Small Nuclear Ribonucleoprotein Polypeptide N Proteins (SNRPN)

The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure.

• small nuclear ribonucleoprotein polypeptide-like (SNRPL)
• small nuclear ribonucleoprotein polypeptides B and B1 (snrpb)
• small nuclear ribonucleoprotein polypeptide N (SNRPN)
• small nuclear ribonucleoprotein N (Snrpn)
• small nuclear ribonucleoprotein polypeptide N (Snrpn)
• Show all gene names
• small nuclear ribonucleoparticle-associated protein (snRNP) mRNA, clone Sm51 (snrpn)
• SNRPN upstream reading frame (SNURF)
• Small nuclear ribonucleoprotein-associated protein N (SNRPN)

• 2410045I01Rik protein
• FE 294 protein
• FE294 protein
• FE 294 psi protein
• FE294 psi protein
• Show all synonym aliases
• HCERN3 protein
• Peg4 protein
• PWCR protein
• Pwcr1 protein
• QflA-11237 protein
• QtrA-10022 protein
• RT-LI protein
• SM-D protein
• Sm-N protein
• SmN protein
• SNRB' protein
• snRNP-N protein
• SNRPB' protein
• SNRPN protein
• SNURF protein
• SNURF-SNRPN protein
• zgc:77315 protein

sm protein B' , sm-B' , smB' , small nuclear ribonucleoprotein B , small nuclear ribonucleoprotein B' , small nuclear ribonucleoprotein polypeptide B/B' , small nuclear ribonucleoprotein-associated protein B' , snRNP-B' , snRNP-associated protein , SM protein N , sm protein D , small nuclear ribonucleoprotein-associated protein N , tissue-specific splicing protein , sm protein N , sm-D , sm-N , snRNP-N , tissue-specific-splicing protein , FE294 gene for snRNP-associated polypeptide N , FE294 psi pseudogene , smN , small nuclear ribonucleoparticle-associated protein (snRNP) mRNA clone Sm51 , small nuclear ribonucleoparticle-associated protein (snRNP) mRNA, clone Sm51 , small nuclear ribonucleoprotein N , SNRPN upstream reading frame , SNRPN upstream reading frame protein , small nuclear ribonucleoprotein polypeptide N , SNRPN upstream reading frame product , Sm protein N