SPG21 Proteins

Protein Summary

The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with Spastic Paraplegia 21 Proteins (SPG21)

• SPG21, maspardin (SPG21) antibody
• SPG21, maspardin (Spg21) antibody
• spastic paraplegia 21 (autosomal recessive, Mast syndrome) (SPG21) antibody
• SPG21, maspardin S homeolog (spg21.S) antibody
• spastic paraplegia 21 (autosomal recessive, Mast syndrome) (spg21) antibody

• ACP33 antibody
• BM-019 antibody
• C78576 antibody
• D9Wsu18e antibody
• GL010 antibody
• Show all synonym aliases
• Maspardin antibody
• MAST antibody
• wu:fd07h02 antibody
• zgc:73091 antibody

Protein level used designations for Spastic Paraplegia 21 Proteins (SPG21)

acid cluster protein 33 , maspardin , spastic paraplegia 21 autosomal recessive Mast syndrome protein homolog , spastic paraplegia 21 , spastic paraplegia 21 homolog , spastic paraplegia 21, maspardin (autosomal recessive, Mast syndrome) , spastic paraplegia 21 (autosomal recessive, Mast syndrome)