf1 protein
  • zgc:66201 protein

Protein level used designations for PRMT1

protein arginine N-methyltransferase 1 , protein arginine methyltransferase 1 , protein arginine N-methyltransferase , HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2 , heterogeneous nuclear ribonucleoprotein methyltransferase 1-like 2 , histone-arginine N-methyltransferase PRMT1 , interferon receptor 1-bound protein 4 , HMT1 hnRNP methyltransferase-like 2 , histone-arginine N-methyltransferase PRMT1-A , protein arginine N-methyltransferase 1-A , heterogeneous nuclear ribonucleoproteins methyltransferase-like 2 , arginine N-methyltransferase 1

GENE ID SPECIES
816486 Arabidopsis thaliana
3880059 Neurospora crassa OR74A
5880968 Entamoeba dispar SAW760
8347013 Schistosoma mansoni
100194598 Salmo salar
5728909 Chlamydomonas reinhardtii
8628232 Dictyostelium discoideum AX4
100052097 Equus caballus
100173232 Pongo abelii
3276 Homo sapiens
321974 Danio rerio
399121 Xenopus laevis
476411 Canis lupus familiaris
520388 Bos taurus
60421 Rattus norvegicus
100286877 Sus scrofa
15469 Mus musculus
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