Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5) ELISA Kits

SIGLEC5 encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. Additionally we are shipping SIGLEC5 Antibodies (174) and SIGLEC5 Proteins (20) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SIGLEC5 8778 O15389
Anti-Mouse SIGLEC5 SIGLEC5 83382 Q91Y57
Anti-Rat SIGLEC5 SIGLEC5 292843  
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Showing 2 out of 8 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 8 pg/mL 8-5000 pg/mL 96 Tests Log in to see 2 to 3 Days
Human 3 pg/mL 6.9 pg/mL - 5000 pg/mL   96 Tests Log in to see 5 to 8 Days

Top referenced SIGLEC5 ELISA Kits

  1. Human SIGLEC5 ELISA Kit for Sandwich ELISA - ABIN625088 : Wu, Ding, Han, Arriens, Wei, Han, Pedroza, Jiang, Anolik, Petri, Sanz, Saxena, Mohan: Antibody-Array-Based Proteomic Screening of Serum Markers in Systemic Lupus Erythematosus: A Discovery Study. in Journal of proteome research 2016 (PubMed)

More ELISA Kits for SIGLEC5 Interaction Partners

Human Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5) interaction partners

  1. PSGL1 (show SELPLG ELISA Kits) and Siglec-5 are in close proximity at the leukocyte surface.SPSGL1 is a ligand for Siglec-5 and interacts with Siglec-5 ectodomain.Siglec-5 plays a role in PSGL1 (show SELPLG ELISA Kits)-mediated leukocyte rolling and the inflammatory response in general.

  2. An unbiased screen revealed Hsp70 as a ligand for Siglec-5 and Siglec-14. Hsp70 stimulation through Siglec-5 delivers an anti-inflammatory signal, while stimulation through Siglec-14 is pro-inflammatory.

  3. Data indicate that the Siglec-5/14 genotype influences neutrophil responses to group B Streptococcus.

  4. we found that secretory IgA (show IgA ELISA Kits) is taken up by M cells via the Dectin-1 (show CLEC7A ELISA Kits) receptor, with the possible involvement of Siglec-5 acting as a co-receptor.

  5. These studies demonstrate the Siglec5 carbohydrate recognition domain alone is sufficient for binding sialylated carbohydrates and provide a foundation for further investigation of Siglec5 structure and function.

  6. Siglec-5 expression protects T cells from HIV-1- and apoptosis-induced cell death and contributes to the different outcomes of HIV-1 infection in humans and chimpanzees.

  7. Human Siglec-5 inhibitory receptor and immunoglobulin A (IgA (show IgA ELISA Kits)) have separate binding sites in streptococcal beta protein.

  8. Siglec-5 expression correlates with lack of proliferation in a subset of human cells, and is upregulated by activation of chimpanzee but not human lymphocytes.

  9. expression of Siglec-5 on cells of the myelomonocytic lineage and alteration of its expression by inflammatory stimuli suggest a role for this protein in cell/cell interactions following microbial exposure.

  10. Siglec-5 can be classified as an inhibitory receptor with the potential to mediate SHP-1 and/or SHP-2-dependent signaling in the absence of tyrosine phosphorylation.

Mouse (Murine) Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5) interaction partners

  1. The Siglec-E-deficient dendritic cells were defective for TRIF-mediated IFN-beta (show IFNB1 ELISA Kits) production in response to E. coli infection.

  2. This study demonstrated that virulent parasite Leishmania donovani (AG83+Sias) establish a unique sialic acids-mediated binding and subsequent phagocytosis in the host cell through the selective exploitation of siglec-1 (show SIGLEC1 ELISA Kits).

  3. new data relating to the structure and function of Siglec-E, the major CD33 (show CD33 ELISA Kits)-related Siglec expressed on mouse neutrophils, monocytes, macrophages, and dendritic cells.

  4. indicate that Siglec-9 (show SIGLEC9 ELISA Kits) affects several different signaling pathways in IL-4 (show IL4 ELISA Kits)-stimulated macrophages, which resulted in enhanced induction of Arg1 (show ARG1 ELISA Kits) in Siglec-9 (show SIGLEC9 ELISA Kits)-expressing RAW264 cells

  5. Competitive ELISA assays confirmed the involvement of sulfated (show SULF1 ELISA Kits) epitopes in the affinity between Siglec-E and cruzipain, probably modified by natural protein environment

  6. Data indicate a role for neuraminidase 1 (Neu1) in regulating Siglec E protein-toll-like receptor 4 (TLR4 (show TLR4 ELISA Kits)) interaction and endotoxemia.

  7. Siglec-E-deficient macrophages showed a propensity toward a tumor-promoting M2 polarization, indicating a secondary role of CD33 (show CD33 ELISA Kits)-related Siglecs in limiting cancer-promoting inflammation and tumor growth.

  8. siglec-E functions as an inhibitory receptor of neutrophils via positive regulation of NADPH oxidase (show NOX1 ELISA Kits) activation and ROS (show ROS1 ELISA Kits) production

  9. These results suggest that sSiglec-9 has an antitumor benefit against MUC1 (show MUC1 ELISA Kits)-expressing tumor in the transgenic mice.

  10. Siglec-9 (show SIGLEC9 ELISA Kits) expressed on immune cells may play a role as a potential counterreceptor for MUC1 (show MUC1 ELISA Kits) and that this signaling may be another MUC1 (show MUC1 ELISA Kits)-mediated pathway and function in parallel with a growth factor-dependent pathway.

SIGLEC5 Antigen Profile

Antigen Summary

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion.

Gene names and symbols associated with SIGLEC5

  • sialic acid binding Ig like lectin 5 (SIGLEC5) antibody
  • sialic acid binding Ig-like lectin E (Siglece) antibody
  • sialic acid-binding Ig-like lectin 5 (LOC100597560) antibody
  • sialic acid binding Ig-like lectin 5 (Siglec5) antibody
  • CD33L2 antibody
  • Cd170 antibody
  • mSiglec-E antibody
  • OB-BP2 antibody
  • OBBP2 antibody
  • SIGLEC-5 antibody
  • Siglec5 antibody
  • Siglec9 antibody
  • Siglec12 antibody
  • Siglecl1 antibody

Protein level used designations for SIGLEC5

CD33 antigen-like 2 , OB-binding protein 2 , obesity-binding protein 2 , sialic acid-binding Ig-like lectin 5 , sialic acid-binding immunoglobulin-like lectin 5 , MIS , SIGLEC-like 1 , myeloid inhibitory siglec , sialic acid binding Ig-like lectin 5 , sialic acid-binding Ig-like lectin 12 , sialic acid-binding Ig-like lectin E , sialic acid-binding Ig-like lectin-like 1 , sialic acid-binding immunoglobulin-like lectin E , siglec-12 , siglec-5 , siglec-E , siglec-L1

8778 Homo sapiens
83382 Mus musculus
100597560 Nomascus leucogenys
292843 Rattus norvegicus
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