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SLC3A2 is a member of the solute carrier family and encodes a cell surface, transmembrane protein. Additionally we are shipping SLC3A2 Antibodies (393) and SLC3A2 Proteins (29) and many more products for this protein.
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Human SLC3A2 ELISA Kit for Sandwich ELISA - ABIN823344
Chen, Chung, Wu, Ng, Yu, Tsai, Chang, Liang, Tsui, Chen: Comparative Tissue Proteomics of Microdissected Specimens Reveals Novel Candidate Biomarkers of Bladder Cancer. in Molecular & cellular proteomics : MCP 2015
Data suggest that SLC3A2-NRG1 (show NRG1 ELISA Kits) should be considered a therapeutic target for patients with invasive mucinous adenocarcinoma of the lung (IMA).
These results demonstrate a novel fundamental role of LAT1 (show LAT ELISA Kits) to support the protein expression of 4F2hc via a chaperone-like function in chorionic trophoblasts.
SLC3A2 is upregulated in osteosarcoma and plays a crucial role in tumor growth.
Expression levels of CD98 and beta1-integrin-A (the activated form of beta1-integrin) were significantly increased in hepatocellular carcinoma (HCC) tissues relative to those of normal liver tissues.
Data suggest that increased CD98 (4F2hc) expression plays an essential role in tumor aggressiveness and metastasis.
Study demonstrated that the mRNA expression levels of the two system xc- subunits, SLC7A11 (show SLC7A11 ELISA Kits) and SLC3A2, in peripheral white blood cells are lowered in patients with schizophrenia than healthy individuals
ubiquitylation and the resulting downregulation of CD98 can limit cell proliferation and clonal expansion.
exposure to diesel exhaust particle extract induces functional overexpression of the amino acid transporter LAT1 (show LAT ELISA Kits)/CD98hc in lung cells
The detergent-induced stabilization of the purified human 4F2hc-LAT2 complex presented here paves the way towards its crystallization and structure determination at high-resolution
HSV-1 recruited cellular fusion regulatory proteins CD98hc and beta1 integrin to the nuclear membrane for viral de-envelopment fusion.
Slc3a2 is required for branched-chain amino-acid-dependent maintenance of Treg cells.
CD98hc expression in vascular smooth muscle cells contributes to the formation of plaques that are morphologically more stable, and thereby protects against atherothrombosis.
These results demonstrate a novel fundamental role of LAT1 (show SLC7A5 ELISA Kits) to support the protein expression of 4F2hc via a chaperone-like function in chorionic trophoblasts.
CD98 is required for endothelial cell growth. CD98-specific reagents could have a dual anticancer effect: directly by inhibiting tumor cell proliferation and indirectly by preventing tumor angiogenesis
Taken together, our data indicate that T cell-specific deletion of CD98hc can contribute to the prevention of GvHD development due to the attenuation of lymphocyte migration and by increasing the generation of Treg cells.
data establish CD98hc as a master protective gene at the cross-road of redox control and AA availability, making it a relevant therapeutic target in cancer.
CD98hc mediated this stiffness sensing by increasing Rho kinase (show ROCK2 ELISA Kits) (ROCK) activity.
Mice lacking CD98hc in B cells are protected from experimental autoimmune encephalomyelitis.
CD98 heavy chain is crucial for T cell-mediated autoimmune colitis. CD98 heavy chain deficiency in T cells is involved in increasing induced regulatory T cells.
This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.
4F2 cell-surface antigen heavy chain
, CD98 heavy chain
, antigen defined by monoclonal antibody 4F2, heavy chain
, antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43
, lymphocyte activation antigen 4F2 large subunit
, monoclonal antibody 44D7
, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
, antigen identified by monoclonal antibodies 4F2
, solute carrier family 3, member 2
, blood-brain barrier large neutral amino acid transporter heavy chain 4F2
, CD98 antigen
, type II transmembrane protein