anti-Receptor-Interacting Serine-threonine Kinase 4 (RIPK4) Antibodies

The protein encoded by RIPK4 is a serine/threonine protein kinase that interacts with protein kinase C-delta. Additionally we are shipping RIPK4 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RIPK4 54101  
RIPK4 72388 Q9ERK0
RIPK4 304053  
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Top anti-RIPK4 Antibodies at antibodies-online.com

Showing 10 out of 62 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RIPK4 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Human heart 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RIPK4 Antibody Titration:  0.2-1 ug/ml  Positive Control:  293T cell lysate Host:  Rabbit  Target Name:  RIPK4  Sample Tissue:  Human HT1080 Whole Cell  Antibody Dilution:  1ug/ml 100 μL 2 to 3 Days
$319.00
Details
Guinea Pig Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$581.17
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ANKRD3-Q817 Pab (ABIN392243) in mouse kidney tissue lysate (35 µg/lane). ANKRD3-Q817(arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL 10 to 11 Days
$385.00
Details
Human Mouse Un-conjugated ELISA, FACS, WB Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western blot analysis using RIPK4 mAb against human RIPK4 (AA: 675-784) recombinant protein. (Expected MW is 37.7 kDa) 0.1 mg 3 to 4 Days
$430.10
Details
Bat Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB RIPK4 monoclonal antibody (M05), clone 2D1 Western Blot analysis of RIPK4 expression in A-431 . Immunoperoxidase of monoclonal antibody to RIPK4 on formalin-fixed paraffin-embedded human liver. [antibody concentration 3 ug/ml] 100 μg 11 to 12 Days
$440.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated WB Immunohistochemistry of paraffin-embedded human liver injury using RIPK4 antibody at dilution of 1:100 (x40 lens). Immunohistochemistry of paraffin-embedded human gastric using RIPK4 antibody at dilution of 1:100 (x40 lens). 100 μL 11 to 13 Days
$366.77
Details
Human Mouse Un-conjugated ELISA, WB 100 μg 11 to 14 Days
$537.17
Details

Top referenced anti-RIPK4 Antibodies

  1. Human Monoclonal RIPK4 Primary Antibody for ELISA, WB - ABIN565712 : Adams, Munz: RIP4 is a target of multiple signal transduction pathways in keratinocytes: implications for epidermal differentiation and cutaneous wound repair. in Experimental cell research 2009 (PubMed)

  2. Human Polyclonal RIPK4 Primary Antibody for IHC (p), ELISA - ABIN544435 : Hattori, Fujiyama, Taylor, Watanabe, Yada, Park, Toyoda, Ishii, Totoki, Choi, Groner, Soeda, Ohki, Takagi, Sakaki, Taudien, Blechschmidt, Polley, Menzel, Delabar, Kumpf, Lehmann, Patterson, Reichwald et al.: The DNA sequence of human chromosome 21. ... in Nature 2000 (PubMed)

More Antibodies against RIPK4 Interaction Partners

Human Receptor-Interacting Serine-threonine Kinase 4 (RIPK4) interaction partners

  1. Taken together, these findings indicate that IL-17 increased RIP4-mediated STAT3 phosphorylation by directly interacting with STAT3. Thus, transcriptional activation of STAT3 promotes the expression of CCL20. Thus, activations of these signalling pathways by RIP4 may contribute to epithermal inflammation in psoriatic keratinocytes.

  2. Data highlighted the molecular aetiology and clinical significance of RIPK4 in BC: upregulation of RIPK4 contributes to NF-kappaB activation, and upregulates VEGF-A, and BC progression.

  3. This study demonstrated the oncogenic roles of RIPK4 in nasopharyngeal carcinoma.

  4. Data show that the SCF(beta-TrCP) ubiquitin E3 ligase complex responsible for regulating the active protein kinase C-associated kinase (RIPK4) level.

  5. Silencing RIPK4 promoted the proliferation and inhibited the apoptosis of chondrocytes. In addition, silencing RIPK4 blocked the Wnt/betacatenin signaling pathway, thus contributing to alleviating the osteoarthritis pathogenesis.

  6. RIPK4 was upregulated in the subgroup of pancreatic cancer with a high metastatic potential

  7. A20 regulates canonical wnt-signaling through an interaction with RIPK4

  8. that loss of RIP4 enhances STAT3 signaling in lung cancer cells

  9. The patient with CHAND syndrome harbored the same mutation as the one identified in the family previously reported. We thus confirm the implication of RIPK4 gene in CHAND syndrome in addition to Bartsocas-Papas syndrome and discuss genotype/phenotype correlations.

  10. CCL5 and CXCL11 expression were also induced in response to the activation of the PKC pathway, and gene silencing experiments indicated that their inducible expression was dependent on RIPK4 and IRF6. Moreover, gene reporter assays suggested that RIPK4 induces CCL5 and CXCL11 expression by stimulating the transactivation of their promoters by IRF6.

  11. Overexpression of EZH2 was found in 30 patients (76.9%) and was associated with FIGO stage, histological type, and lymph node metastasis (p < 0.05). In conclusion, our data suggest that RIPK4/EZH2 markers might be used as potential predictors of prognosis in cervical cancer.

  12. These findings position RIPK4 upstream of a hierarchal IRF6-GRHL3-ELF3 transcription factor pathway in keratinocytes.

  13. CHAND and Bartsocas-Papas syndrome might be allelic disorders or RIPK4 mutations could confer varying degrees of phenotypic severity, depending on their localization within or outside functionally important domains.

  14. we identified an epithelial ovarian cancer susceptibility loci at 10p11.21 (rs1192691 near ANKRD30A, P(meta) = 2.62 x 10(-8))

  15. The p.Ser376X mutation in RIPK4 impaired its induction of IRF6 transactivator function.

  16. Suppression of PKK expression by RNA interference inhibits phosphorylation of IKKalpha and IKKbeta as well as activation of NF-kappaB in human cancer cell lines; thus, PKK regulates NF-kappaB activation by modulating activation of IKKalpha and IKKbeta.

  17. The protein kinase C-associated kinase (PKK), which is also known as the receptor-interacting protein kinase 4, is a suppressor of tumor growth in squamous cell carcinoma of the skin.

  18. Data indicate protein-serine-threonine kinases RIPK4 overexpression in transformed fetal hepatocytes.

  19. Authors found a correlation between RIPK4 expression and TSCC degree of differentiation, age, and gender.

  20. Ser-413 and Ser-424 in IRF6 are important for its activation by RIPK4

Mouse (Murine) Receptor-Interacting Serine-threonine Kinase 4 (RIPK4) interaction partners

  1. Study of keratinocyte-specific RIPK4 knockout (KO) mice found that RIPK4 in keratinocytes is essential for the establishment of a functional inside-out skin barrier but is not required for the formation of a functional outside-in barrier during development. In addition, we show that epithelial fusions in RIPK4 full KO mice are E-cadherin dependent.

  2. Study presents the first crystal structure of Ripk4 and uses a structure- and biochemistry-guided approach to demonstrate that the Ripk4 homodimer is essential for catalytic activity.

  3. We further define the interactions of keratinocyte PKK with TP63 and NF-kappaB signaling, highlighting the importance of this protein as a tumor suppressor in skin squamous cell carcinoma development.

  4. this work uncovers a critical role of PKK in lupus development

  5. these results reveal a critical role of PKK in the maintenance of recirculating mature B cells as well as the development of B1 cells in mice

  6. This approach identified a key signaling event, phosphorylation of a desmosome component, PKP1 (plakophilin-1) by RIPK4 (receptor-interacting serine-threonine kinase 4) during epidermal differentiation.

  7. RIP4 functions in the epidermis through PKC-specific signaling pathways to regulate differentiation and inflammation

  8. a member of the RICK/RIP family of kinases, which is involved in a PKC-activated NF-kappa B signaling pathway that is independent of Bcl10 and IKK gamma

  9. Data show that RIP4 is a critical component of a novel pathway that controls keratinocyte differentiation.

  10. PKK may be required early in B cell development and for B cell receptor-mediated B cell proliferation.

  11. PKK is not required for the production of B cells in the bone marrow or for the development and maintenance of all mature B lymphocyte populations.

  12. NF-kappaB activity and keratinocyte differentiation are regulated by the RIP4 protein, which has roles in cutaneous wound repair

RIPK4 Antigen Profile

Protein Summary

The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation.

Gene names and symbols associated with RIPK4

  • receptor interacting serine/threonine kinase 4 L homeolog (ripk4.L) antibody
  • receptor-interacting serine-threonine kinase 4 (ripk4) antibody
  • receptor interacting serine/threonine kinase 4 (RIPK4) antibody
  • receptor interacting serine/threonine kinase 4 S homeolog (ripk4.S) antibody
  • receptor interacting serine/threonine kinase 4 (ripk4) antibody
  • receptor-interacting serine-threonine kinase 4 (Ripk4) antibody
  • 2310069J12Rik antibody
  • AI552420 antibody
  • ANKK2 antibody
  • Ankrd3 antibody
  • DIk antibody
  • MGC53701 antibody
  • MGC132134 antibody
  • NKRD3 antibody
  • PKK antibody
  • PPS2 antibody
  • RIP4 antibody
  • RIPK4 antibody
  • ripk4a antibody
  • ripk4b antibody
  • wu:fj80b10 antibody
  • zgc:55705 antibody

Protein level used designations for RIPK4

ankyrin repeat domain 3 , protein kinase PKK , receptor-interacting serine/threonine-protein kinase 4 , receptor-interacting serine-threonine kinase 4 , receptor-interacting serine/threonine-protein kinase 4-like , PKC-delta-interacting protein kinase , ankyrin repeat domain-containing protein 3 , protein kinase C-associated kinase , serine/threonine-protein kinase ANKRD3 , PKC-associated protein kinase , PKC-regulated protein kinase

GENE ID SPECIES
380107 Xenopus laevis
406351 Danio rerio
418529 Gallus gallus
444073 Xenopus laevis
470094 Pan troglodytes
487772 Canis lupus familiaris
715077 Macaca mulatta
733737 Xenopus (Silurana) tropicalis
100016114 Monodelphis domestica
100080436 Ornithorhynchus anatinus
100195444 Salmo salar
100446068 Pongo abelii
100473893 Ailuropoda melanoleuca
54101 Homo sapiens
72388 Mus musculus
508668 Bos taurus
304053 Rattus norvegicus
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