anti-Solute Carrier Organic Anion Transporter Family, Member 2B1 (SLCO2B1) Antibodies

This locus encodes a member of the organic anion-transporting polypeptide family of membrane proteins. Additionally we are shipping SLCO2B1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SLCO2B1 11309 O94956
SLCO2B1 101488 Q8BXB6
SLCO2B1 140860 Q9JHI3
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Top anti-SLCO2B1 Antibodies at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-SLCO2B1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  HepG2 cell lysate SLCO2B1 is strongly supported by BioGPS gene expression data to be expressed in Human HepG2 cells Host:  Rabbit  Target Name:  SLCO2B1  Sample Tissue:  Human Hela Whole Cell  Antibody Dilution:  1ug/ml 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated ICC, IF, WB Western Blot: SLCO2B1 Antibody [NBP1-59811] - Human Fetal Lung, Antibody Dilution: 1.0 ug/ml. Western Blot: SLCO2B1 Antibody [NBP1-59811] - Human Adult Placenta, Antibody Dilution: 1.0 ug/ml. 100 μL Log in to see 8 to 11 Days
$488.73
Details
Cow Rabbit Un-conjugated WB Host:  Rabbit  Target Name:  SLCO2B1  Sample Type:  U937 Whole Cell lysates  Antibody Dilution:  1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse small intestine labeled with Anti SLCO2B1 Polyclonal Antibody, Unconjugated (ABIN751048) followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Anti-SLCO2B1/OATPB Polyclonal Antibody, Unconjugated (ABIN751048) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$329.45
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of HepG2 and mouse liver cells, using SLCO2B1 antibody. Western blot analysis of extracts of various cell lines, using SLCO2B1 antibody (ABIN4905218) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 8s. 100 μL Log in to see 11 to 13 Days
$366.77
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry-Paraffin: SLCO2B1 Antibody [NBP1-80979] - Staining of human testis shows nuclear and cytoplasmic positivity in Leydig cells. Western Blot: SLCO2B1 Antibody [NBP1-80979] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4 0.1 mL Log in to see 34 Days
$494.38
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with SLCO2B1 polyclonal antibody . Immunohistochemical staining of human testis with SLCO2B1 polyclonal antibody  shows nuclear and cytoplasmic positivity in Leydig cells. 100 μL Log in to see 11 to 12 Days
$577.33
Details
Human Rabbit Un-conjugated WB SLCO2B1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 9 to 11 Days
$473.93
Details
Human Rabbit Cy3 IF (p)   100 μL Log in to see 14 to 21 Days
$428.45
Details

Top referenced anti-SLCO2B1 Antibodies

  1. Human Polyclonal SLCO2B1 Primary Antibody for IF (p), IHC (p) - ABIN751048 : Yamamoto, Sato, Yukita, Yasuda, Omodaka, Ryu, Fujita, Nishiguchi, Machida, Nakazawa: The neuroprotective effect of latanoprost acts via klotho-mediated suppression of calpain activation after optic nerve transection. in Journal of neurochemistry 2016 (PubMed)

  2. Human Polyclonal SLCO2B1 Primary Antibody for IHC (p), WB - ABIN5588358 : Mooij, de Koning, Lindenbergh-Kortleve, Simons-Oosterhuis, van Groen, Tibboel, Samsom, de Wildt: Human Intestinal PEPT1 Transporter Expression and Localization in Preterm and Term Infants. in Drug metabolism and disposition: the biological fate of chemicals 2016 (PubMed)

More Antibodies against SLCO2B1 Interaction Partners

Human Solute Carrier Organic Anion Transporter Family, Member 2B1 (SLCO2B1) interaction partners

  1. In the study, nine critical amino acids were identified within transmembrane domain 1 of OATP2B1. Most of these residues are important for substrate interaction, whereas F51 is crucial for correct folding of the transporter protein.

  2. Thyroid hormones are substrates and transcriptional regulators of OATP2B1.

  3. PDZK1 directly interacts with OATP2B1 resulting in a change of the amount of transporter in the membrane, and thereby in an increased transport function.

  4. Report inhibition of organic anion-transporting polypeptide 2B1 by crude drug extracts used in Japanese traditional Kampo medicines.

  5. Significant interaction between SLCO2B1 genotypes and treatment over time for parasitemia clearance rate on day 2 were observed.

  6. It shows high expression of OATP2B1 mRNA in human pancreatic islets.

  7. genetic association studies in population in South Korea: Data suggest that an SNP in SLCO2B1 (c.935G>A, rs12422149) is associated with lipid-lowering response to rosuvastatin (an HMG-CoA reductase inhibitor) in subjects with hypercholesterolemia.

  8. Data suggest that OATP1B1, OATP1B3, and OATP2B1 participate in transport of perfluoroalkyl acids in hepatocytes; environmental pollutants transported include PFBS (perfluorobutane sulfonate), PFHxS (perfluorohexane sulfonate), and PFOS (perfluorooctane sulfonate).

  9. The OATP2B1 was primarily found in beta cells, suggesting a distinct expression pattern for OATP1B3 and OATP2B1 in islets.

  10. OATP1A2, OATP1B1, and OATP2B1 can mediate cellular uptake of ochratoxin A, which could aggravate OTA toxicity.

  11. results indicate that insulin acts on the small intestine to increase OATP2B1-mediated absorption

  12. Data show that prostaglandin E3 (PGE3) uptake by prostaglandin transporter OATP2A1-expressing HEK293 cells (HEK/2A1) was the highest and followed by SLCO2B1 (HEK/1B1).

  13. Results identified interethnic differences of genetic variations of the SLCO1B1, SLCO1B3, and SLCO2B1 genes in Korean population compared with other ethnic groups.

  14. OATP2B1 contributes to the uptake of SN-38 by intestinal tissues, triggering gastrointestinal toxicity.

  15. The association of SNP rs1077858 with OS may be a result of differential SLCO2B1 expression and the consequent increased uptake of DHEAS and subsequent resistance to ADT, which, in turn, may contribute to decreased OS.

  16. Suggest that OATP2B1 is involved in cell proliferation by increasing the amount of estrogen in ER1-positive breast cancer cells.

  17. OATP2B1 as a determinant of pharmacokinetics in the coronary artery.

  18. These results suggest that OATP2B1 plays an important role in the stereoselective pharmacokinetics of fexofenadine and that one-time apple juice ingestion probably inhibits intestinal OATP2B1-mediated transport of both enantiomers

  19. The genotypes of the two other SLCOs,SLCO1B3 and SLCO2B1, did not show any association with bladder cancer susceptibility

  20. SLCO2B1 rs12422149 variants could provide prognostic value for prostate cancer patients treated with androgen deprivation therapy (ADT) and influence ethnic differences in response to ADT.

Mouse (Murine) Solute Carrier Organic Anion Transporter Family, Member 2B1 (SLCO2B1) interaction partners

  1. OATP2B1 downregulation in mouse brain can suppress tolerance via blocking morphine and M6G brain transport. These findings might help to improve the pharmacological effects of morphine

  2. OATP2B1 contributes to the uptake of SN-38 by intestinal tissues, triggering gastrointestinal toxicity.

SLCO2B1 Antigen Profile

Protein Summary

This locus encodes a member of the organic anion-transporting polypeptide family of membrane proteins. The protein encoded by this locus may function in regulation of placental uptake of sulfated steroids. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with SLCO2B1

  • solute carrier organic anion transporter family member 2B1 (SLCO2B1) antibody
  • solute carrier organic anion transporter family member 2B1 (slco2b1) antibody
  • solute carrier organic anion transporter family, member 2B1 (slco2b1) antibody
  • solute carrier organic anion transporter family member 2B1 L homeolog (slco2b1.L) antibody
  • solute carrier organic anion transporter family, member 2b1 (Slco2b1) antibody
  • AI060904 antibody
  • AI852653 antibody
  • DKFZp469P0119 antibody
  • im:7158298 antibody
  • moat1 antibody
  • OATP-B antibody
  • OATP2B1 antibody
  • OATPB antibody
  • Slc21a9 antibody
  • wu:fi40d02 antibody
  • zgc:123236 antibody

Protein level used designations for SLCO2B1

solute carrier organic anion transporter family, member 2B1 , solute carrier organic anion transporter family member 2B1 , organic anion-transporting polypeptide 2B1 , solute carrier organic anion transporter family member 2B1-like , Oatp2b1 , solute carrier organic anion transporter family, member 2b1 , OATP-RP2 , organic anion transporter B , organic anion transporter polypeptide-related protein 2 , solute carrier family 21 (organic anion transporter), member 9 , organic anion transporting polypeptide 2b1 , solute carrier family 21 member 9 , multispecific organic anion transporter 1 , organic anion transporter moatp1

GENE ID SPECIES
466711 Pan troglodytes
485192 Canis lupus familiaris
694829 Macaca mulatta
100009692 Equus caballus
100125037 Xenopus (Silurana) tropicalis
100173323 Pongo abelii
100386092 Callithrix jacchus
100477792 Ailuropoda melanoleuca
792084 Danio rerio
734942 Xenopus laevis
419051 Gallus gallus
11309 Homo sapiens
317704 Bos taurus
101488 Mus musculus
140860 Rattus norvegicus
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