SATB Homeobox 2 Proteins (SATB2)

SATB2 encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. Additionally we are shipping SATB2 Antibodies (77) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SATB2 23314 Q9UPW6
Rat SATB2 SATB2 501145  
SATB2 212712 Q8VI24
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Top SATB2 Proteins at

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 70 Days
Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days

SATB2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
Mouse (Murine)

Top referenced SATB2 Proteins

  1. Human SATB2 Protein expressed in Wheat germ - ABIN2752928 : Nodin, Johannesson, Wangefjord, OConnor, Lindquist, Uhlén, Jirström, Eberhard: Molecular correlates and prognostic significance of SATB1 expression in colorectal cancer. in Diagnostic pathology 2012 (PubMed)

More Proteins for SATB Homeobox 2 (SATB2) Interaction Partners

Human SATB Homeobox 2 (SATB2) interaction partners

  1. There was a negative correlation between the expression levels of SATB2 and miR-34a.

  2. A shift in the function of SATB2 in cortex over lifetime.

  3. SATB2 is a useful marker for determining the primary sites of metastatic Krukenberg tumors of the ovary.

  4. miR-3666 was reported to be downregulated in CRC tissues and overexpression of miR-3666 impaired the proliferation, migration and invasion of CRC cells by targeting SATB2 in the present study.

  5. Study provides evidence that the molecular mechanisms that underpin schizophrenia and cognitive function include disruption of biological processes influenced by SATB2 as the brain is being organized and wired during development.

  6. the associations between the cleft palate (CPO) and single nucleotide polymorphisms (SNPs) of special AT-rich sequence-binding protein 2 (SATB2), were investigated.

  7. The Autism spectrum disorder candidate genes SATB2, CHD8 and EHMT1 show enriched expression in neurons, especially inhibitory neurons

  8. up-regulation of miR-31 may underlie endothelial dysfunction in diabetes by targeting Satb2

  9. SATB2 as an additional diagnostic marker for the diagnosis of an ovarian manifestation of low-grade appendiceal mucinous neoplasm

  10. HNF4-alpha and particularly SATB2 may be helpful in the differential diagnosis of pulmonary adenocarcinoma and metastases of colorectal adenocarcinomas

  11. The study identified that decreased expression of SATB2 was correlated with tumor progression and poor prognosis in non-small cell lung cancer (NSCLC) patients. Furthermore, SATB2 suppressed lung cancer cell invasion and metastasis and regulated the expression of EMT-related proteins and histone methylation by G9a.

  12. this study shows that SATB2 is a diagnostic marker of sinonasal intestinal-type adenocarcinoma

  13. SATB2 could serve as a promising diagnostic biomarker of colorectal cancer metastases.

  14. SATB2 can be used as a supplementary marker along with CDX2 to identify 'colon-rectum' as the primary site in material from patients presenting with metastasis.

  15. We describe the phenotype and genotype of 12 individuals with 10 unique (de novo in 11 of 11 tested) pathogenic variants (1 splice site, 5 frameshift, 3 nonsense, and 2 missense) in SATB2 and review all cases reported in the published literature caused by point alterations thus far

  16. features associated with de novo mutations affecting SATB2 function in individuals ascertained on the basis of intellectual disability

  17. The mRNA level of SATB2 was lower in tumor tissues than in samples of corresponding unchanged kidney. The results of the presented study suggest the tumor-suppressing function of SATB2.

  18. MiR-875-5pdirectly binds to the 3'untranslated region of SATB.2

  19. These results strongly suggest that SATB2 prevents induction of EMT by suppressing expression of EMT-inducing transcription factors in NSCLC cells.

  20. We describe here the identification of a de novo SATB2 point mutation in twin boys with cleft soft palate, dental anomalies, and development delay and compare the clinical presentation of SATB2 point mutation patients reported to date.

Mouse (Murine) SATB Homeobox 2 (SATB2) interaction partners

  1. Together, these findings demonstrate that Satb2 is critically involved in long-term plasticity processes in the adult forebrain that underlie the consolidation and stabilization of context-linked memory.

  2. Satb2 is a genetic determinant that mediates proper circuit development in a core sensory-to-motor spinal network.

  3. Data indicate two special AT-rich sequence-binding protein 2 (SATB2) sequence variants in two unrelated patients presenting with Rett-like phenotypes.

  4. results suggest that expression of Sp7 during the early stage of Satb2-induced osteogenic differentiation of BMSCs is regulated by miR-27a.

  5. Data show that Satb2 is required by both callosal projection neurons and subcerebral projection neurons for proper differentiation and axon pathfinding.

  6. Satb2 and Fezf2 regulation promotes subcerebral projection neuron identity in the developing cerebral cortex

  7. Satb2 may also be related to the establishment of species-specific neuropeptide co-phenotypes during postnatal development.

  8. Target genes of miR-27a ware significantly up-regulated in Satb2-overexpressing cells.

  9. A comprehensive overview of Satb2 expression in the adult mouse brain.

  10. The Satb2 proteins are dispensable for X chromosome inactivation in mice.

  11. the CB(1) receptor contributes to the generation of deep-layer cortical neurons by coupling endocannabinoid signals from the neurogenic niche to the intrinsic proneurogenic Ctip2/Satb2 axis

  12. Our results indicate a cell autonomous and non-cell autonomous role for Satb2 in regulating the adhesive and/or repulsive properties of cerebral pyramidal neurons.

  13. Genetic evidence obtained in the mouse confirmed the importance of SATB2 regulation by miR-34b/c

  14. SATB2 may play a crucial role in protecting against oxidative stress-induced osteoblast apoptosis.

  15. Satb2 recruits Ski to the Ctip2 locus, and Ski attracts histone deacetylases, thereby enabling the formation of a functional nucleosome remodeling and deacetylase repressor complex.

  16. The transcription factor Satb2 is expressed by cortical neurons extending axons through the corpus callosum and is a determinant of callosal versus subcortical projection.

  17. in SATB2-overexpressed MC3T3-E1 cells,genes closely associated with osteoblast differentiation were identified.

  18. SATB2 as the first p63 binding partner that differentially influences AEC and EEC p63 mutant proteins

  19. Osx is an upstream regulator of Satb2 during bone formation.

  20. SATB2 acts as a potent transcription factor to enhance osteoblastogenesis and promote bone regeneration.

SATB2 Protein Profile

Protein Summary

This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.

Gene names and symbols associated with SATB Homeobox 2 Proteins (SATB2)

  • SATB homeobox 2 (SATB2)
  • SATB homeobox 2 (satb2)
  • SATB homeobox 2 (Satb2)
  • special AT-rich sequence binding protein 2 (Satb2)
  • mKIAA1034 protein
  • RGD1562369 protein

Protein level used designations for SATB Homeobox 2 Proteins (SATB2)

DNA-binding protein SATB2 , special AT-rich sequence-binding protein 2 , special AT-rich sequence binding protein , SATB homeobox 2 , special AT-rich sequence binding protein 2 , SATB family member 2 , KIAA1034-like DNA binding protein , two cut domains-containing homeodomain protein

100070721 Equus caballus
424063 Gallus gallus
699151 Macaca mulatta
100029787 Monodelphis domestica
100229961 Taeniopygia guttata
100387368 Callithrix jacchus
100448381 Pongo abelii
100469819 Ailuropoda melanoleuca
100494002 Xenopus (Silurana) tropicalis
100548343 Meleagris gallopavo
100582076 Nomascus leucogenys
23314 Homo sapiens
501145 Rattus norvegicus
541192 Bos taurus
212712 Mus musculus
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