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PACSIN3 is a member of the protein kinase C and casein kinase substrate in neurons family.
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Human Polyclonal PACSIN3 Primary Antibody for ELISA - ABIN257701
Cuajungco, Grimm, Oshima, Dhoedt, Nilius, Mensenkamp, Bindels, Plomann, Heller: PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4. in The Journal of biological chemistry 2006
These data confirm linkage between directional migration, endocytosis and cell specification during embryonic morphogenesis and highlight a key role for Pacsin3 in this coupling in the notochord.
Show that in neuroendocrine chromaffin cells fusion pore expansion and catecholamine release are limited specifically by mutation of syndapin (show PACSIN1 Antibodies) 3.
Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules
PACSIN3 has a novel function as an up-regulator in the signaling of proHB-EGF (show EGF Antibodies) shedding induced by TPA (show PLAT Antibodies) and angiotensin II
PACSIN 3 acts as an auxiliary protein of TRPV4 (show TRPV4 Antibodies) channel that not only affects the channel's subcellular localization but also modulates its function in a stimulus-specific manner.
crystal of PACSIN 3 (1-341) diffracted to 2.6 A resolution and belonged to space group P2(1), with unit-cell parameters a = 46.9, b = 54.7, c = 193.7 A, alpha = 90, beta = 96.9, gamma = 90 degrees
PACSIN 3 specifically affects the endocytosis of TRPV4 (show TRPV4 Antibodies), thereby modulating the subcellular localization
These results establish a role for PACSIN3 in regulating glucose uptake in adipocytes via its preferential participation in GLUT1 (show SLC2A1 Antibodies) trafficking.
This gene is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation. Alternative splicing results in multiple transcript variants.
, protein kinase C and casein kinase substrate in neurons 3
, putative protein kinase C and casein kinase substrate in neurons 3 variant 1
, protein kinase C and casein kinase substrate in neurons protein 3-like
, SH3 domain-containing protein 6511
, protein kinase C and casein kinase substrate in neurons protein 3
, syndapin III
, protein kinase C and casein kinase II substrate protein 3