PGGT1B antibody (AbBy Fluor® 680)

Catalog No. ABIN5008723

The Rabbit Polyclonal anti-PGGT1B antibody is suitable to detect PGGT1B in samples from Human, Rat and Mouse. It has been validated for WB and IF (p).

Quick Overview for PGGT1B antibody (AbBy Fluor® 680) (ABIN5008723)

Target: PGGT1B (Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGGT1B antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-PGGT1B Antibody (AbBy Fluor® 680)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PGGT1 beta

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PGGT1B

Target: PGGT1B (Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B))

Alternative Name: PGGT1B

Background:

Synonyms: PGGT1B, GGTase-I beta, GGTase-1 beta, BGGI, Geranylgeranyl transferase type I subunit beta, Geranylgeranyl transferase type-1 subunit beta, GGTase-I-beta, GGTI, PGGT1B, PGTB1_HUMAN, Type I protein geranyl-geranyltransferase subunit beta,

Background: Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA, MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010]

Gene ID: 5229