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SARS-CoV-2 Spike Proteins

(SARS-CoV-2 Spike)
mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
SARS-CoV-2 Spike (Super Stable Trimer) protein (His tag) SARS-CoV-2 Spike (Super Stable Trimer) protein (His tag) SARS-CoV-2 Spike (Super Stable Trimer) protein (His tag) (ABIN6953302)

Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-MALS. ELISA

SARS-CoV-2 Spike (B.1.351 - beta) protein (rho-1D4 tag) SARS-CoV-2 Spike (B.1.351 - beta) protein (rho-1D4 tag) SARS-CoV-2 Spike (B.1.351 - beta) protein (rho-1D4 tag) (ABIN6963740)

Origin: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta Host: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE ELISA, LBA

SARS-CoV-2 Spike (Trimer) protein (rho-1D4 tag) SARS-CoV-2 Spike (Trimer) protein (rho-1D4 tag) SARS-CoV-2 Spike (Trimer) protein (rho-1D4 tag) (ABIN6952670)

Origin: SARS Coronavirus-2 (SARS-CoV-2) Host: HEK-293 Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB

SARS-CoV-2 Spike Proteins by Grade

Find SARS-CoV-2 Spike Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

SARS-CoV-2 Spike Proteins by Origin

Find SARS-CoV-2 Spike Proteins for a variety of species such as anti-SARS Coronavirus-2 (SARS-CoV-2) SARS-CoV-2 Spike, anti-SARS CoV-2 Omicron SARS-CoV-2 Spike, anti-SARS CoV-2 Delta SARS-CoV-2 Spike. The species listed below are among those available. Click on a link to go to the corresponding products.

SARS-CoV-2 Spike Proteins by Source

Find SARS-CoV-2 Spike Proteins with a specific Source. The Source listed below are among those available. Click on a link to go to the corresponding products.

SARS-CoV-2 Spike Proteins by Protein Type

Find SARS-CoV-2 Spike Proteins with a specific Protein Type. The Protein Type listed below are among those available. Click on a link to go to the corresponding products.

SARS-CoV-2 Spike Proteins by Application

Find SARS-CoV-2 Spike Proteins validated for a specific application such as ELISA, LBA, SDS, WB. Some of the available applications are listed below. Click on a link to go to the corresponding products.

SARS-CoV-2 Spike Proteins by Biological Activity

Find SARS-CoV-2 Spike Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular SARS-CoV-2 Spike Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity SARS CoV-2 Alpha, SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (1)
  • (4)
Cat. No. ABIN6963742
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS CoV-2 Gamma, SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (1)
  • (4)
Cat. No. ABIN6964443
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN6953299
Quantity 200 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN6961147
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS CoV-2 Omicron, SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7041433
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS CoV-2 Kappa, SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN6976302
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS CoV-2 Omicron, SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (1)
  • (3)
Cat. No. ABIN7041436
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS CoV-2 Omicron, SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7072153
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (1)
  • (3)
Cat. No. ABIN7013267
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN6953301
Quantity 50 μg
Datasheet Datasheet
Reactivity SARS CoV-2 Alpha, SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (1)
  • (3)
Cat. No. ABIN7013275
Quantity 50 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN6953300
Quantity 200 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN6953303
Quantity 200 μg
Datasheet Datasheet
Reactivity SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (1)
  • (2)
Cat. No. ABIN6961175
Quantity 100 μg
Datasheet Datasheet
Reactivity SARS CoV-2 Eta, SARS Coronavirus-2 (SARS-CoV-2)
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN6972924
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our SARS-CoV-2 Spike Proteins

Bohnacker, Hartung, Henkel, Quaranta, Kolmert, Priller, Ud-Dean, Giglberger, Kugler, Pechtold, Yazici, Lechner, Erber, Protzer, Lingor, Knolle, Chaker, Schmidt-Weber, Wheelock, Esser-von Bieren: "Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages." in: , Vol. 15, Issue 3, pp. 515-524, (2022) (PubMed).

Bhalla, Payam, Morelli, Sharma, Johnson, Thomson, Jolly, Canfarotta: "Nanoplasmonic biosensor for rapid detection of multiple viral variants in human serum." in: Sensors and actuators. B, Chemical, Vol. 365, pp. 131906, (2022) (PubMed).

Vogt, Augusto, Martina, Chang, Nasrallah, Speiser, Vogel, Bachmann, Mohsen: "Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron." in: Vaccines, Vol. 10, Issue 5, (2022) (PubMed).

Wu, Wu, Wang, Liu, Chu, Jiang, Kwong, Chow, Li, Chen: "Microfluidic particle dam for direct visualization of SARS-CoV-2 antibody levels in COVID-19 vaccinees." in: Science advances, Vol. 8, Issue 22, pp. eabn6064, (2022) (PubMed).

Arunachalam, Feng, Ashraf, Hu, Walls, Edara, Zarnitsyna, Aye, Golden, Miranda, Green, Threeton, Maness, Beddingfield, Bohm, Scheuermann, Goff, Dufour, Russell-Lodrigue, Kepl, Fiala, Wrenn et al.: "Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine. ..." in: Science translational medicine, Vol. 14, Issue 658, pp. eabq4130, (2022) (PubMed).

Yokoyama, Ichiki: "Nano-size dependence in the adsorption by the SARS-CoV-2 spike protein over gold colloid." in: Colloids and surfaces. A, Physicochemical and engineering aspects, Vol. 615, pp. 126275, (2021) (PubMed).

Alves Ferreira-Bravo, DeStefano: "Xeno-Nucleic Acid (XNA) 2'-Fluoro-Arabino Nucleic Acid (FANA) Aptamers to the Receptor-Binding Domain of SARS-CoV-2 S Protein Block ACE2 Binding." in: Viruses, Vol. 13, Issue 10, (2021) (PubMed).

Longworth, Dittmar: "An antigen microarray protocol for COVID-19 serological analysis." in: STAR protocols, Vol. 2, Issue 3, pp. 100815, (2021) (PubMed).

Ropa, Cooper, Capitano, Vant Hof, Broxmeyer: "Human Hematopoietic Stem, Progenitor, and Immune Cells Respond Ex Vivo to SARS-CoV-2 Spike Protein." in: Stem cell reviews and reports, (2020) (PubMed).

Wei, Wan, Yan, Wang, Zhang, Yang, Zhang, Fan, Li, Deng, Sun, Gong, Yang, Wang, Wang, Li, Yang, Li, Zhang, Wang, Du, Zong, Yin, Zhang, Wang, Peng, Lin, Feng, Qin, Chen, Gao, Zhang, Cao, Zhong: "HDL-scavenger receptor B type 1 facilitates SARS-CoV-2 entry." in: Nature metabolism, Vol. 2, Issue 12, pp. 1391-1400, (2020) (PubMed).

Aliases for SARS-CoV-2 Spike Proteins

E2 glycoprotein precursor (S) Proteins
Surface Glycoprotein (S) Proteins
E2 Proteins
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