Ras Association (RalGDS/AF-6) Domain Family Member 2 Proteins (RASSF2)

RASSF2 encodes a protein that contains a Ras association domain. Additionally we are shipping RASSF2 Antibodies (51) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RASSF2 215653 Q8BMS9
RASSF2 311437 Q3B7D5
RASSF2 9770 P50749
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Top RASSF2 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,370.21
Details
Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$5,370.21
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 11 Days
$888.80
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,876.50
Details

RASSF2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , ,
, ,

More Proteins for Ras Association (RalGDS/AF-6) Domain Family Member 2 (RASSF2) Interaction Partners

Mouse (Murine) Ras Association (RalGDS/AF-6) Domain Family Member 2 (RASSF2) interaction partners

  1. These observations indicate that RASSF2 regulates osteoblast and osteoclast differentiation by inhibiting NF-kappaB signalling via association with IkappaB kinase (IKK) alpha and beta forms and suppression of IKK activity.

Pig (Porcine) Ras Association (RalGDS/AF-6) Domain Family Member 2 (RASSF2) interaction partners

  1. The K-Ras-specific effector and potential tumor suppressor gene RASSF2 contains a breed-specific expressed tranversion polymorphism as confirmed in day 25 Meishan and white composite swine placentae.

Human Ras Association (RalGDS/AF-6) Domain Family Member 2 (RASSF2) interaction partners

  1. Results showed that in the endometrial adenocarcinoma (OEA group) and ovarian clear cell carcinoma (OCC group) groups, the methylation degrees of the RASSF2A promoter were obviously higher than that of the other two groups. The expression level of RASSF2A mRNA in the OEA and OCC groups was lower than that of the other two groups.

  2. we confirmed that the RASSF2-PAR-4 axis was mainly responsible for miR-7 functions in CAFs using bioinformatics methods. Overexpression of miR-7 in CAFs led to down-regulation of RASSF2, which dramatically decreased the secretion of PAR-4 from CAFs and then enhanced the proliferation and migration of the co-cultured cancer cells.

  3. Results suggest that down-regulation of RASSF2, and RASSF6 is a tumor-specific phenomenon and their inactivation through CpG island methylation may play important roles in gastric cardia carcinogenesis.

  4. The statistically most significant association rs4813720 correlates with RASSF2 expression and may play a significant role in childhood ALL etiology.

  5. RASSF2 may be an important molecular marker for carcinogenesis, prognosis and progression in gastric cancer

  6. RASSF2 gene is differently methylated in luminal and non-luminal tumors and is a promising suppressor gene with clinical involvement in breast cancer

  7. our results suggest that RASSF2 may function as a tumor suppressor gene

  8. We conclude that EPB41L3, RASSF2 and TSP-1 genes are involved in the pathogenesis of diffuse gliomas

  9. Promoter hypermethylation of RASSF2A is observed in cervical cancer, while not in normal cervical tissues.

  10. Epigenetic inactivation of RASSF2A through aberrant promoter methylation may play an important role in the pathogenesis of epithelial ovarian cancer.

  11. results suggest that both RASSF1A and RASSF2 are novel epigenetically inactivated tumor suppressor genes in Ewing sarcoma and RASSF2 methylation may have prognostic implications for ES patients

  12. our results suggest that RASSF2 potentially functions as a new tumor-suppressor gene that is inactivated through hypermethylation in cervical cancer

  13. Promoter hypermethylation of RASSF2A is observed in pancreatic ductal adenocarcinoma, while not in normal pancreatic tissue.

  14. Hypermethylation of RASSF2 gene is associated with advanced gastric cancer.

  15. Sp1-mediated RASSF2A gene transcription is activated by p300 through histone acetylation, and this activation plays an important role in inducing late apoptosis.

  16. Results suggest that RASSF2 encodes a novel epigenetically inactivated candidate tumor suppressor gene in thyroid carcinogenesis.

  17. Aberrant methylation of the RASSF2A gene with the subsequent loss of RASSF2A expression plays an important role in the pathogenesis of hepatocellular carcinoma.

  18. Data show that RASSF2 forms a direct and endogenous complex with prostate apoptosis response protein 4 (PAR-4) and that this interaction is regulated by K-Ras and is essential for the full apoptotic effects of PAR-4.

  19. these findings indicate that MST1 is a major determinant of RASSF2 protein stability, and suggest that RASSF2 acts in a complex manner that extends beyond simple protein-protein association to play an important role in MST1 regulation.

  20. RASSF2 is a new member of the RASSF1 family of Ras effectors/tumor suppressors that exhibits a specificity for interacting with K-Ras

RASSF2 Protein Profile

Protein Summary

This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported.

Gene names and symbols associated with RASSF2

  • Ras association (RalGDS/AF-6) domain family member 2 (Rassf2)
  • Ras association domain family member 2 (RASSF2)
  • Ras association domain family member 2 (Rassf2)
  • Ras association domain family member 2 (rassf2)
  • Ras association (RalGDS/AF-6) domain family member 2b (rassf2b)
  • 3830431H01Rik protein
  • 9030412M04Rik protein
  • AI852669 protein
  • AW495050 protein
  • CENP-34 protein
  • MGC107807 protein
  • RASFADIN protein
  • RASSF2 protein
  • rassf2l protein
  • zgc:91855 protein

Protein level used designations for RASSF2

Ras association (RalGDS/AF-6) domain family 2 , ras association domain-containing protein 2 , Ras association domain family 2 , Ras association (RalGDS/AF-6) domain family member 2 , Ras association (RalGDS/AF-6) domain family 2, like , rassf2 , Ras association domain-containing protein 2 , ras association domain-containing protein 2-like , centromere protein 34

GENE ID SPECIES
215653 Mus musculus
282337 Bos taurus
311437 Rattus norvegicus
419521 Gallus gallus
458077 Pan troglodytes
485781 Canis lupus familiaris
548420 Xenopus (Silurana) tropicalis
718924 Macaca mulatta
100006341 Danio rerio
100157105 Sus scrofa
100399551 Callithrix jacchus
100458150 Pongo abelii
100473558 Ailuropoda melanoleuca
100589906 Nomascus leucogenys
9770 Homo sapiens
100714425 Cavia porcellus
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