SH3-Domain Binding Protein 5 (BTK-Associated) Proteins (SH3BP5)

may bind c-Jun N-terminal kinase (JNK)\; may play a role in JNK and Bruton's tyrosine kinase (Btk) mediated signaling pathways [RGD, Feb 2006].. Additionally we are shipping SH3-Domain Binding Protein 5 (BTK-Associated) Antibodies (28) and SH3-Domain Binding Protein 5 (BTK-Associated) Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SH3BP5 9467 O60239
SH3BP5 24056 Q9Z131
SH3BP5 117186 Q91Y80
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Top SH3-Domain Binding Protein 5 (BTK-Associated) Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,626.73
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,626.73
Details
Wheat germ Human GST tag 10 μg 11 to 12 Days
$414.29
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$888.80
Details
Insect cells (Sf9) Human DYKDDDDK Tag Validation with Western Blot 20 μg 11 Days
$518.10
Details
Yeast Rat His tag   1 mg 60 to 71 Days
$3,285.33
Details

SH3BP5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine)

Rat (Rattus)

More Proteins for SH3-Domain Binding Protein 5 (BTK-Associated) (SH3BP5) Interaction Partners

Human SH3-Domain Binding Protein 5 (BTK-Associated) (SH3BP5) interaction partners

  1. SH3 domain binding protein 5 (Sab) expression is reduced in ovarian cancer (OC), suggesting that Sab may be a prognostic biomarker to discern personalized treatments for OC patients.

  2. SH3BP5, LMO3, and SNAP25 were expressed in diffuse large B-cell lymphoma cells and associated with clinical features.

  3. REI/SH3BP5 protein family is conserved in evolution and is a group of new guanine nucleotide exchange factors for Rab11.

  4. The interplay of p-JNK with mitochondrial Sab leads to impaired respiration, ROS production, sustained JNK activation, and apoptosis.

  5. SH3BP5 binds to JNK and directly inhibits JNK through its two putative mitogen-activated protein kinase interaction motifs (KIMs).

  6. mitochondrial protein Sab is phosphorylated by stress-activated protein kinase 3

Mouse (Murine) SH3-Domain Binding Protein 5 (BTK-Associated) (SH3BP5) interaction partners

  1. The binding to and phosphorylation of Sab by p-JNK on the outer mitochondrial membrane leads to SHP1-dependent and DOK4-dependent inactivation of p-Src on the inner membrane; inactivation of mitochondrial Src inhibits electron transport and increases reactive oxygen species release, which sustains JNK activation and promotes cell death and organ injury.

  2. The interplay of p-JNK with mitochondrial Sab leads to impaired respiration, ROS production, sustained JNK activation, and apoptosis.

  3. ER stress triggers an interaction of JNK with mitochondrial Sab, which leads to impaired respiration and increased mitochondrial reactive oxygen species.

  4. SH3BP5 binds to JNK and directly inhibits JNK through its two putative mitogen-activated protein kinase interaction motifs (KIMs).

  5. JNK-dependent acute liver injury from acetaminophen or tumor necrosis factor (TNF) requires mitochondrial Sab protein expression in mice

SH3-Domain Binding Protein 5 (BTK-Associated) (SH3BP5) Protein Profile

Protein Summary

may bind c-Jun N-terminal kinase (JNK)\; may play a role in JNK and Bruton's tyrosine kinase (Btk) mediated signaling pathways

Gene names and symbols associated with SH3BP5

  • SH3 domain binding protein 5 (SH3BP5)
  • SH3-domain binding protein 5 (BTK-associated) (Sh3bp5)
  • SH3-domain binding protein 5 (Sh3bp5)
  • AI606498 protein
  • Sab protein
  • SH3BP-5 protein
  • Vesp18 protein

Protein level used designations for SH3BP5

SH3 domain-binding protein 5 , SH3 domain-binding protein that preferentially associates with BTK , vascular endothelial cell-specific protein 18

GENE ID SPECIES
9467 Homo sapiens
24056 Mus musculus
117186 Rattus norvegicus
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