anti-Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) Antibodies

PACSIN2 is a member of the protein kinase C and casein kinase substrate in neurons family. Additionally we are shipping PACSIN2 Proteins (9) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PACSIN2 11252 Q9UNF0
PACSIN2 23970 Q9WVE8
PACSIN2 124461 Q9QY17
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Top anti-PACSIN2 Antibodies at antibodies-online.com

Showing 10 out of 66 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image PACSIN2 antibody [N2C3] detects PACSIN2 protein at cytosol on human colon carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human colon carcinoma. PACSIN2 antibody [N2C3] , dilution: 1:500. WB Image Sample (30 ug of whole cell lysate) A: NT2D1 B: U87-MG 7.5% SDS PAGE antibody diluted at 1:1000 100 μL 3 to 4 Days
$466.18
Details
Chicken Rabbit Un-conjugated IHC (p), WB 50 μg 6 to 8 Days
$495.00
Details
Chicken Rabbit Un-conjugated IHC, IHC (p), WB Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with PACSIN2 antibody ABIN293028 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-PACSIN2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μg 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB   0.4 mL 4 to 8 Days
$522.50
Details
Human Mouse Un-conjugated ELISA, IHC, IHC (p), WB 100 μg 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated IF, IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to PACSIN2 on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml] Detection limit for recombinant GST tagged PACSIN2 is 0.1 ng/ml as a capture antibody. 100 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of mouse heart and mouse lung cell lines, using PACSIN2 antibody. 100 μL 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Immunohistochemical analysis of paraffin-embedded H. stomach section using PACSIN2 Antibody . Antibody was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining. Immunohistochemical analysis of paraffin-embedded H.stomach section using PACSIN2 Antibody . Antibody was diluted at 1:100 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining. 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cells, using PACSIN2 antibody. 100 μL 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using PACSIN2 antibody. 200 μL 12 to 14 Days
$438.90
Details

Top referenced anti-PACSIN2 Antibodies

  1. Human Polyclonal PACSIN2 Primary Antibody for IHC (p), ELISA - ABIN544259 : Ritter, Modregger, Paulsson, Plomann: PACSIN 2, a novel member of the PACSIN family of cytoplasmic adapter proteins. in FEBS letters 1999 (PubMed)
    Show all 3 Pubmed References

More Antibodies against PACSIN2 Interaction Partners

Human Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) interaction partners

  1. Pacsin2 recruitment is important for maintenance of cell-cell adhesion by stabilizing the VE-cadherin complex within focal adherens junctions and inhibition of its internalization.

  2. observations indicate that PACSIN2 promotes the cell-to-cell spreading of HIV-1 by connecting Gag to the actin cytoskeleton.

  3. To our knowledge, this is the first study showing PACSIN2 genotype association with hematological toxicity in ALL patients undergoing maintenance therapy.

  4. FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets.

  5. our results provide new insights into the mechanism of cellular intoxication by TcdA and the role of PACSIN2 in endocytosis.

  6. proposed a packing model for the assembly of PACSIN 2 on membrane, where the proteins are connected by tip-to-tip and wedge loop-mediated lateral interactions on the surface of membrane to generate various diameter tubules

  7. PACSIN2 phosphorylation decreases its membrane-binding activity, thereby decreasing its stabilizing effect on caveolae and triggering dynamin-mediated removal of caveolae.

  8. PC1 modulates actin cytoskeleton rearrangements and directional cell migration through the Pacsin 2/N-Wasp complex.

  9. Cooperation of MICAL-L1, pacsin 2 (syndapin2), and phosphatidic acid in tubular recycling endosome biogenesis.

  10. These data indicate that polymorphism in PACSIN2 significantly modulates TPMT activity and influences the risk of GI toxicity associated with mercaptopurine therapy.

  11. a novel role for the F-BAR-domain protein PACSIN2 in regulating EGF receptor surface levels and EGF-induced downstream signaling.

  12. important role in the formation of plasma membrane caveolae

  13. Data identify the BAR-domain protein PACSIN2 as a Rac1 interactor that regulates Rac1-mediated cell spreading and migration.

  14. PACSIN2 regulates cell spreading and cell migration, which are dependent on cyclin D1 expression.

  15. Results indicate that PACSIN2 mediates membrane sculpting by caveolin-1 in caveola morphology and recruits dynamin-2 for caveola fission.

  16. Since the curvature of the neck of the microspike and that of the tubulation share similar geometry, the pacsin2 EFC/F-BAR domain is considered to facilitate both microspike formation and tubulation.

  17. Thus, syndapin-dynamin complexes are crucial and sufficient to promote vesicle formation from the trans-Golgi network.

  18. These findings suggest a novel function for PACSIN proteins 1, 2, and 3 in dynamic microtubule nucleation.

  19. The regulated deformation of membranes and promotion of tubule constrictions by Pacsin suggests a more versatile function of these proteins in vesiculation and endocytosis.

Mouse (Murine) Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) interaction partners

  1. Pacsin 2 is necessary for cardiac development and function in mouse embryos.

  2. Pacsin 2 contributes to kidney development and repair in a nephron-specific manner.

  3. syndapin II binds to both flat and curved membranes in vivo and that it plays an important role in caveolar shaping, a role that it shares with PTRF/cavin 1.

  4. important role in the formation of plasma membrane caveolae

  5. These findings suggest a novel function for PACSIN proteins 1, 2, and 3 in dynamic microtubule nucleation.

Xenopus laevis Protein Kinase C and Casein Kinase Substrate in Neurons 2 (PACSIN2) interaction partners

  1. Study shows that PACSIN2 is involved in the regulation of gastrulation, possibly through regulating cell adhesion.

PACSIN2 Antigen Profile

Protein Summary

This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation by regulating tubulin polymerization. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PACSIN2

  • protein kinase C and casein kinase substrate in neurons 2 (pacsin2) antibody
  • protein kinase C and casein kinase substrate in neurons 2 (PACSIN2) antibody
  • protein kinase C and casein kinase substrate in neurons 2 (Pacsin2) antibody
  • protein kinase C and casein kinase substrate in neurons 2 S homeolog (pacsin2.S) antibody
  • AI197433 antibody
  • DKFZp459J1025 antibody
  • PACSIN2 antibody
  • SdpII antibody
  • zgc:77519 antibody

Protein level used designations for PACSIN2

protein kinase C and casein kinase substrate in neurons 2 , protein kinase C and casein kinase substrate in neurons protein 2-like , cytoplasmic phosphoprotein PACSIN2 , protein kinase C and casein kinase substrate in neurons protein 2 , syndapin 2 , syndapin II , syndapin-II , syndapin2 , Syndapin II , x-PACSIN2 , FAP52 , focal adhesion protein of 52 kDa , p52 , SdpIIsyndapin II , protein kinase C and casein kinase substrate in neurons 2 protein , synaptic dynamin-associated protein II

GENE ID SPECIES
404601 Danio rerio
711242 Macaca mulatta
100056169 Equus caballus
100173238 Pongo abelii
100231673 Taeniopygia guttata
100400703 Callithrix jacchus
100585150 Nomascus leucogenys
11252 Homo sapiens
23970 Mus musculus
398138 Xenopus laevis
395975 Gallus gallus
470231 Pan troglodytes
100683200 Canis lupus familiaris
540107 Bos taurus
124461 Rattus norvegicus
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