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Sperm Associated Antigen 1 Proteins

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization.

6 results:

Sperm Associated Antigen 1 (SPAG1) (AA 1-926) protein (His tag) Protein

SPAG1 Origin: Human Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3095660
$14,592.92
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 70 Business Days
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Sperm Associated Antigen 1 (SPAG1) (AA 1-901) protein (His tag) Protein

SPAG1 Origin: Mouse Source: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Catalog No. ABIN3136094
$14,592.92
Plus shipping costs $45.00 and $24.00 dry ice
1 mg (More quantities available)
local_shipping Shipping to: United States
Will be delivered in 70 Business Days
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Sperm Associated Antigen 1 (SPAG1) (AA 1-365) protein (T7 tag,His tag) Protein

SPAG1 Origin: Human Source: Escherichia coli (E. coli) Recombinant ≥ 99 % ELISA, IP, SDS, WB
Catalog No. ABIN6238698
$406.00
Plus shipping costs $45.00
50 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 15 to 18 Business Days
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Sperm Associated Antigen 1 (SPAG1) (AA 175-283) protein (GST tag) Protein

SPAG1 Origin: Human Source: Wheat germ Recombinant AP, AA, ELISA, WB
Catalog No. ABIN1321052
$414.29
Plus shipping costs $45.00 and $24.00 dry ice
10 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 12 Business Days
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Sperm Associated Antigen 1 (SPAG1) Protein Protein

SPAG1 Origin: Human Source: Escherichia coli (E. coli) Recombinant ELISA, IP, SDS, WB
Catalog No. ABIN6118303
$681.76
Plus shipping costs $45.00
100 μg (More quantities available)
local_shipping Shipping to: United States
Delivery in 11 to 18 Business Days
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Sperm Associated Antigen 1 (SPAG1) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag) Protein

SPAG1 Origin: Human Source: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Catalog No. ABIN2732486
$932.80
Plus shipping costs $45.00 and $24.00 dry ice
20 μg
local_shipping Shipping to: United States
Will be delivered in 11 Business Days
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  • Type Protein
    • Protein
  • Target Sperm Associated Antigen 1 (SPAG1)
    • Sperm Associated Antigen 1 (SPAG1)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Growth Hormone 1 (GH1)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Lipoyl synthase lipA
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Leptin (LEP)
    • Interleukin 8 (IL8)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • Hemoglobin, alpha 1 (HBA1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • Prolactin (PRL)
    • Interleukin 13 (IL13)
    • CD40 Ligand (CD40LG)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Interleukin 15 (IL15)
    • Porphobilinogen Deaminase (HEMC)
    • beta-2-Microglobulin (B2M)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Adiponectin (ADIPOQ)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Interleukin 33 (IL33)
    • Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1)
  • Application
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Immunoprecipitation (IP)
    • Crystallization (Crys)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Protein Interaction (PI)
    • Standard (STD)
  • Reactivity
    • Human
    • Mouse
  • Images available
  • Host
    • Escherichia coli (E. coli)
    • Insect Cells
    • HEK-293 Cells
    • Wheat germ
  • Binding Specificity
    • AA 1-365
    • AA 1-901
    • AA 1-926
    • AA 175-283
    • Transcript Variant 1
  • Conjugate
    • Un-conjugated
    • His tag
    • GST tag
    • Myc-DYKDDDDK Tag
    • T7 tag,His tag
  • Protein Type
    • Recombinant
  • Format
    • Liquid

Sperm Associated Antigen 1 (SPAG1) Protein Profile

Protein Summary

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein.

Gene names and symbols associated with SPAG1

  • sperm associated antigen 1 (SPAG1) antibody
  • sperm associated antigen 1a (spag1a) antibody
  • sperm associated antigen 1 (CpipJ_CPIJ006297) antibody
  • sperm associated antigen 1 (spag1) antibody
  • sperm associated antigen 1 (Spag1) antibody
  • cb1089 antibody
  • HSD-3.8 antibody
  • MGC162178 antibody
  • SP75 antibody
  • TPIS antibody
  • wu:fj78g10 antibody

Protein level used designations for SPAG1

sperm associated antigen 1 , sperm-associated antigen 1 , TPR-containing protein involved in spermatogenesis , infertility-related sperm protein Spag-1 , tetratricopeptide repeat-containing protein , HSD-3.8

GENE ID SPECIES
420249 Gallus gallus
464314 Pan troglodytes
564953 Danio rerio
607063 Canis lupus familiaris
6038177 Culex quinquefasciatus
100038144 Xenopus (Silurana) tropicalis
6674 Homo sapiens
26942 Mus musculus
315033 Rattus norvegicus
530104 Bos taurus

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