anti-Protein C Receptor, Endothelial (PROCR) Antibodies

The protein encoded by PROCR is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. Additionally we are shipping PROCR Kits (65) and PROCR Proteins (31) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PROCR 10544 Q9UNN8
PROCR 362248 Q4V8I1
PROCR 19124 Q64695
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Top anti-PROCR Antibodies at antibodies-online.com

Showing 10 out of 173 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Biotin FACS, IHC, WB EPCR in Human Liver. EPCR was detected in immersion fixed paraffin-embedded sections of human liver array using Goat Anti-Human EPCR Biotinylated Antigen Affinity-purified Polyclonal Antibody. Lower panel shows a lack of labeling if primary antibodies are omitted and tissue is stained only with secondary antibody followed by incubation with detection reagents. 50 μg Log in to see 8 to 9 Days
$446.20
Details
Human Rabbit Un-conjugated WB Western Blot: EPCR Antibody [NBP2-21578] - A. 30 ug HeLa whole cell lysate/extract12 % SDS-PAGEEPCR antibody dilution: 1:1000. Western Blot: EPCR Antibody [NBP2-21578] - Sample (30 ug of whole cell lysate) A: JC B: BCL-1 12% SDS PAGE gel, diluted at 1:1000. 0.1 mL Log in to see 8 to 11 Days
$514.63
Details
Human Goat Un-conjugated CyTOF, FACS, IHC, WB Detection of Human EPCR by Western Blot. Western blot shows lysates of human skin tissue, human placenta tissue, and HUVEC human umbilical vein endothelial cells. PVDF membrane was probed with 0.25 ug/mL of Goat Anti-Human EPCR Antigen Affinity-purified Polyclonal Antibody. This experiment was conducted under reducing conditions. EPCR in Human Liver. EPCR was detected in immersion fixed paraffin-embedded sections of human liver using 1.7 µ 100 μg Log in to see 8 to 9 Days
$416.30
Details
Mouse Goat Un-conjugated CyTOF, FACS, ICC, IP, WB Detection of EPCR in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endothelioma cell line was stained with Goat Anti-Mouse EPCR Antigen Affinity-purified Polyclonal Antibody. Detection of Mouse EPCR by Western Blot. Western blot shows lysates of bEnd.3 mouse endothelioma cell line. PVDF membrane was probed with 0.5 ug/mL of Goat Anti-Mouse EPCR Antigen Affinity-purified Polyclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Log in to see 8 to 9 Days
$440.45
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to PROCR on formalin-fixed paraffin-embedded human malignant lymphoma, diffuse large B tissue. [antibody concentration 3 ug/ml] Immunofluorescence of monoclonal antibody to PROCR on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Rat Rabbit Un-conjugated ICC, IHC, WB Figure. DAB staining on IHC-P; Samples: Rat Testis Tissue. 100 μg Log in to see 15 to 18 Days
$342.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of CD201 antibody (Center) (ABIN389416) in T47D cell line lysates (35 µg/lane). CD201 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human lung carcinoma with CD201 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB Western Blot (WB) analysis of Rat barin lysis using CD201 antibody. 100 μL Log in to see 16 Days
$181.73
Details
Cow Rabbit Un-conjugated WB   200 μL Log in to see 13 to 14 Days
$487.50
Details

PROCR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PROCR Antibodies

  1. Human Monoclonal PROCR Primary Antibody for IF, IHC (p) - ABIN564600 : Lee, Ku, Bae: Emodin-6-O-?-D-glucoside down-regulates endothelial protein C receptor shedding. in Archives of pharmacal research 2013 (PubMed)
    Show all 6 Pubmed References

  2. Human Polyclonal PROCR Primary Antibody for CyTOF, FACS - ABIN4899324 : Ducros, Berthaut, Mirshahi, Faussat, Soria, Agarwal, Mirshahi: Aldosterone modifies hemostasis via upregulation of the protein-C receptor in human vascular endothelium. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 5 Pubmed References

  3. Mouse (Murine) Polyclonal PROCR Primary Antibody for CyTOF, FACS - ABIN4899294 : Greineder, Chacko, Zaytsev, Zern, Carnemolla, Hood, Han, Ding, Esmon, Muzykantov: Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor. in PLoS ONE 2013 (PubMed)
    Show all 5 Pubmed References

  4. Human Monoclonal PROCR Primary Antibody for Func, FACS - ABIN2192007 : Dömötör, Benzakour, Griffin, Yule, Fukudome, Zlokovic: Activated protein C alters cytosolic calcium flux in human brain endothelium via binding to endothelial protein C receptor and activation of protease activated receptor-1. in Blood 2003 (PubMed)
    Show all 5 Pubmed References

  5. Human Monoclonal PROCR Primary Antibody for Func, FACS - ABIN2192008 : Ye, Fukudome, Tsuneyoshi, Satoh, Tokunaga, Sugawara, Mizokami, Kimoto: The endothelial cell protein C receptor (EPCR) functions as a primary receptor for protein C activation on endothelial cells in arteries, veins, and capillaries. in Biochemical and biophysical research communications 1999 (PubMed)
    Show all 5 Pubmed References

  6. Human Polyclonal PROCR Primary Antibody for WB - ABIN4270023 : Gera, Shavit-Stein, Bushi, Harnof, Shimon, Weiss, Golderman, Dori, Maggio, Finegold, Chapman: Thrombin and protein C pathway in peripheral nerve Schwann cells. in Neuroscience 2016 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal PROCR Primary Antibody for FACS - ABIN2689080 : Biguzzi, Merati, Liaw, Bucciarelli, Oganesyan, Qu, Gu, Fetiveau, Esmon, Mannucci, Faioni: A 23bp insertion in the endothelial protein C receptor (EPCR) gene impairs EPCR function. in Thrombosis and haemostasis 2001 (PubMed)
    Show all 2 Pubmed References

  8. Human Monoclonal PROCR Primary Antibody for BP, FACS - ABIN269970 : Schut, Kirschbaum, Adelmeijer, de Groot, Lisman: In vitro uptake of recombinant factor VIIa by megakaryocytes with subsequent production of platelets containing functionally active drug. in British journal of haematology 2016 (PubMed)

  9. Human Polyclonal PROCR Primary Antibody for WB - ABIN523963 : Ku, Kim, Bae: Piperlonguminine downregulates endothelial protein C receptor shedding in vitro and in vivo. in Inflammation 2014 (PubMed)

  10. Human Polyclonal PROCR Primary Antibody for FACS, IHC - ABIN4899323 : Gunawardana, Kuk, Smith, Batruch, Soosaipillai, Diamandis: Comprehensive analysis of conditioned media from ovarian cancer cell lines identifies novel candidate markers of epithelial ovarian cancer. in Journal of proteome research 2009 (PubMed)

More Antibodies against PROCR Interaction Partners

Human Protein C Receptor, Endothelial (PROCR) interaction partners

  1. Plasma levels of Ang2 (show ANGPT2 Antibodies) were associated with markers of malaria severity and levels of var transcripts encoding P. falciparum Erythrocyte Membrane Protein 1 (PfEMP1) containing Cysteine Rich Inter Domain Region alpha1 (CIDRalpha1) domains predicted to bind Endothelial Protein C receptor (EPCR).

  2. The EPCR rs867186-GG genotype is associated with increased soluble protein, and it could mediate protection against severe malaria.

  3. The data indicate that EPCR can regulate p63 (show RPE65 Antibodies), is associated with highly proliferative keratinocytes, and is a potential human epidermal stem cell marker.

  4. Analysis of a cohort of breast cancer patients revealed an association of high EPCR levels with adverse clinical outcome. Interestingly, EPCR knockdown did not affect cell growth kinetics in 2D but reduced cell growth in 3D cultures. EPCR silencing reduced primary tumor growth and secondary outgrowths at metastatic sites. EPCR via SPOCK1 (show SPOCK1 Antibodies) confers a cell growth advantage in 3D promoting breast tumorigenesis and metastasis.

  5. analysis of renal endothelial PROCR expression and shedding during diabetic nephropathy

  6. EPCR occupancy recruits G-protein coupled receptor kinase 5 (show GRK5 Antibodies), thereby inducing beta-arrestin-2 (show ARRB2 Antibodies) biased PAR1 (show MARK2 Antibodies) signaling by both APC (show APC Antibodies) and thrombin (show F2 Antibodies). In

  7. EPCR polymorphisms may be associated with increased risk of sepsis, but this has no effect on the release of soluble EPCR in patients with sepsis.

  8. Elevated endothelium-related mediators (vWF (show VWF Antibodies), E-selectin (show SELE Antibodies) and EPCR) appear to participate in the development of pancreatic necrosis and may be a potential indicator of overall prognosis.

  9. The results showed that AS-IV could significantly inhibit PMA-induced EPCR shedding.

  10. CORM-2 protects human umbilical vein endothelial cells from lipopolysaccharide-induced injury, by way of suppressing NF-kappaB (show NFKB1 Antibodies) activity, which downregulates TM and EPCR mRNAs. It also decreases MMP-2 (show MMP2 Antibodies) expression and prevents the shedding of TM and EPCR from the surface of endothelial cells, so as to preserve their protective effect.

Mouse (Murine) Protein C Receptor, Endothelial (PROCR) interaction partners

  1. Leu8 (show SELL Antibodies) is crucial for FVIIa-EPCR binding; this study characterizes its interaction in vivo in mice

  2. PROCR thus does not globally inhibit Th17 responses but could be targeted to selectively inhibit proinflammatory Th17 cells.

  3. Thrombin (show F2 Antibodies)-PAR1 (show F2R Antibodies) signaling, via nitric oxide and EPCR, promotes hematopoietic stem cell (HSC (show FUT1 Antibodies)) mobilization. aPC (show APC Antibodies)-EPCR-PAR1 (show F2R Antibodies) signaling promotes HSC (show FUT1 Antibodies) retention in bone marrow.

  4. impaired EPCR/protein C (show PROC Antibodies)-binding interactions not only result in procoagulant and proinflammatory effects, but also impact hematopoiesis

  5. sPLA2 (show PLA2G2A Antibodies)-V plays a thrombogenic role by impairing the ability of EPCR to promote protein C (show PROC Antibodies) activation.

  6. HSCs appear to maintain expression of CD201 after hematopoietic injury when Kit expression is downregulated.

  7. The protein C (show PROC Antibodies) receptor (ProcR; EPCR) was required for the normal in vivo and in vitro induction of lipopolysaccharide (LPS (show TLR4 Antibodies))-regulated gene expression.

  8. Data indicate that endothelial protein C receptor (EPCR) binding enhances FVIIa hemostatic activity in vivo.

  9. protein C (show PROC Antibodies) receptor (Procr), a novel Wnt (show WNT2 Antibodies) target in the mammary gland, marks a unique population of multipotent mouse mammary stem cells

  10. FVIIa binding to EPCR leads to a barrier protective effect in vivo

PROCR Antigen Profile

Protein Summary

The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy.

Gene names and symbols associated with PROCR

  • protein C receptor (PROCR) antibody
  • protein C receptor (Procr) antibody
  • protein C receptor, endothelial (Procr) antibody
  • AI325044 antibody
  • Ccca antibody
  • Ccd41 antibody
  • Epcr antibody
  • PROCR antibody

Protein level used designations for PROCR

protein C receptor, endothelial (EPCR) , APC receptor , CD201 antigen , activated protein C receptor , cell cycle, centrosome-associated protein , centrocyclin , endothelial protein C receptor , endothelial cell protein C receptor , CD antigen CD201 , centrosomal protein CCD41 , endothelial cell protein C/activated protein C

GENE ID SPECIES
458198 Pan troglodytes
10544 Homo sapiens
362248 Rattus norvegicus
19124 Mus musculus
100731547 Cavia porcellus
654289 Sus scrofa
282005 Bos taurus
485848 Canis lupus familiaris
424867 Gallus gallus
101115814 Ovis aries
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