SNRPN Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2732320

Product Details

Target: SNRPN (Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This SNRPN protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human snRNP-N / Sm-N (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: SNRPN (Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN))

Alternative Name: Snrnp-N,sm-N (SNRPN Products)

Synonyms: SNRB' Protein, SNRPB' Protein, Snrpn Protein, zgc:77315 Protein, HCERN3 Protein, PWCR Protein, RT-LI Protein, SM-D Protein, SMN Protein, SNRNP-N Protein, SNURF-SNRPN Protein, sm-N Protein, 2410045I01Rik Protein, Peg4 Protein, Pwcr1 Protein, FE 294 Protein, FE 294 psi Protein, FE294 Protein, FE294 psi Protein, SNURF Protein, SNRPN Protein, QflA-11237 Protein, QtrA-10022 Protein, Sm-N Protein, SmN Protein, snRNP-N Protein, small nuclear ribonucleoprotein polypeptide-like Protein, small nuclear ribonucleoprotein polypeptides B and B1 Protein, small nuclear ribonucleoprotein polypeptide N Protein, small nuclear ribonucleoprotein N Protein, small nuclear ribonucleoparticle-associated protein (snRNP) mRNA, clone Sm51 Protein, SNRPN upstream reading frame Protein, Small nuclear ribonucleoprotein-associated protein N Protein, SNRPL Protein, snrpb Protein, SNRPN Protein, Snrpn Protein, snrpn Protein, SNURF Protein

Background: The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure.

Molecular Weight: 24.4 kDa

NCBI Accession: NP_073716