anti-Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B) Antibodies

Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1. Additionally we are shipping Protein Geranylgeranyltransferase Type I, beta Subunit Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PGGT1B 5229 P53609
PGGT1B 81746 P53610
PGGT1B 225467 Q8BUY9
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Top anti-Protein Geranylgeranyltransferase Type I, beta Subunit Antibodies at antibodies-online.com

Showing 10 out of 35 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  Pggt1b  Sample Type:  Rat Small Intestine lysates  Antibody Dilution:  1.0ug/ml 100 μL 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated ELISA, IF, IHC, IHC (p), WB 100 μg 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB PGGT1B monoclonal antibody (M02), clone 5E4 Western Blot analysis of PGGT1B expression in HeLa . Immunofluorescence of monoclonal antibody to PGGT1B on HeLa cell. [antibody concentration 10 ug/ml] 100 μg 11 to 12 Days
$440.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.66 KDa) . 50 μL 11 to 12 Days
$305.71
Details
Human Rabbit Cy5.5 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Cy3 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Cy7 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Cy5 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL 14 to 21 Days
$416.90
Details
Human Rabbit FITC IF (p)   100 μL 14 to 21 Days
$416.90
Details

Top referenced anti-Protein Geranylgeranyltransferase Type I, beta Subunit Antibodies

  1. Human Polyclonal PGGT1B Primary Antibody for ELISA, WB - ABIN562193 : Iguchi, Katsuno, Niwa, Yamada, Sone, Waza, Adachi, Tanaka, Nagata, Arimura, Watanabe, Kaibuchi, Sobue: TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases. in The Journal of biological chemistry 2009 (PubMed)

  2. Human Monoclonal PGGT1B Primary Antibody for IF, IHC (p) - ABIN562194 : Lee, Chang, Trinh, Tu, White, Davies, Bergo, Fong, Lowry, Young: Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes. in Human molecular genetics 2010 (PubMed)

More Antibodies against Protein Geranylgeranyltransferase Type I, beta Subunit Interaction Partners

Human Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B) interaction partners

  1. our study showed, for the first time, that HIF-1alpha was regulated by protein prenylation transferase GGTI and mediated the effect of GGTI on glioma cell migration and invasion

  2. our findings identify Geranylgeranyl transferase 1 as a key regulator of human airway smooth muscle cell viability

  3. RNAi knockdown of GGTase-Ibeta inhibited invasion, disrupted F-actin organization and decreased the level of cofilin in PC-3 cells.

  4. results suggest that geranylgeranylation of RhoA is critical for cancer cell invasion

  5. Results suggest that all peptide substrates adopt a common binding mode in the protein farnesyltransferase and geranylgeranyltransferase active site.

Mouse (Murine) Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B) interaction partners

  1. The results showed that the magnitude of long-term potentiation (LTP) was markedly suppressed in hippocampal slices from GGT-haplodeficient mice. Consistent with the synaptic dysfunction, there was a significant decrease in cortical spine density and cognitive function in GGT-haplodeficient mice.

  2. This study demonstrated that Inhibiting geranylgeranyltransferase I activity decreases spine density in central nervous system.

  3. A decrease in membrane-associated Rho proteins in aged brain is associated with down-regulation of GGTase-Ibeta.

  4. Targeting GGTase-I activates RHOA and leads to increased macrophage reverse cholesterol transport and reduced atherosclerosis development despite a significant increase in inflammation.

  5. deficiencies in either FTase or GGTase-I lead to severe hepatocellular disease. Our studies lay to rest the earlier notion that FTase is dispensable in adult tissues

  6. Data show that mice lacking GGTase-I in macrophages develop severe joint inflammation resembling erosive rheumatoid arthritis.

  7. Both Fntb and Pggt1b are required for the homeostasis of skin keratinocytes.

Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B) Antigen Profile

Protein Summary

Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994

Gene names and symbols associated with PGGT1B

  • protein geranylgeranyltransferase type I subunit beta (PGGT1B) antibody
  • protein geranylgeranyltransferase type I, beta subunit S homeolog (pggt1b.S) antibody
  • protein geranylgeranyltransferase type 1 subunit beta (Pggt1b) antibody
  • protein geranylgeranyltransferase type I, beta subunit (Pggt1b) antibody
  • 2010207C17Rik antibody
  • 2610100E13 antibody
  • AI451237 antibody
  • AI551093 antibody
  • BGG1 antibody
  • BGGI antibody
  • GGT1 antibody
  • GGTI antibody
  • MGC115505 antibody

Protein level used designations for PGGT1B

protein geranylgeranyltransferase type I, beta subunit , GGTase-I-beta , geranylgeranyl transferase type I subunit beta , geranylgeranyl transferase type-1 subunit beta , geranylgeranyltransferase type I beta subunit , type I protein geranyl-geranyltransferase subunit beta , geranylgeranyltransferase type 1 beta , geranylgeranyltransferase type I (GGTase-I)

GENE ID SPECIES
770633 Gallus gallus
481440 Canis lupus familiaris
734580 Xenopus laevis
5229 Homo sapiens
81746 Rattus norvegicus
225467 Mus musculus
509322 Bos taurus
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