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anti-SWI/SNF-Related, Matrix-Associated Actin-Dependent Regulator of Chromatin, Subfamily A, Containing DEAD/H Box 1 (SMARCAD1) Antibodies

SMARCAD1 encodes a member of the SNF subfamily of helicase proteins. Additionally we are shipping SWI/SNF-Related, Matrix-Associated Actin-Dependent Regulator of Chromatin, Subfamily A, Containing DEAD/H Box 1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SMARCAD1 56916 Q9H4L7
SMARCAD1 312398 D3Z9Z9
SMARCAD1 13990 Q04692
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Top anti-SWI/SNF-Related, Matrix-Associated Actin-Dependent Regulator of Chromatin, Subfamily A, Containing DEAD/H Box 1 Antibodies at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SMARCAD1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: HepG2 cell lysate 100 μL 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SMARCAD1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: Human heart 100 μL 2 to 3 Days
$289.00
Details
Dog Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated IC, IF, IP, WB Immunofluorescent analysis of SMARCAD1 staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antib Western blot analysis of SMARCAD1 expression in A549 (A), HepG2 (B), mouse kidney (C), mouse lung (D) whole cell lysates. 200 μL 13 to 14 Days
$487.50
Details
Dog Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB   100 μg 4 to 6 Days
$280.00
Details
Human Rabbit Un-conjugated ELISA, IHC, WB ABIN6273728 at 1/100 staining Human breast cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. Western blot analysis of SMARCAD1 expression in HepG2 cell lysate ;,The lane on the left is treated with the antigen-specific peptide. 100 μL 11 to 12 Days
$390.77
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL 2 to 3 Days
$550.00
Details
Human Rabbit Un-conjugated IF/ICC, IHC, WB Immunohistochemistry of paraffin-embedded human lung cancer using SMARCAD1 antibody (ABIN5973461) at dilution of 1/100 (40x lens). Immunofluorescence analysis of A549 cells using SMARCAD1 antibody (ABIN5973461). Blue: DAPI for nuclear staining. 100 μL 11 to 16 Days
$422.09
Details
Human Rabbit Un-conjugated IF, IHC, WB WesternBlot (WB) analysis of SMARCAD1 polyclonal antibody 100 μL 6 to 11 Days
$390.55
Details

Top referenced anti-SWI/SNF-Related, Matrix-Associated Actin-Dependent Regulator of Chromatin, Subfamily A, Containing DEAD/H Box 1 Antibodies

  1. Human Polyclonal SMARCAD1 Primary Antibody for IP, WB - ABIN256707 : Chakraborty, Pandita, Hambarde, Mattoo, Charaka, Ahmed, Iyer, Hunt, Pandita: SMARCAD1 Phosphorylation and Ubiquitination Are Required for Resection during DNA Double-Strand Break Repair. in iScience 2018 (PubMed)
    Show all 2 Pubmed References

More Antibodies against SWI/SNF-Related, Matrix-Associated Actin-Dependent Regulator of Chromatin, Subfamily A, Containing DEAD/H Box 1 Interaction Partners

Human SWI/SNF-Related, Matrix-Associated Actin-Dependent Regulator of Chromatin, Subfamily A, Containing DEAD/H Box 1 (SMARCAD1) interaction partners

  1. Whole-genome sequencing on DNA from affected individuals with Huriez syndrome from three families revealed three not previously reported SNPs in SMARCAD1 gene. Western blot experiments confirmed the reduced expression of Smarcad1 protein in keratinocytes and fibroblasts from patients compared with healthy controls. Study concluded that haploinsufficiency for the skin-specific SMARCAD1 isoform accounts for Huriez syndrome.

  2. Data suggest that retention of SMARCAD1 in nucleus is dependent on interaction of CUE1 domain of SMARCAD1 with RBCC domain of KAP1; these studies were conducted with recombinant proteins expressed in mouse embryonic stem cell line and human somatic cell line. (SMARCAD1 = ATP-dependent helicase-1; KAP1 = KRAB-interacting protein-1)

  3. SMARCAD1 knockdown resulted in a significant decrease in breast cancer cell proliferation and colony formation, leading to the significant inhibition of tumour growth in both the chick embryo and nude mouse xenograft models. This inhibition was due, at least in part, to a decrease in IKKbeta expression.

  4. identifies Smarcad1/Fun30 as an accessory factor for the mismatch repair reaction

  5. A splice variant (c.378+1G>T) in the SMARCAD1 gene co-segregated with Basan syndrome in a large Chinese family.

  6. These results indicate that SMARCAD1 is involved in breast cancer metastasis

  7. BRCA1-BARD1 ligase activity and subsequent SMARCAD1-dependent chromatin remodeling are critical regulators of DNA repair in cancer cells.

  8. These data indicate a pivotal role for the SMARCAD1-skin specific isoform in dermatoglyph formation, ADG and epidermal differientation gene expression

  9. findings unveil an evolutionarily conserved role for the Fun30 and SMARCAD1 chromatin remodellers in controlling end resection, homologous recombination and genome stability in the context of chromatin

  10. The existence of a short isoform of SMARCAD1 exclusively expressed in the skin, is demonstrated.

  11. Findings suggest that chromatin remodeling by SMARCAD1 ensures that silenced loci, such as pericentric heterochromatin, are correctly perpetuated.

  12. Results suggest a novel model for gene regulation via the SMARCAD1/KIAA1122 protein complex.

Mouse (Murine) SWI/SNF-Related, Matrix-Associated Actin-Dependent Regulator of Chromatin, Subfamily A, Containing DEAD/H Box 1 (SMARCAD1) interaction partners

  1. These findings uncover a role for the enzymatic activity of SMARCAD1 in cooperating with KAP1 to silence Endogenous retroviruses.

  2. These data suggest a model in which SMARCAD1 regulates naive pluripotency by interacting with H3 arginine 26 citrullination and suppressing heterochromatin formation.

  3. Results suggest a novel model for gene regulation via the SMARCAD1/KIAA1122 protein complex.

SWI/SNF-Related, Matrix-Associated Actin-Dependent Regulator of Chromatin, Subfamily A, Containing DEAD/H Box 1 (SMARCAD1) Antigen Profile

Protein Summary

This gene encodes a member of the SNF subfamily of helicase proteins. The encoded protein plays a critical role in the restoration of heterochromatin organization and propagation of epigenetic patterns following DNA replication by mediating histone H3/H4 deacetylation. Mutations in this gene are associated with adermatoglyphia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with SMARCAD1

  • SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 (SMARCAD1) antibody
  • SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 S homeolog (smarcad1.S) antibody
  • SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 (smarcad1) antibody
  • SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a (smarcad1a) antibody
  • SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 (Smarcad1) antibody
  • ADERM antibody
  • AV081750 antibody
  • AW226546 antibody
  • D6Pas1 antibody
  • DKFZp468C0919 antibody
  • Etl1 antibody
  • HEL1 antibody
  • mKIAA1122 antibody
  • smarcad1a antibody
  • wu:fi25c01 antibody
  • zgc:113183 antibody

Protein level used designations for SMARCAD1

SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1-like , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1A , ATP-dependent helicase 1 , ATP-dependent helicase SMARCAD1 , enhancer trap locus 1 , enhancer trap locus homolog 1 , etl-1

GENE ID SPECIES
422522 Gallus gallus
443627 Xenopus laevis
461384 Pan troglodytes
548414 Xenopus (Silurana) tropicalis
708691 Macaca mulatta
100173533 Pongo abelii
100354709 Oryctolagus cuniculus
100399527 Callithrix jacchus
100515330 Sus scrofa
100541909 Meleagris gallopavo
100552721 Anolis carolinensis
100598516 Nomascus leucogenys
557875 Danio rerio
56916 Homo sapiens
478480 Canis lupus familiaris
530506 Bos taurus
312398 Rattus norvegicus
13990 Mus musculus
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