PGGT1B antibody

Catalog No. ABIN1385395

This Rabbit Polyclonal antibody specifically detects PGGT1B in WB, IF (p) and IHC (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for PGGT1B antibody (ABIN1385395)

Target: PGGT1B (Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGGT1B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PGGT1B Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PGGT1 beta

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PGGT1B

Target: PGGT1B (Protein Geranylgeranyltransferase Type I, beta Subunit (PGGT1B))

Alternative Name: PGGT1B

Background:

Synonyms: PGGT1B, GGTase-I beta, GGTase-1 beta, BGGI, Geranylgeranyl transferase type I subunit beta, Geranylgeranyl transferase type-1 subunit beta, GGTase-I-beta, GGTI, PGGT1B, PGTB1_HUMAN, Type I protein geranyl-geranyltransferase subunit beta,

Background: Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA, MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010]

Gene ID: 5229