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SCRN1 likely encodes a member of the secernin family of proteins. Additionally we are shipping Secernin 1 Antibodies (47) and many more products for this protein.
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Upregulation of SCRN1 is associated with acquired resistance to erlotinib in non-small cell lung cancer.
Luciferase report assay showed that the rs6976789 variant T allele influenced the binding ability of miR (show MLXIP Proteins)-148a. Our results suggested that the SCRN1 rs6976789 polymorphism may play an important role in the GC development and progression
in synovial sarcoma, metastasis-free survival was significantly higher in the group with high secernin-1 expression compared to low expression; results indicate secernin-1 may be used as a biomarker to predict overall and metastasis-free survival
SCRN1 expression is a prognostic factor in colorectal cancer patients
Purified and identified bovine secernin, in addition to bioinformatics analysis of similar proteins in mouse, rat and human.
While acute aerobic exercise increased Sesn1 (show SESN1 Proteins) accumulation and induced a discrete augment of Sesn2 (show SESN2 Proteins) protein content and AMPK (show PRKAA1 Proteins) threonine phosphorylation, chronic exercise reduced the basal levels of Sesn1 (show SESN1 Proteins) and Sesn2 (show SESN2 Proteins) as well as of AMPK (show PRKAA1 Proteins) threonine phosphorylation in the quadriceps muscles of C57BL/6J mice.
Secernin 1 increases both the extent of secretion and increases the sensitivity of mast cells to stimulation with calcium [secernin]
This gene likely encodes a member of the secernin family of proteins. A similar protein in rat functions in regulation of exocytosis in mast cells. Alternatively spliced transcript variants have been described.