Serine/threonine-Protein Kinase MST4 Proteins (MST4)

Mouse (Murine) Serine/threonine-Protein Kinase MST4 (MST4) interaction partners

1. Findings reveal a mechanism by which TRAF6 (show TRAF6 Proteins) is regulated and highlight a role for MST4 in limiting inflammatory responses.

Human Serine/threonine-Protein Kinase MST4 (MST4) interaction partners

1. Our work describes an MST4-ATG4B (show ATG4B Proteins) signaling axis that influences glioblastoma autophagy and malignancy

2. Low MST-4 expression is associated with Graves' disease.

3. these data identify the MST4 kinase as a novel candidate to mediate human pituitary tumorigenesis in a hypoxic environment and position it as a potential therapeutic target.

4. Our results suggest that MST4, STK25 (show STK25 Proteins) and PDCD10 (show PDCD10 Proteins) are upregulated in prostate cancer and may play roles in prostate tumorigenesis. MST4 may be a helpful marker for identifying prostate cancer.

5. Findings reveal a mechanism by which TRAF6 (show TRAF6 Proteins) is regulated and highlight a role for MST4 in limiting inflammatory responses.

6. This study describes the key role of MST4 in facilitating the epithelial-mesenchymal transition process in hepatocellular carcinoma

7. Mutation of this residue was sufficient to switch the phosphorylation site preference for multiple kinases, including the serine-specific kinase PAK4 (show PAK4 Proteins) and the threonine-specific kinase MST4.

8. CCM3 (show PDCD10 Proteins) forms a stable complex with MST4 in vivo to promote cell proliferation and migration synergistically in a manner dependent on MST4 kinase activity.

9. In this review, the germinal center kinase (show MAP4K2 Proteins) III subfamily of mammalian Ste20 (show STK24 Proteins) (sterile 20)-like group of serine/threonine protein kinases comprises Ste20-like (show STK25 Proteins)/oxidant-stress-response kinase 1, MST3 (show STK24 Proteins) mammalian Ste20-like kinase 3 (show STK24 Proteins) and MST4.

10. crystal of the CCM3 (show PDCD10 Proteins)-MST4 C-terminal domain complex belonged to space group P4(1)2(1)2 or P4(3)2(1)2, with unit-cell parameters a = 69.10, b = 69.10, c = 117.57 A